Enzymatic polymerization of vinyl monomers

The possibility of using horse radish peroxidase as a catalyst for polymerization of monomers (vinylformamide and sodium vinylsulfonate) in the presence of hydrogen peroxide and 2,4-pentanedione in aqueous medium at room temperature was studied.     

Synthesis of Arylidene Derivatives of 1-Aryl-3H-pyrrol-2-ones

The aminolysis of 5-aryl-3-arylidene-3H-furan-2-ones by the action of aromatic amines leads to the formation of substituted amides of 4-oxo acids, the subsequent azacyclization of which in the presence of acetic anhydride leads to the formation of 1,5-diaryl-substituted 3-arylidene-3H-pyrrol-2-ones. The mechanism of the occurring and alternative transformations is discussed.     

Synthesis of 3-R-2-aryl-4,6-dinitroindoles and specific features of their reactions with anionic nucleophiles

Reaction of different anionic S-nucleophiles with 3-R-2-aryl-4,6-dinitroindoles led to a regiospecific nucleophilic substitution of the nitro group in position 4 with 6-NO₂ group remaining intact. The representatives of some peri-annulated polycyclic systems were synthesized on the basis of the substitution products. Dedicated to Academician V. A. Tartakovsky in honor of his 75th anniversary. Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 8, pp. 1543–1547, August, 2007.     

Diene synthesis with 2-pyrones and 2-pyridones. 31. Stereochemistry of the successive addition of two different dienophiles to 2-pyrones

The stereochemistry of the successive addition of two different dienophiles, viz., N-phenylmaleinimide and 4-phenyl-1,2,4-triazoline-3,5-dione, to 2-pyrones was studied. The configurations of the mixed adducts (bisimides) obtained were established by PMR and mass spectrometry. It is shown that in all cases the reactions proceed with the formation of mixtures of syn and anti isomers, the ratios of which depend on the positions of the methyl groups in the starting 2-pyrones.See [1] for communication 30.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1471–1476, November, 1982.     

A three‐dimensional framework of bis­[tris­(ethyl­enediamine)zinc] tetra­iodo­cadmate diiodide assisted by N—H⋯I hydrogen bonds

The title salt, [Zn(C₂N₂H₈)₃]₂[CdI₄]I₂, conventionally abbreviated [Zn(en)₃]₂[CdI₄]I₂, where en is ethyl­enediamine, contains discrete [Zn(en)₃]²⁺ cations and [CdI₄]²⁻ anions with distorted octa­hedral and nearly tetra­hedral geometries, respectively, as well as uncoordinated I⁻ ions. The cation and the free I⁻ anion lie on twofold rotation axes and the [CdI₄]²⁻ anion lies on a axis in the space group I2d. The structure exhibits numerous weak inter‐ionic hydrogen bonds of two types, viz. N—H⋯I⁻(free ion) and N—H⋯I([CdI₄]²⁻), which support the resulting three‐dimensional framework.     

Study of the acylation reaction of 2,6-dimethyl-3,5-pyridinedicarboxylic acid hydrazides

Acylation of 3-ethoxycarbonyl-2,6-dimethyl-5-pyridinecarboxylic acid hydrazide and 2,6-dimethyl-3,5-pyridinedicarboxylic acid dihydrazide using aromatic acid chlorides gave the corresponding N-aroyl hydrazides. It was found that the hydrazinolysis of 3-ethoxycarbonyl-2,6-dimethyl-5-pyridinedicarboxylic acid N-aroyl hydrazides occurred not at the ester group but as a rehydrazinolysis reaction at the dihydrazide fragment. __________ Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1834–1845, December, 2005.     

Electronic structures and spectral and acid-base properties of pyrrol-, thiophen-, and furananthrones

The IR spectra, electronic absorption and luminescence spectra, solvatochromism, and basicities of compounds of the 6H-dibenz[cd,g]indol-6-one, 6H-anthra[9,1-bc] thiophen-6-one, and 6H-anthra[9,1-bc]furan-6-one groups were studied. The interrelationship between the indicated properties and such structural factors as the 1,10-anthraquinoid structure, the presence of a -surplus heteroring, and the presence of substituents was examined.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 486–493, April, 1985.     

Silyl Modification of Biologically Active Compounds. 8. Trimethylsilyl Ethers of Hydroxyl-containing Thiazole Derivatives

Trimethylsilyl ethers of various hydroxyl-containing thiazole derivatives have been synthesized. The psychotropic activity (in vivo) and the cytotoxicity (in vitro on tumor cell lines HT-1080 and MG-22A) of these ethers and of their unsilylated precursors have been studied. It was discovered that the obtained compounds possess a sedative action. A moderate cytotoxic effect was detected for piperidine-containing thiazoles, displayed most strongly in relation to MG-22A cells.