Effect of Cold Atmospheric Plasma Jet and Gamma Radiation Treatments on Gingivobuccal Squamous Cell Carcinoma and Breast Adenocarcinoma Cells

Surgery, chemotherapy and radiotherapy, the conventional treatment modalities of cancer though successful are limited by presence of residual tumor cells, toxic side-effects and treatment resistance, thus raising the need for investigating other novel approaches. Here, we have used a cold atmospheric plasma (CAP) jet and assessed the in vitro efficacy in gingivobuccal squamous cell carcinoma (GB-SCC) – ITOC-03, breast adenocarcinoma—MCF7 and HEK293 cells. Cells lines were subjected to varying doses of ionizing radiation (0, 2, 4, 6, 8 Gy) and CAP jet treatment (0, 60, 180, 240, 300 s). CAP jet treatment showed time dependent increase in H₂O₂ and NO₂^? concentration. Cell viability assay showed potent effect of CAP jet on all three cell lines in comparison to radiation treatment, while helium gas treatment showed minimal inhibitory effect. Irradiated, CAP jet and helium gas treated cells showed loss of nucleic acid features, 788 cm^?1 and 1340 cm^?1 in Raman spectra, indicating DNA damage. Principal Component Analysis (PCA) showed distinct classification of CAP-treated and control cells, while Principal Component – Linear Discriminant Analysis (PC-LDA) based classification of Raman spectra showed ITOC-03 and HEK293 cells to be sensitive to CAP jet and radiation treatment in comparison to MCF7 cells. Collectively, cell viability assay and Raman spectroscopy have shown potent effect of CAP jet in GB-SCC and breast adenocarcinoma cells.

     

A universal sample injection system for capillary column GC using a programmed temperature vaporizer (PTV)

This article describes the use of a programmed temperature vaporizer injection system which overcomes many of the classical problems associated with other injection techniques employed in capillary GC. The system can be operated in three distinct modes.     

Dichotomic lattices and local discretization for Galois lattices

The present paper deals with supervised classification methods based on Galois lattices and decision trees. Such ordered structures require attributes discretization and it is known that, for decision trees, local discretization improves the classification performance compared with global discretization. While most literature on discretization for Galois lattices relies on global discretization, the presented work introduces a new local discretization algorithm for Galois lattices which hinges on a property of some specific lattices that we introduce as dichotomic lattices. Their properties, co-atomicity and \(\vee \)-complementarity are proved along with their links with decision trees. Finally, some quantitative and qualitative evaluations of the local discretization are proposed.     

Cost-effective radio over fiber system for multi service wireless signal

The feasibility of the simultaneous transmission of several wireless signals over a cost-effective Radio over Fiber (RoF) link is investigated. A RoF link simulation tool is presented and applied to validate the experimental results in the case of the transmission of two wireless signals, one compliant to Universal Mobile Telecommunications Service (UMTS) and one to Worldwide Interoperability for Microwave Access (WiMAX) standards. The cross-talk between the transmitted signals is showed and related to the RoF transmitter's characteristic in terms of frequency chirping. Both for uplink and downlink of the wireless signal RoF distribution system practical design aspects are finally evidenced.     

The compatibility of the cyano and alkyl chloride functions in phenylthioalkylation reactions of O-silylated enolates

The compatibility of the cyano group and of chlorides with the conditions of phenylthioalkylation O-sitylated enotates has been demonstrated.     

The vinyl chloride-carbon monoxide copolymerization

Vinyl chloride and carbon monoxide have been copolymerized in bulk. The copolymers and their products of reaction with methanol and water have been examined by i.r. and NMR spectroscopy. The carbon monoxide incorporated in these copolymers is present in

units. Polymerizations carried out at progressively higher pressure of carbon monoxide lead to lower molecular weight polymers.     

All-oxide superconductor/ferroic hybrids

This short review focuses on interface interactions in hybrid heterostructures which combine high-temperature superconductors, ferromagnets and ferroelectrics. We specifically examine two different phenomena. One of them is electric-field effects at superconductor/ferroelectric interfaces, which allow a nonvolatile, reconfigurable nanoscale modulation of superconductivity. The second phenomenon is the proximity effect at superconductor/ferromagnet interfaces. We focus in particular on the penetration of superconducting correlations into half-metal ferromagnets. For both phenomena, an overview is given on materials’ issues, fabrication techniques, physical mechanisms and related devices.