Photodynamic activity of dibiotinylated aluminum sulfophthalocyanine in vitro and in vivo

The photodynamic activity of dibiotinylated aluminum sulfophthalocyanine was studied in vitro and in vivo. Dibiotinylated aluminum sulfophthalocyanine provided enhanced phototoxic action on OAT-75 cell monolayers as compared with the parent drug. Photodynamic therapy of mice with Ehrlich carcinoma using dibiotinylated aluminum sulfophthalocyanine (0.25 mg/kg) resulted in enhanced inhibition of tumor growth, pronounced vascular damage (thrombosis and destruction of vascular walls) and eventual tumor necrosis.     

Nuclear electric quadrupole interactions in liquids entrapped in cavities

Liquids entrapped in cavities and containing quadrupole nuclei are considered. The interaction of the quadrupole moment of a nucleus with the electric field gradient is studied. In such a system, molecules are in both rotational and translational Brownian motions which are described by the diffusion equation. Solving this equation, we show that the intra- and intermolecular nuclear quadrupole interactions are averaged to zero in cavities with the size larger than several angstroms.     

Quantum coherence dynamics of spin pairs in many-spin cluster

We consider the dynamics of a quantum coherence of two chosen spins in systems of dipolar coupled nuclear spins s=1/2 in solid. With the purpose to study this coherence we suggest two different methods. One of them uses the partial trace technique and reduced density matrix. The second method is based on the calculation the intensity of multiple quantum coherences using two-spin operator and the density matrix of the whole spin system. Results of calculations of the multiple-quantum dynamics in spin clusters of various dimensionalities are presented. It is shown that the whole density matrix method is more informative than the method based on the reduced density matrix.     

NMR method for amplification of single-spin state

Amplification of a single-spin state using nuclear magnetic resonance (NMR) techniques in a rotating frame is considered. The main aim is to investigate the efficiency of various schemes for quantum detection. Results of numerical simulation of the time dependence of individual and total nuclear polarizations for 1D, 2D, and 3D configurations of the spin systems are presented.     

Electromagnetic scattering by a homogeneous chiral obstacle in a chiral environment

Time-harmonic electromagnetic waves are scattered by a homogeneouschiral obstacle embedded in a chiral environment. The correspondingtransmission problem is reduced, via Bohren's decomposition,to an integral equation over the interface between the obstacleand the surrounding medium. This integral equation is shownto be uniquely solvable except for a discrete set of electromagneticparameters of the obstacle.     

Dynamics of multiple quantum coherences in dipole-coupling spins in solid

A perturbation method deals with dipolar coupling spins in solids is presented. As example of application the method, the multiple-quantum coherence dynamics in clusters of a linear chain of four nuclear spins and a ring of six spins coupled by dipole-dipole interaction are considered. The calculated 0Q and 2Q intensities in a linear chain of four nuclear spins and 6Q intensity in a ring of six spins vs. the duration of the preparation period agree well with the exact solutions (for linear chain of four nuclear spins) and simulation data (for linear chain of four nuclear spins and a ring of six spin).