Mass-spectrometric method of analyzing mixtures of diterpene bases from plants of the genus Aconitum

The qualitative composition of the mixture of diterpene alkaloids from the roots ofAconitum septentrionale from various growth sites has been studied. Twenty-one bases have been detected. The mass-spectrometric method of multipeak monitoring has been used for the rapid checking of the amounts of the main component and seven subsidiary components. Institute of the Chemistry of Plant Substances, Uzbek SSR Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 532–536, July–August, 1989.     

Sepaconitine — A new alkaloid from Aconitum septentrionale

The structure of a new alkaloid sepaconitine isolated from the epigeal part ofAconitum septentrionale has been established on the basis of spectral characteristics.     

2,5-Dichloro-4,4-ethylenedioxy-3-phenylsulfonyl-2-cyclopentenone in Nucleophilic Substitution and Addition Reactions

2,5-Dichloro-4,4-ethylenedioxy-3-phenylsulfonyl-2-cyclopentenone reacts with diethyl malonate potassium salt according to the Ad_NE pattern with replacement of chlorine atoms at the double C=C bond, while the reaction of the same substrate with allylcuprate is not selective, and it follows several pathways.__________Translated from Zhurnal Organicheskoi Khimii, Vol. 41, No. 4, 2005, pp. 562–566.Original Russian Text Copyright © 2005 by Ivanova, Usmanova, Miftakhov.     

Hydrogen exchange in intramolecular cycloalkylation of phenylalkanols

Hydrogen exchange in intramolecular cycloalkylation of 2-methyl-4-phenyl-2-butanol (I) and 2-methyl-5-phenyl-2-pentanol (II) in the presence of 85% D₂SO₄ has been studied. The product 1,1-dimethylindane(III) is shown to contain deuterium in both aromatic ring and polymethylene fragment, whereas 1,1-dimethyltetralin (IV) contains deuterium only in the aromatic ring. A probable mechanism of the reaction is discussed.

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2--4--2- (I) 2--5--2- (II) 85% D₂SO₄. , 1,1- (III) , 1,1- (IV) . .

     

New Guaipyridine Sesquiterpene Alkaloids from Artemisia rupestris L.

Three new guaipyridine sesquiterpene alkaloids, rupestine A, B, C ( 1 – 3 , resp.), and the new nor‐sesquiterpne alkaloid rupestine D ( 4 ) were obtained from the flowers of Artemisia rupestris L. Their structures were elucidated on the basis of sepectroscopic data and by comparison with those of the related compounds reported in the literature. In addition, the absolute configurations of 2 and 4 were determined by single‐crystal X‐ray diffraction analyses.     

Application of SSNTDs for study of boron distribution in alloys

A study of boron behavior and its distribution in boron doped iron-, nickel- and aluminum-base alloys subjected to various treatment conditions has been performed. For this purpose a technique based on the detection of ¹⁰B(n,)⁷Li reaction products with track etch detectors has been applied. High boron enrichment of grain boundaries of both iron base and ingot nickel base alloys has been observed. After hot and then cold rolling of the latter specimens boron rearrangement along with the proper deformation of the structure took place. Striation of boron in a hot rolled aluminum alloy along the rolling direction has been observed.     

Structure of acsinatine

The alkaloid acsinatine has been isolated from the roots of Aconitum leucostomum, and its structure has been established on the basis of spectral characteristics. Institute of Chemistry of Plant Substances, Academy of Sciences of the Uzbekistan Republic, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 409–411, May–June, 1993.     

Septerine and septefine — new alkaloids ofAconitum septentrionale

From the roots of Aconitum septentrionale Koelle we have isolated the new nor- and bisnorditerpenoid alkaloids septerine (1) and septefine (2), each containing a N-methylanthraniloyl fragment. Their structures have been established from IR-, mass-, and PMR-spectral results. Structure (1) for septerine has been confirmed by the formation of lycoctonine on its hydrolysis.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 89 14 75. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 225–228, March–April, 1996. Original article submitted December 25, 1995.