Study of the reactione + e −→K + K − in the energy range1350 \leqq \sqrt s \leqq 2400 MeV

Thee ⁺ e ^?→K ⁺ K ^? cross section has been measured from about 750 events in the energy interval \(1350 \leqq \sqrt s \leqq 2400 MeV\) with the DM2 detector at DCI. TheK ^± form factor |F _F ^±| cannot be explained by the ρ, ω, ? and ρ′(1600). An additional resonant amplitude at 1650 MeV has to be added as suggested by a previous experiment.     

Composition of Lie transforms with rigorous estimates and applications to Hamiltonian perturbation theory

In this paper we exhibit a rigorous perturbation theory for nearly integrable Hamiltonian systems, based on the composition of Lie Transforms. Precisely, we first study the algorithm for the composition of Lie transforms, and provide rigorous estimates for the convergence radius and the truncation errors of the series; then we use our estimates for a particular model-example, namely a system of weakly coupled harmonic oscillators having Diophantine frequencies, and work out Nekhoroshev-like exponential estimates for the stability times.     

Radiative decay ofJ/ψ into γ π+ π−

The radiative decayJ/ψ → γ π⁺ π^? has been studied using the 8.6 millionJ/ψ produced in the DM2 experiment at the DCIe ⁺e^? storage rings at Orsay. The π⁺ π^? mass spectrum shows a cleanf ₂ (1270) signal, and the possible presence of two other states at thef ₂ (1720) andf ₄ (2030) masses. For thef ₂ (1270), the branching ratio BR(J/ψ →γf)xBR(f→π⁺ π^?) is measured to be (7.50±0.30±1.12)×10^?4, and the spin analysis prefers theJ=2 assignment, with helicity parametersx=0.83±0.06 andy=0.01±0.06. The existence of higher mass states is discussed.     

Chemical-genetic screen identifies riluzole as an enhancer of Wnt/β-catenin signaling in melanoma

To identify new protein and pharmacological regulators of Wnt/β-catenin signaling, we used a cell-based reporter assay to screen a collection of 1857 human-experienced compounds for their ability to enhance activation of the β-catenin reporter by a low concentration of WNT3A. This identified 44 unique compounds, including the FDA-approved drug riluzole, which is presently in clinical trials for treating melanoma. We found that treating melanoma cells with riluzole in?vitro enhances the ability of WNT3A to regulate gene expression, to promote pigmentation, and to decrease cell proliferation. Furthermore riluzole, like WNT3A, decreases metastases in a mouse melanoma model. Interestingly, siRNAs targeting the metabotropic glutamate receptor, GRM1, a reported indirect target of riluzole, enhance β-catenin signaling. The unexpected regulation of β-catenin signaling by both riluzole and GRM1 has implications for the future uses of this drug.     

Mikrochemie

Ohne Zusammenfassung     

Non-planar smoulder propagation governed by diffusion

The steady propagation of a thin smouldering front in a half-spacehas been considered. A suitable coordinate transformation hasallowed the region near the leading edge of the front to beexamined for both a maintained planar surface and with surfacecollapse due to material shrinkage. The change in the oxidizerconcentration for a small increment in the propagation speedfor large time and surface collapse has been determined. Theinfluence of two types of nonlinear diffusion on the shape ofthe smouldering front has been found; other cases can be dealtwith in a similar manner.     

Alpha decay of neutron-deficient isotopes with 78 ⪕ Z ⩽ 83 including the new isotopes 183, 184Pb and 188Bi

Using on-line mass separation of evaporation residues from heavy-ion-induced fusion reactions, three new isotopes were identified by their alpha decay, E_α given in keV: ¹⁸³Pb, 6715(20), ¹⁸⁴Pb, 6632(10) and ¹⁸⁸Bi, 6820(20). Half-lives were determined for ¹⁸⁴Pb, 0.55(6)s, ¹⁸⁵Pb, 4.1(3)s and ¹⁸³Tl, 0.060(15) s. The alpha branching ratios were re-measured for ^182–184Hg and ^{178, 179}Pt, the results are discussed within the framework of alpha width systematics.     

The reaction-annihilator distribution and the nonholonomic Noether theorem for lifted actions

We consider nonholonomic systems with linear, time-independent constraints subject to positional conservative active forces. We identify a distribution on the configuration manifold, that we call the reaction-annihilator distribution ℜ°, the fibers of which are the annihilators of the set of all values taken by the reaction forces on the fibers of the constraint distribution. We show that this distribution, which can be effectively computed in specific cases, plays a central role in the study of first integrals linear in the velocities of this class of nonholonomic systems. In particular we prove that, if the Lagrangian is invariant under (the lift of) a group action in the configuration manifold, then an infinitesimal generator of this action has a conserved momentum if and only if it is a section of the distribution ℜ°. Since the fibers of ℜ° contain those of the constraint distribution, this version of the nonholonomic Noether theorem accounts for more conserved momenta than what was known so far. Some examples are given.