Evolution of helium bubbles in nickel-based alloy by post-implantation annealing

Nickel-based alloys have been considered as candidate structural materials used in generation IV nuclear reactors serving at high temperatures. In the present study, alloy 617 was irradiated with 180-keV helium ions to a fluence of 3.6×10¹⁷ ions/cm² at room temperature. Throughout the cross-section transmission electron microscopy (TEM) image, numerous over-pressurized helium bubbles in spherical shape are observed with the actual concentration profile a little deeper than the SRIM predicted result. Post-implantation annealing was conducted at 700 ℃ for 2 h to investigate the bubble evolution. The long-range migration of helium bubbles occurred during the annealing process, which makes the bubbles of the peak region transform into a faceted shape as well. Then the coarsening mechanism of helium bubbles at different depths is discussed and related to the migration and coalescence (MC) mechanism. With the diffusion of nickel atoms slowed down by the alloy elements, the migration and coalescence of bubbles are suppressed in alloy 617, leading to a better helium irradiation resistance.     

专有服务机制下提供免费体验服务的服务系统优化设计研究

通过提供免费的体验服务,服务系统可以吸引潜在顾客成为忠实顾客。本文考虑专有服务机制下提供免费体验服务和付费(常规)服务的服务系统,基于顾客的延时敏感特性,利用排队论的矩阵分析方法和谱扩展方法,研究服务系统的相关性能指标以及服务系统的优化设计,进而构建服务提供商利润函数并通过数值实例来获得免费体验服务的最优服务速率以及常规服务收取的最优服务费用,并为服务提供商提供相应的管理启示。研究表明,当越来越多的体验顾客转为付费顾客时,服务提供商需要降低体验服务的服务速率,来缓解系统的拥堵情况,减少顾客的逗留时间,并且服务提供商需要降低常规服务的服务费来弥补顾客因拥堵而造成的服务延迟。新到达顾客选择体验服务的人数越多时,服务提供商需要大幅度降低常规服务的收费标准,来吸引体验顾客成为付费顾客。     

低能X射线工业CT图像杯状伪影校正

为了去除X射线工业CT图像中的杯状伪影,提高CT图像的识别能力和量化分析精度,提出一种基于分度投影和权函数的射束硬化校正方法。首先分析得出杯状伪影主要是由X射线连续谱穿过被测物体过程中出现的射束硬化所导致。然后扫描阶梯模型,采集不同厚度下的投影数据并求出线衰减系数,通过拟合曲线,得到硬化模型函数和权函数校正模型函数,并确定权函数。接着,扫描被测圆柱形工件,采集不同分度下的投影数据。最后,针对每一个分度投影数据,采用权函数与当前分度投影数据乘积的方法进行硬化校正。对含有杯状伪影的实际CT图像进行了校正实验,结果表明,与多项式拟合法相比,该方法校正后的灰度图像没有放大噪声,且信噪比提高3.29%,有效地消除了杯状伪影,同时较好地保留了图像边界细节。     

低能X射线工业CT小间隔信号采集系统

为克服探测器阵列获取速度慢、重建图像精度低的缺点,并能在低能X射线的小焦点/微焦点CT系统中完成对小型精密复杂器件的检测,研究了低能X射线工业CT的小间隔信号采集系统。系统选取DT公司0.2 mm像素尺寸、高集成度、扫描速度快的X-CARD 0.2-256G为探测器,Altera公司的Cyclone EP1C3T为主控芯片,Intel公司的LXT972A为以太网控制芯片。从数据传输的可靠、稳定、高效率角度出发,用模块化的方法给出了系统的硬件设计,用有限状态机技术完成了系统的逻辑单元设计,并对系统的动态范围进行了测试。测试实验结果表明,系统的动态范围大于4000,能够检测精密器件、准确迅速地完成信号的采集传输,满足实际工业CT对信号采集的要求。     

Simultaneous determination of eleven amphenicols and antiviral drugs in aquatic products by ultra-high performance liquid chromatography-tandem mass spectrometry coupled with PRIME HLB solid phase extractionEI北大核心CSCD

An efficient ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method was established for the simultaneous determination of 11 amphenicols and antiviral drugs in aquatic products including fish, shrimp, soft-shell turtle and shellfish samples. Each sample was dispersed with 4%(w/w)sodium chloride solution, and extracted with 2%(V/V) ammonia-ethyl acetate solution. After the concentration of the extract, the residue was redissolved in 0.2%(V/V) aqueous solution of formic acid-acetonitrile (20∶80, V∶V), purified with Oasis PRIME HLB cartridge, and detected by UPLC-MS/MS. The samples were analyzed directly on the ZORBAX RRHD Eclipse Plus C18 column using 5 mmol/L ammonium formate and acetonitrile as mobile phase. The quantitative determination of the analytes was carried out under the multiple reaction monitoring mode with positive and negative electrospray ionization using internal standard method. Results showed that there were good linear relationships for all analytes in the corresponding concentration ranges, with the correlation coefficients not less than 0.996. The limits of quantification ranged from 0.2 to 2.0 µg/kg. The average spiked recoveries were between 84.6% and 110% with the relative standard deviations of 1.0% to 14%. The method, which has been used in risk monitoring, is suitable for rapid determination of amphenicols and antiviral drugs in aquatic products. © 2023, Youke Publishing Co.,Ltd. All rights reserved.     

超高效液相色谱-四极杆-飞行时间质谱法快速筛查和确证渔药中86种非法添加化学品

建立了超高效液相色谱-四极杆-飞行时间质谱法快速筛查与确证渔药中86种非法添加禁限用药物的方法。渔药以80%(v/v)乙腈水溶液进行提取,通过稀释降低基质效应,采用ACQUITY PREMIER HSS T3色谱柱进行分离,以甲醇和0.1%甲酸水溶液作为流动相进行梯度洗脱,采用电喷雾双喷离子源(Dual AJS ESI)正离子模式分析检测。建立了86种药物的一级精确质量数据库和二级碎片质谱库。在全扫描采集模式下,以化合物的色谱保留时间、精确质量数、同位素分布和同位素丰度比定性;在Target MS/MS采集模式下,通过二级碎片离子的匹配进一步确证化合物,以准分子离子峰的峰面积定量,实现渔药样品中多目标药物的快速定性定量分析。86种药物在各自的线性范围内均呈现良好的线性关系,相关系数均大于0.99,中草药制剂和抗生素粉剂的定量限(LOQ)范围分别为1~15 mg/kg和5~75 mg/kg,添加回收率范围为76.8%~112.1%,相对标准偏差(RSD, n=3)小于11.7%。该方法快速、简便、准确、灵敏,适用于不同种类渔药中禁限用非法添加药物的高通量筛查。将该方法应用于浙江省渔用投入品质量安全监督抽检项目中,共筛查60个样品,其中8种中草药制剂筛查出说明书中未明确标明的药物成分,1种抗生素粉剂未检出有效成分。该研究为渔药的质量安全监控提供了有效的技术手段。