Codes Over the p-adic Integers

We study codes over the p-adic integers and correct errors in the existing literature. We show that MDS codes exist over the p-adics for all lengths, ranks and p. We show that self-dual codes exist over the 2-adics if and only if the length is a multiple of 8 and that self-dual codes exist over the p-adics with p odd if and only if the length is 0 (mod 4) for p ≡ 3 (mod 4) and 0 (mod 2) for p ≡ 1 (mod 4).     

广义风险过程中渐近方差的非参数估计

本文对广义风险过程中的渐近方差作了非参数估计,得出并证明了两个定理,为广义风险过程中破产概率的区间估计作了理论准备．     

3,3,6,6-四甲基-9-邻氯苯基-1,8-二氧代-3,4,5,6,7,9-六氧化氧杂蒽的合成和晶体结构

标题化合物C23H25对O3Cl是由邻氯苯甲醛与5，5-二甲基1，3-环己二酮在N，N-二甲基甲酸腹中反应而得。结构通过单晶X-射线衍射法确定，其晶体属于单科晶系，空间群=1632。晶体结构用直接法解出，使用全矩阵最小二乘法对原子参数进行修正，最后的偏离因子为R=0．054，Rw一0．063。在晶体结构中，吡喃环与苯环之间的两面角为92．43°。     

Correlation between Site ll-Specific Human Serum Albumin (HSA) Binding Affinity and Murine in vivo Photosensitizing Efficacy of Some Photofrin Components

Human serum albumin (HSA) is one of the key components in human blood that may influence drug distribution. As such, it is important to know the affinity of any drug for albumin. Previously, Photofrina mixture of monomeric, dimeric and oligomeric porphyrins, has been subjected to HSA binding studies. However, due to its complex nature, binding studies on Photofrin or other hematoporphyrin derivatives with HSA are inconclusive. In this report, the binding properties of some components (dimers and trimers) of Photofrin® and the relationship between murine photosensitizing efficacy and those binding properties were investigated. The interaction of these porphyrins with HSA was investigated by direct ultrafiltration and fluorescent titration techniques with fluorescent probes such as dansyl-L-proline (DP), which is known to interact selectively with site II on HSA. Porphyrins also were tested for antitumor activity in a mouse model following intravenous administration and exposure to laser light. Together, the results suggest that the photosensitizers that were preferentially bound to site II of HSA were most effective at controlling murine tumor regrowth     

Total Synthesis of Several 8, 8",-Biflavones

8,8"-Biflavonoidsareantw0rtantclass0fbiflavonoids.Asasystematicresearchofthe8,8"-biflav0noids,wehavepreviouslyreportedthestudyonthereactionof2'-hydroxychaloneswithl2-H2SO4-DMSOsystem.'InthispaPer,thesynthesisof5,5",7,7',-tetTameth0xy-8,8"-biflavonela2,4,4",7,7"-tetramethoxy-8,8"-biflavone1b',4',4",,5,5,',7,7"-hexamethoxy-8,8"-biflav0ne1c4and4,4"-dibenZyl0xy-5,5",7,7"-tetramothoxy-8,8"-biflavoneldisreported.ThesyntheticmethodisshownintheSchemebelow.2-Hydroxyacet0phenonescondensedwithsubsti…     

SN2 reactions in the gas phase. Structure of the transition state

The alkylhalide-halide association ions, [RX₂]^? that are observed in the negative chemical ionization mass spectra of alkyl halides appear to be directly related to the corresponding S_N2 transition states in solution. ‘Frontside’ association of halide ions with bridgehead alkyl halides does not occur in our system. The Change in heats and entropies of association for the chloromethane series is consistent with delocalization in the [RX]₂^? ions.