A new approach to the synthesis of 16-heteroprostanoids via isoxazole intermediates

Translated from Khimiya Geterotsiklicheskikh Soedinenii. Vol. 30. No. 3, pp. 424–425, March, 1994.     

Polarization experiments with the SPIN setup at the ITEP synchrotron

New experimental data on the spin-rotation parameters A and R measured for elastic π ^± p scattering in the resonance region and on the asymmetry in pC scattering at primary momenta in the range 1.35–2.02 GeV/c, as well as in quasielastic proton scattering on nuclei in the same momentum range, are summarized. All these data were recently obtained by using the proton synchrotron installed at the Institute of Theoretical and Experimental Physics (ITEP, Moscow). The spectrum and features of seven isospin-3/2 baryon resonances that form a peak in the total cross section at a c.m. energy of 1.9 GeV are analyzed on the basis of new data on the parameters A and R, and the results of this analysis are presented. The experiments surveyed in this article were performed by a collaboration of researchers from ITEP and the Petersburg Nuclear Physics Institute (PNPI, Gatchina), the ITEP-PNPI collaboration.     

Ferromagnetic material CdGeP2:Mn for spintronics

Solid solutions Cd_1?x Mn_xGeP₂ (x=0?0.19) have been synthesized and identified. In these solutions, the unit cell parameters decrease with an increase in the manganese content. The solid solution Cd_0.81Mn_0.19GeP₂ is a ferromagnet with the Curie temperature T _C ≈ 311 K. The paramagnetic moment of Mn²⁺ ions equal to 5.8 μ_B, as well as the spontaneous magnetization constituting 76% of the total magnetization of a crystal, has been determined with the use of the Langevin function. The origin of ferromagnetism in CdGeP₂:Mn is exchange mediated by charge carriers (holes). These holes are caused by cationic defects in the structure of chalcopyrite.     

N-Amino Derivatives of Condensed Imidazole Systems

The previously unknown 1-amino- and 3-aminonaphtho[1,2-d]imidazoles, 1-aminonaphtho[2,3-d]imidazole, 1-aminophenanthro[9,10-d]imidazole and the N-amino-N'-methylimidazolium picrates corresponding to them have been obtained by direct amination of a series of condensed imidazoles with O-picrylhydroxylamine. An X-ray structural investigation of 1-amino-3-methylnaphtho[1,2-d]imidazolium picrate showed that, in difference to 1-aminobenzimidazolium salts, a conformation exists in it in which the hydrogen atoms of the N-NH₂ group are directed to the side of the meso carbon atom.     

Oxidation of thiol compounds by molecular oxygen in aqueous solutions

Side self-oxidation of thiols was studied. It was found that these reactions in neutral and alkaline solutions are induced by impurities of variable-valence metals. The ability of transition metals to catalyze oxidation of thiols changes in the order Cu > Mn > Fe > Ni Co. The plot of the self-oxidation rate vs. pH passes through a maximum whose position on the pH scale depends on both the nature of metal and the structure of the thiol oxidized. For thiols having different structures, the kinetic orders in reactions catalyzed by copper ions differently vary with pH, which is apparently associated with the formation of complexes possessing different catalytic activity.     

Protein content,activity, and electrophoretic composition of the inhibitor-containing fraction of pea seeds

The amounts of protein and the activities of the proteinase (trypsin) inhibitors of 16 varieties of pea have been studied. The amount of protein ranged from 19.3 to 25.2% and the amidase activities of the trypsin inhibitors from 18 to 40.8 IU. It was found that the electrophoretic spectrum of the inhibitor-containing fraction of the pea seed protein consisted of 12–16 components with molecular masses of 14–89 kDa. Features of the electrophoretic spectrum of some varieties of pea have been established.V. F. Kuprevich Institute of Experimental Botany, Belorussian SSR Academy of Sciences, Minsk. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 243–247, March–April, 1989.     

Heterocyclic analogs of pleiadiene. 50. Sulfonation of perimidines,perimidones, and 2,3-dihydroperimidines

The action of concentrated sulfuric acid on perimidine and 2-substituted perimidines, 1,3-dimethylperimidinium perchlorate, and the 1,3-dimethyl derivatives of perimidone and 2,3-dihydroperimidine gave the 6(7)-sulfonic acids of these compounds.See [1] for communication 49.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 691–696, May, 1980.     

1-Alkoxyaziridines

The corresponding 1-alkoxyaziridines were synthesized by oxidation of methoxy-, ethoxy-, and isopropoxyamines with lead tetraacetate in the presence of 2-methyl-2-butene and 2,3-dimethyl-2-butene. The PMR spectra of the oxidation products were investigated, and the high pyramidal stability of nitrogen in these compounds was confirmed. The individual invertomers 1-alkoxy-2,2,3-trimethylaziridines were isolated by preparative gas-liquid chromatography.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1514–1519, November, 1972.The authors thank A. A. Potekhin, I. N. Somin, R. R. Kostikov, M. I. Komendantov, and M. A. Kuznetsov for their useful discussions.