Structurally isomeric two pyridino macrocycles: complexation and structures

Pyridine-based, structurally isomeric two macrocyclic compounds displayed a remarkably different complexation nature. The cage-type compound has an ideal structure for spherical cations, especially for the NH₄⁺ ion, but the reaction with some transition metals and Ln³⁺ produced its protonated species. On the other hand, its isomer formed complexes with alkali metals and lanthanides (1:1) and also with transition metals. Some structures of the complexes were clarified by crystallographic analyses.     

Carbon dioxide fixation by microalgae photosynthesis using actual flue gas discharged from a boiler

To mitigate CO₂ discharged from thermal power plants, studies on CO₂ fixation by the photosynthesis of microalgae using actual exhaust gas have been carried out. The results are as follows.

Supplementary Observations on the Chemistry of the Alkaloids of Berberine Series and Related Compounds. III. Fluorescence Spectra of the Alkaloids of Berberine Series and Their Related Compounds

The absorption maxima of the fluorescence spectra of the berberine series alkaloids are broadly distributed between 360 and 560 mμ. The fluorescence spectra of most substances of this series are very monotonous one having a single peak, the spectra of tetrahydrocoptisine and tetrahydroepiberberine are quite exceptional and consist of two wavy bands. The introduction of the auxochrome group into the molecule of “proto” compounds causes the decreasing of the fluorescence intensity and this effect is strongest in case of transition from protoberberine to berberine. That, tetrahydropalmatine does not show the distinct fluorescence spectrum band is the only incomprehensible fact.     

A linear algorithm for the domination number of a series-parallel graph

A vertex u in an undirected graph G = (V, E) is said to dominate all its adjacent vertices and itself. A subset D of V is a dominating set in G if every vertex in G is dominated by a vertex in D, and is a minimum dominating set in G if no other dominating set in G has fewer vertices than D. The domination number of G is the cardinality of a minimum dominating set in G.The problem of determining, for a given positive integer k and an undirected graph G, whether G has a dominating set D in G satisfying ¦D¦ ≤ k, is a well-known NP-complete problem. Cockayne have presented a linear time algorithm for finding a minimum dominating set in a tree. In this paper, we will present a linear time algorithm for finding a minimum dominating set in a series-parallel graph.     

Reaction of 2-propargylphenylcarbamates with diphenyliodonium salts via Meyer-Schuster rearrangement

The syntheses of 2,3-dihydro-4-quinolones from 2-propargylphenylcarbamates by one-pot tandem process that involves Meyer-Schuster rearrangement or arylative Meyer-Schuster rearrangement/Michael addition of carbamate nitrogen to the resulting vinyl ketones have been developed. Phenylcarbamates tethering tertiary propargyl alcohols underwent arylative Meyer-Schuster rearrangement/Friedel-Crafts alkylation to produce 2,3-dihydroindenones.     

An LC method for quantifying bepridil in human plasma using 1-naphthol as the internal standard

A modified method for the quantitative determination of bepridil hydrochloride in human plasma is described. This method is unrelated to chemical methods currently in use. The mobile phase is 50 mM phosphate buffer (pH3.0)-methanol-acetonitrile-triethylamine (57:3:40:1, v/v), and the samples are fractionated on a C8-3 column (150 × 4.6 mm, 5 μm) using a flow rate of 0.9 mL/min. Bepridil was detected by UV spectroscopy at 254 nm. The retention times of bepridil and 1-naphthol were 12.6 min and 7.5 min, respectively; there was no interference originating from human plasma. We confirmed that the bepridil and 1-naphthol peaks were not influenced by the presence of 32 commercial medicines frequently co-administered with bepridil. Additionally, the concentration of bepridil in the plasma of five patients treated with bepridil for atrial fibrillation was measured. These samples were collected just before each dosage of bepridil. Their rhythm and rate control were well maintained. Trough concentrations ranged from 233.9 to 347.4 ng/mL, similar to previously reported values.     

Semiconductor diamond heater in the Kawai multianvil apparatus: an innovation to generate the lower mantle geotherm

Semiconductor diamond is considered the best heater material to generate ultra-high temperatures in a Kawai cell. In two pioneering studies, a mixture of graphite and amorphous boron (or boron carbide, B₄C) was converted to semiconductor diamond in the diamond stability field and was confirmed to generate 2000°C and 3500°C, respectively. Following these works, we synthesized a homemade boron-doped graphite block with fine machinability. With this technical breakthrough, we developed a semiconductor diamond heater in a smaller Kawai-type cell assembly. Here, we report the procedure for making machinable boron-doped graphite, and the performance of the material as a heater in a Kawai cell at 15?GPa using tungsten carbide anvils and at ～50?GPa using sintered diamond anvils. Furthermore, we present a finite element simulation of the temperature distribution generated by a semiconductor diamond heater, which is much more homogeneous than that generated by a metal heater.