Inequalities for the moments of v-infinitely divisible laws and the characterization of probability distributions

Translated from:Problemy Ustoichivosti Stokhasticheskikh Modelei, Trudy Seminara, 1989, pp. 93–103.     

On the location parameter confidence intervals based on a random size sample from a partially known population

The problem of constructing confidence intervals of a fixed length for the location parameter based on a random size sample is considered. It is proposed to use the confidence interval $$\theta _p^* - u\sqrt p /\sigma< \theta< \theta _p^* + u\sqrt p /\sigma $$ , whereθ _p ^* is an adaptive estimator,σ ² is the Fisher information, and p^?1 is the mean of the sample size. Nonparametric bounds are given for the limit as p → 0 confidence probability. Bibliography: 5 titles.     

Inhibiting activity of complexes of urethanes with variable valency metals

Conclusions The powerful inhibiting action of complexes of variable valency metals with urethanes in the oxidation of ethylbenzene has been revealed.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, pp. 479–482, February, 1970.     

Synthesis, binding affinity, and relaxivity of target-specific MRI contrast agents

Although magnetic resonance imaging (MRI) is one of the most important imaging modalities of the central nervous system (CNS), one of the main drawbacks of MRI is its limited specificity. This can potentially be partially alleviated by target-specific contrast agents. In the present paper we describe a simple high yield synthesis of two such gadolinium-based spiperone targeted MRI contrast agents, 1a and 1b. The R₁ relaxivities of 1a and 1b were evaluated and found to be 5.94 and 8.31 mM⁻¹ s⁻¹, respectively at 9.4T, while their R₂ relaxivities at the same magnetic field were found to be 18.05 and 22.60 mM⁻¹ s⁻¹, respectively. In addition and very importantly compound 1a, which is a gadolinium-based, spiperone-targeted MRI contrast agent, was found to preserve some of the spiperone affinity toward the dopamine D2 receptor. Compounds 1a and 1b thus represent potential agents for in vitro dopamine receptor imaging using MRI in experimental models. Electronic supplementary material The online version of this article (doi:) contains supplementary material, which is available to authorized users.     

Asymptotic ɛ -admissibility of the sample variance as an estimator of the population variance

A quantitative estimate is given of the robustness of the characterization of the distribution with a density by the property of asymptotic -admissibility of the sample variance as an estimator of the population variance with a quadratic loss function.Translated from Zapiski Nauchnykh Seminarov Leningradskogo Otdeleniya Matematicheskogo Instituta im. V. A. Steklova AN SSSR, Vol. 61, pp. 75–83, 1976.     

Anti-TNF-α Compounds as a Treatment for Depression

Millions of people around the world suffer from psychiatric illnesses, causing unbearable burden and immense distress to patients and their families. Accumulating evidence suggests that inflammation may contribute to the pathophysiology of psychiatric disorders such as major depression and bipolar disorder. Copious studies have consistently shown that patients with mood disorders have increased levels of plasma tumor necrosis factor (TNF)-α. Given these findings, selective anti-TNF-α compounds were tested as a potential therapeutic strategy for mood disorders. This mini-review summarizes the results of studies that examined the mood-modulating effects of anti-TNF-α drugs.     

Two-point contact chiral distinction--a theoretical appraisal

Ab initio calculations reveal chiral distinction in two-point contact CHFCIBr dimers, with chiral distinction energy of 1.5 kJ mol-1 between the SR and SS dimers fully optimized at the MP2/6-311++G** level.     

Luminescence of Fe3+ in single crystals of LiAl5O8

We have measured the luminescent properties of single crystals of LiAl₅O₈:Fe³⁺. In addition to a zero-phonon line due to Fe³⁺ in A-sites, we have observed another sharp fluorescent line at 699.2 nm which we assign to Fe³⁺ occupying B-sites. The excitation spectrum of the B-site Fe³⁺ shows characteristics similar to those of the A-site Fe³⁺ but are also shifted towards longer wavelengths. The spectra of the single crystals are compared with those of ordered and disordered powder samples.