排序方式: 共有16条查询结果,搜索用时 15 毫秒
1.
Allam Vinaykumar Chinthala Muniraju Batchu Venkateswara Rao 《Tetrahedron letters》2017,58(11):1075-1077
Total synthesis of (?)-zeylenol, a key intermediate for the synthesis of (+)-pipoxide, (?)-uvarigranol G and (?)-tonkinenin A was achieved from commercially available starting material d-mannose. The key steps are mixed aldol condensation, Grignard reaction, ring closing metathesis and regioselective benzoylation. 相似文献
2.
Sridhar Madabhushi Kondal Reddy GodalaRaveendra Jillella Kishore Kumar Reddy MalluNarsaiah Chinthala 《Tetrahedron letters》2014
The synthesis of highly functionalized 2,3-dihydroisoxazoles by a one-pot multicomponent reaction of an aldehyde, hydroxamic acid, and malononitrile or methyl cyanoacetate is described. 相似文献
3.
Yakaiah Chinthala Manjulatha K Pooja Sharma Satya Srinivas Kvn Kotesh Jonnala Niranjana Kumar Arigari Feroz Khan Setty Oh 《Journal of heterocyclic chemistry》2016,53(6):1902-1910
A series of new andrographolide‐1,2,3‐triazole derivatives, 3a , 3b , 3c , 3d , 3e , 3f , 3g , 3h , 3i , 3j , 3k , were synthesized from a natural bioactive labdane type diterpenoid, andrographolide. All the derivatives were screened against human cancer cell lines MCF7, MDA‐MB‐231, COLO205, HepG2, K562, Hela, and HEK293 to evaluate their cytotoxic activity. All the compounds showed anticancer activity selectively against K562 cell line, with IC50 values ranging from 8.00 to 17.11 µM, and are inactive against the rest of the cell lines. Compounds 3c and 3d showed significant cytotoxicity among the synthesized derivatives. The in silico docking studies revealed compounds 3b and 3d with high binding affinity against the cancer target, transient receptor potential vanilloid 1. 相似文献
4.
Sridhar Madabhushi Raveendra JillellaKondal Reddy Godala Kishore Kumar Reddy MalluChina Ramanaiah Beeram Narsaiah Chinthala 《Tetrahedron letters》2012,53(39):5275-5279
An efficient and simple method for the synthesis of 2,2-disubstituted-2H-chromenes by one-step cyclocondensation of a phenol with a variety of 1,1-disubstituted propargyl alcohols using BF3·Et2O as the catalyst is described. 相似文献
5.
Madabhushi Sridhar Chinthala Narsaiah Vishnu M. Ankathi Shrinandan N. Asthana 《Tetrahedron letters》2009,50(16):1777-1133
Hexafluoroacetone trihydrate was shown to undergo an efficient carbonyl-ene reaction with a variety of alkenes in the presence of molecular sieves under microwave heating and conventional heating producing hexafluoroisopropanol functionalized derivatives in high yields. 相似文献
6.
Sridhar Madabhushi Kondal Reddy GodalaChina Ramanaiah Beeram Narsaiah Chinthala 《Tetrahedron letters》2012,53(41):5539-5540
An efficient stereoselective total synthesis of botryolide-E by a chiral-pool approach is described. 相似文献
7.
Oxidative homo coupling of various arylmagnesium bromides in the presence of ZnBr2 gave the corresponding symmetrical biaryls in moderate to good yields at room temperature. An efficient method under mild conditions without the use of reoxidant is described. 相似文献
8.
Madabhushi Sridhar Beeram China Ramanaiah Chinthala Narsaiah Mudam Kumara Swamy Bellam Mahesh Mallu Kishore Kumar Reddy 《Tetrahedron letters》2009,50(51):7166-5982
Symmetrical disiloxanes were prepared in high yields by air oxidation of mono, di, and trihydrosilanes under Lewis acid catalysis. 相似文献
9.
Madabhushi Sridhar Chinthala NarsaiahJillella Raveendra Godala Kondal ReddyMallu Kishore Kumar Reddy Beeram China Ramanaiah 《Tetrahedron letters》2011,52(36):4701-4704
An efficient synthesis of oximes by reaction of carbonyls with acetohydroxamic acid using BF3·OEt2 as a catalyst is described. 相似文献
10.
Kumar CP Gopal NO Wang TC Wong MS Ke SC 《The journal of physical chemistry. B》2006,110(11):5223-5229
An in situ electron paramagnetic resonance (EPR) study has been carried out for anatase (Hombikat UV100) and rutile TiO(2) nanoparticles at liquid helium (He) temperature (4.2 K) under UV irradiation. Rutile titania was synthesized by ultrasonic irradiation with titanium tetrachloride (TiCl(4)) as the precursor. XRD and Raman results evidence the crystallinity of titania phases. The nature of trapped electrons and holes has been investigated by EPR spectroscopy under air and vacuum conditions. Illumination of TiO(2) powder (anatase and rutile) at 4.2 K resulted in the detection of electrons being trapped at Ti(4+) sites within the bulk and holes trapped at lattice oxide ions at the surface. The stability of electron traps was very sensitive to temperature in both phases of TiO(2). The annealing kinetics of the EPR detected radicals has been studied from 4.2 K to ambient temperature and also for calcined titania particles from 523 to 1273 K. 相似文献