Tunable infrared generation in KTA and applications

Noncollinear difference frequency mixing of dye laser and Nd:YAG second harmonic (fundamental) radiation from a commercial laser system is employed for the generation of 2.7–5.3 μm (1.6–1.7 μm) radiations in a flux-grown KTiOAsO₁ crystal. The generated radiation is used to scan the methane absorption in the fundamental (v ₃) and its first overtone (2v ₃) band at pressure 90 torr in a laboratory made single pass gas cell of length 33 cm.     

Highly enantioselective acylation of chlorohydrins using Amano AK lipase from P. fluorescens immobilized on silk fibroin–alginate spheres

Aromatic, allylic, and aliphatic compounds containing a chlorohydrin group were selected as substrates for the enzymatic kinetic resolution mediated by Amano AK lipase from Pseudomonas fluorescens immobilized in silk friboin-alginate spheres. Thus, the enantioselectivity of the process was sufficient for the production of the desired alcohols and acetates in good yields and high enantiomeric purities. This Letter provides a simple, cheap, and practical protocol for enantioselective synthesis of chlorohydrins and reinforces the versatility of silk fibroin as supports for heterogeneous catalysts.     

Extractive biocatalysis in the asymmetric reduction of α-alkyl, β-aryl enones by Baker’s yeast

We prepared various chiral α-alkyl, β-aryl ketones with good to excellent enantiomeric excess through the Baker’s yeast asymmetric double-bond reduction of the corresponding α,β-unsaturated substrates adsorbed onto the resin Amberlite XAD-7. This methodology was compatible with substrates bearing both electron-donating and withdrawing groups attached to the aromatic ring. Elongation of the α-alkyl substituent of the starting material strongly affected the reactivity and enantioselectivity of the reaction.     

Working group report: Heavy-ion physics and quark-gluon plasma

This is the report of Heavy Ion Physics and Quark-Gluon Plasma at WHEPP-09 which was part of Working Group-4. Discussion and work on some aspects of quark-gluon plasma believed to have created in heavy-ion collisions and in early Universe are reported.     

Direct Zincation of Functionalized Aromatics and Heterocycles by Using a Magnesium Base in the Presence of ZnCl2

A wide range of polyfunctional aryl and heteroaryl zinc reagents were efficiently prepared in THF by using (TMP)₂Mg ? 2 LiCl (TMP=2,2,6,6‐tetramethylpiperamidyl) in the presence of ZnCl₂. The possible pathways of this metalation procedure as well as possible reactive intermediates are discussed. This experimental protocol expands the tolerance of functional groups and allows an efficient zincation of sensitive heterocycles such as quinoxaline or pyrazine. The zincated arenes and heteroarenes react with various electrophiles providing the expected products in 60–95 % yield.