Synthesis and biological properties of novel structural analogs of isothiobarbamine

Russian Chemical Bulletin - Novel structural analogs of isothiobarbamine, which differ from the prototype scaffold by the substituent at position 2 of the pyrimidine heterocycle, were for the first...     

Synthesis and features of thermolysis of fluorine-containing aromatic 1-hydroxy-1-hydroperoxides and 1,1′-dihydroperoxides

Aromatic fluorine-containing 1-hydroxy-1-hydroperoxides and 1,1′-dihydroxyperoxides were obtained and their thermolysis features were studied. The fluorine atoms incorporation into the aromatic ring of 1-hydroxy-1-hydroperoxides was found to lead to their thermal stability increase. 1,1′-Dihydroxyperoxides are the less thermal stable than 1-hydroxy-1-hydroperoxides. Compared to the fluorine atoms, incorporation of fluoroalkyl groups into the aromatic ring exerts greater effect on the stability of the peroxide.     

Dynamics of molecules excited by infrared laser radiation

The CF₂HCl and CF₂Cl₂ molecules upon multiphoton excitation are investigated by the method of Raman light scattering spectroscopy at frequencies of fundamental transitions. It is demonstrated that essentially nonequilibrium energy distribution of molecules is formed in the process of excitation. Physical parameters characterizing this distribution are determined.     

Reaction of Perfluorocarbonyl Chlorides with Ethyl- and Phenylmagnesium Bromides

The structure of the products formed by the reactions of perfluoroadipoyl and perfluorocyclo-hexanedicarbonyl difluorides with ethyl- and phenylmagnesium bromides depends on the nature of the radical in the organomagnesium compound.__________Translated from Zhurnal Obshchei Khimii, Vol. 75, No. 7, 2005, pp. 1199–1201.Original Russian Text Copyright © 2005 by V. Chapurkin, Litinskii, Leont’eva, S. Chapurkin.     

Properties of Polyurethanes Prepared by Structuring Oligodienediols at Double Bonds and Hydroxyl Groups

The curing of oligodienediol with a combined system consisting of a polyisocyanate and a (meth)acrylate-containing compound, which allows it to be structured with the polyisocyanate both at the terminal hydroxyl groups and double bonds due to the (meth)acrylate component, has been studied. The effect of the concentration of the (meth)acrylate component and a peroxide initiator to the degree of cross linking and strength properties of elastomers has been revealed. It has been shown that the participation of oligomer double bonds to form a vulcanization structure, creating the effect of “healing” defects from functional heterogeneity, allows one to increase the degree of cross linking and strength properties of polyurethanes.     

Thermal decomposition of peroxide derivatives of polyfluorinatedβ-ketoesters

The thermal flow microcalorimetric method was used to determine the kinetic parameters for the thermal decomposition of peroxide derivatives of polyfluorinated-ketoesters and the decomposition products were established.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 7, pp. 1647–1650, July, 1990.     

Some Features of the Tscherniac‒Einhorn Reaction with 2-Thiouracil Derivatives

The Tscherniac–Einhorn reaction of 6-methyl and 6-(trifluoromethyl) derivatives of 2-thiouracil with N-(bromomethyl)phthalimide in under basic catalysis leads to the formation of S-amidomethylation products. When using 6-amino-2-thiouracil, decomposition of the alkylation products occurs. An in vitro study of the compounds obtained showed their lack of cytotoxicity and anti-HIV-1/2 activity.     

Synthesis of Perfluorinated Dioxo Esters from Dimethyl Perfluoroadipate

Russian Journal of Organic Chemistry -