Nouveau precurseur de prostaglandines

We describe the stereospecific synthesis of a potential precursor of prostaglandins, starting from bicyclo(4.3.0)nonene-7,9-dione.     

Contribution a la synthese de prostaglandines

A new general method for grafting the β chain of natural Prostaglandins and homologs is proposed.     

Numerical simulation of a coupling effect on electronic states in quantum dots

Lasers operating at 1.3 μm have attracted considerable attention owing to their potential to provide efficient light sources for next-generation high-speed communication systems. InAs/GaAs quantum dots (QDs) were pointed out as a reliable low-cost way to attain this goal. However, due to the lattice mismatch, the accumulation of strain by stacking the QDs can cause dislocations that significantly degrade the performance of the lasers. In order to reduce this strain, a promising method is the use of InAs QDs embedded in InGaAs layers. The capping of the QD layer with InGaAs is able to tune the emission toward longer and controllable wave-lengths between 1.1 and 1.5 μm. In this work, using the effective-mass envelope-function theory, we investigated theoretically the optical properties of coupled InAs/GaAs strained QDs based structures emitting around 1.33 μm. The calculation was performed by the resolution of the 3D Schrödinger equation. The energy levels of confined carriers and the optical transition energy have been investigated. The oscillator strengths of this transition have been studied with and without taking into account the strain effect in the calculations. The information derived from the present study shows that the InGaAs capping layer may have profound consequences as regards the performance of an InAs/GaAs QD based laser. Based on the present results, we hope that the present work make a contribution to experimental studies of InAs/GaAs QD based structures, namely the optoelectronic applications concerning infrared and mid-infrared spectral regions as well as the solar cells.     

Nanofluid Today

Journal of Thermal Analysis and Calorimetry -     

PIV measurements of an air jet impinging on an open rotor-stator system

The current work experimentally investigates the flow characteristics of an air jet impinging on an open rotor-stator system with a low non-dimensional spacing, G?=?0.02, and with a very low aspect ratio, e/D?=?0.25. The rotational Reynolds numbers varied from $0.33\times10^5$ to $5.32\times10^5$ , while the jet Reynolds numbers ranged from 17.2?×?10³ to 43?×?10³. Particle image velocimetry (PIV) measurements were taken along the entire disk diameter in three axial planes. From the obtained PIV velocity fields, the flow statistics were computed. A recirculation flow region, which was centered at the impingement point and possessed high turbulence intensities, was observed. Local peaks in root-mean-square fluctuating velocity distributions appeared in the recirculation region and near the periphery, respectively. Proper orthogonal decomposition analysis was applied to the cases of the jet impinging on the rotor with and without rotation to reveal the coherent structures in the jet region.     

High-order Large Eddy Simulations of Confined Rotor-Stator Flows

In many engineering and industrial applications, the investigation of rotating turbulent flow is of great interest. In rotor-stator cavities, the centrifugal and Coriolis forces have a strong influence on the turbulence by producing a secondary flow in the meridian plane composed of two thin boundary layers along the disks separated by a non-viscous geostrophic core. Most numerical simulations have been performed using RANS and URANS modelling, and very few investigations have been performed using LES. This paper reports on quantitative comparisons of two high-order LES methods to predict a turbulent rotor-stator flow at the rotational Reynolds number Re(=?Ωb ²/ν)?=4 × 10⁵. The classical dynamic Smagorinsky model for the subgrid-scale stress (Germano et al., Phys Fluids A 3(7):1760–1765, 1991) is compared to a spectral vanishing viscosity technique (Séverac & Serre, J Comp Phys 226(2):1234–1255, 2007). Numerical results include both instantaneous data and post-processed statistics. The results show that both LES methods are able to accurately describe the unsteady flow structures and to satisfactorily predict mean velocities as well as Reynolds stress tensor components. A slight advantage is given to the spectral SVV approach in terms of accuracy and CPU cost. The strong improvements obtained in the present results with respect to RANS results confirm that LES is the appropriate level of modelling for flows in which fully turbulent and transition regimes are involved.     

Proteomics of cypress pollen allergens using double and triple one-dimensional electrophoresis

Italian cypress (Cupressus sempervirens, Cups) pollen causes allergic diseases in inhabitants of many of the cities surrounding the Mediterranean basin. However, allergens of Cups pollen are still poorly known. We introduce here a novel proteomic approach based on double one‐dimensional gel electrophoresis (D1‐DE) as an alternative to the 2‐DE immunoblot, for the specific IgE screening of allergenic proteins from pollen extracts. The sequential one‐dimensional combination of IEF and SDS‐PAGE associated with IgE immunoblotting allows a versatile multiplexed immunochemical analysis of selected groups of allergens by converting a single protein spot into an extended protein band. Moreover, the method appears to be valuable for MS/MS identification, without protein purification, of a new Cups pollen allergen at 43 kDa. D1‐DE immunoblotting revealed that the prevalence of IgE sensitization to this allergen belonging to the polygalacturonase (PG) family was 70% in tested French allergic patients. In subsequent triple one‐dimensional gel electrophoresis, the Cups pollen PG was shown to promote lectin‐based protein‐protein interactions. Therefore, D1‐DE could be used in routine work as a convenient alternative to 2‐DE immunoblotting for the simultaneous screening of allergenic components under identical experimental conditions, thereby saving considerable amounts of sera and allergen extracts.     

Écoulement turbulent dans une cavité rotor–stator fermée de grand rapport d'aspect

A direct numerical simulation is combined with laboratory study to describe the turbulent flow in an annular high speed rotor–stator cavity. Comparisons are made for a turbulent flow characterized by a Reynolds number $\mathit{Re}=\Omega R_2^2/\nu =9.5\times {10}^4$ in a shrouded cavity of large aspect ratio $G=(R_2?R_1)/h=18.32$, where $R_1$ and $R_2$ are the inner and outer radii of the rotating disk, and h is the inter-disk space. A close agreement is found between the computed results and the experimental data for the mean and turbulent fields.? To cite this article: S. Poncet, A. Randriamampianina, C. R. Mecanique 333 (2005).     

Three-dimensional Turbulent Boundary Layer in a Shrouded Rotating System

A thre-dimensional direct numerical simulation is combined with a laboratory study to describe the turbulent flow in an enclosed annular rotor-stator cavity characterized by a large aspect ratio G = (b − a)/h = 18.32 and a small radius ratio a/b = 0.152, where a and b are the inner and outer radii of the rotating disk and h is the interdisk spacing. The rotation rate Ω considered is equivalent to the rotational Reynolds number Re = Ωb ²/ν= 9 .5 × 10⁴ (ν the kinematic viscosity of water). This corresponds to a value at which experiment has revealed that the stator boundary layer is turbulent, whereas the rotor boundary layer is still laminar. Comparisons of the computed solution with velocity measurements have given good agreement for the mean and turbulent fields. The results enhance evidence of weak turbulence by comparing the turbulence properties with available data in the literature (Lygren and Andersson, J Fluid Mech 426:297–326, 2001). An approximately self-similar boundary layer behavior is observed along the stator. The wall-normal variations of the structural parameter and of characteristic angles confirm that this boundary layer is three-dimensional. A quadrant analysis (Kang et al., Phys Fluids 10:2315–2322, 1998) of conditionally averaged velocities shows that the asymmetries obtained are dominated by Reynolds stress-producing events in the stator boundary layer. Moreover, Case 1 vortices (with a positive wall induced velocity) are found to be the major source of generation of special strong events, in agreement with the conclusions of Lygren and Andersson (J Fluid Mech 426:297–326, 2001).