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JPC – Journal of Planar Chromatography – Modern TLC - Use of an internal standard is proposed in this thin-layer chromatographic determination of fluconazole in tablet and capsule... 相似文献
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Kantak JB Bagade AV Mahajan SA Pawar SP Shouche YS Prabhune AA 《Applied biochemistry and biotechnology》2011,164(7):969-978
A lipolytic mesophilic fungus which produces lipase extracellularly was isolated from soil. Based on ITS1-5.8S–ITS4 region
sequences of ribosomal RNA, it was concluded that the isolate JK-1 belongs to genus Rhizopus and clades with Rhizopus oryzae. The present paper reports the screening, isolation, identification, and optimization of fermentation conditions for the
production of lipase (EC 3.1.1.3). Culture conditions were optimized, and the highest lipase production was observed in basal
medium with corn steep liquor as nitrogen source and glucose as carbon source. Maximum lipase production was observed at 72 h,
which is about 870 U/ml. Optimization of fermentation conditions resulted in 16-fold enhancement in enzyme production. 相似文献
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Amol A. Nagargoje Satish V. Akolkar Madiha M. Siddiqui Aditi V. Bagade Kisan M. Kodam Jaiprakash N. Sangshetti Manoj G. Damale Bapurao B. Shingate 《中国化学会会志》2019,66(12):1658-1665
A series of pyrazole‐incorporated monocarbonyl analogues of curcumin were synthesized via Clasien–Schimidt‐type condensation and subsequently screened for in vitro antiproliferative and antioxidant activity. The analogues 4c, 5d, 5e, 5g, 6e, and 6f showed potential activity against the MDA‐MB‐231 cell line. The synthesized analogues were also screened for their antioxidant activity. Compounds 5a , 5e , 6d, and 6f exhibit comparable radical scavenging activity with respect to the standard drug ascorbic acid. Furthermore, a molecular docking study has been conducted for 5d and 5g and suggests that these compounds have a potential to become lead molecules in drug discovery and process. 相似文献
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