Impurity-induced stabilization of Luttinger liquid in quasi-one-dimensional conductors

It is shown theoretically that the Luttinger liquid can exist in quasi-one-dimensional conductors in the presence of impurities in a form of a collection of bounded Luttinger liquids. The conclusion is based on the observation by Kane and Fisher that a local impurity potential in Luttinger liquid acts, at low energies, as an infinite barrier. This leads to a discrete spectrum of collective charge and spin density fluctuations, so that interchain hopping can be considered as a small parameter at temperatures below the minimum excitation energy of the collective modes. The results are compared with recent experimental observation of a Luttinger-liquid-like behavior in thin NbSe₃ and TaS₃ wires.     

4-(Isoindolin-5-yl)amino-4-oxobutyryl-β-alkoxyphenyl-β-alanines, new RGDF mimetics. Synthesis, affinity to fibrinogen receptors, antiaggregatory properties, and their correlation with the hydrophobicity

A new series of RGDF mimetics, derivatives of 4-(isoindolin-5-yl)amino-4-oxobutanoic acid, was synthesized. The compounds obtained inhibit efficiently the thrombocytes aggregation in experiments in vitro; their biological targets are fibrinogen receptors. The antiaggregatory activity and the affinity correlate with the hydrophobicity of the compounds.     

Adsorption of Fire Retardant from Dilute Aqueous Solutions onto Viscose Fiber

The adsorption isotherms of the product of transesterification of dimethyl methylphosphonate (ZG-2), used as fire retardant, from dilute solutions on viscose fiber were determined experimentally at various temperatures. The parameters of pore structure of the fibrous sorbent were estimated using the general equation of the theory of volume filling of micropores.     

Analysis of molecular chirality using the lattice model of spatial structure

A lattice model of the spatial structure of a molecule is suggested. A broken line is constructed to characterize atoms and molecular fragments. The line is a spiral (left or right) embracing the whole lattice containing the molecule. The mutual arrangement of molecular fragments along the broken line is described by a molecular code. The code contains all the necessary information about molecular conformation and configuration in compressed form. Comparing the codes makes it possible to evaluate the structural similarity and dissimilarity of molecules. For example, one can easily estimate the chirality level for enantiomers. Using this approach is demonstrated on various model structures. A. V. Bogatskii Physicochemical Institute, Ukrainian Academy of Sciences. Odessa State University. Translated fromZhurnal Strukturnoi Khimii, Vol. 39, No. 3, pp. 541–546, May–June, 1998. This work was supported by INTAS grant INTAS-UA 95-0060.     

DETECTION OF DNA-PSORALEN PHOTOADDUCTS in situ

Abstract— An immunological method, with the use of specific immune serum, has been developed for detection of 8-methoxypsoralen (8-MOP) photoadducts to DNA, formed in situ in cell nuclei, after combined treatment with 8MOP and UV-A irradiation (Zarçbska et al. , 1978). Lymphocytes fixed on slides or in suspension, and cryostat sections of different mammalian tissues, served as antigenic substrate, after treatment with 8-MOP and UV-A in vitro. Specific fluorescence in these substrates was detected in the nuclei after treatment with 30 ˜ 140 kJ/m² UV-A in the presence of 0.1-0.3 μg/cm² 8-MOP. PHA-stimulated-lymphocytes appeared to be the most sensitive substrate.
However, hairless mice treated with high doses of UV-A in vivo , 70 ˜ 360 kJ/m² did not reveal a specific fluorescence of epidermal nuclei, unless a high local concentration of 8-MOP was attained.
The apparent discrepancy in the level of photoadduct detection between the in vitro and in vivo treated specimens was explained by the low number of DNA-8-MOP-photoadducts formed in vivo under these experimental conditions. The relevance of these findings to the role of DNA-8-MOP-photoadducts formed during PUVA photochemotherapy is discussed.     

Invariants,singularities, and parameters of a Kerr solution source

The regularity of a basis of algebraic independent second-order invariants of the Riemann-Christoffel tensor of Kerr space-time is proved by direct calculation in a Boyer-Lindquist coordinate system.Translated from Izvestiya Vysshikh Uchebnykh Zavedenii, Fizika, No. 12, pp. 40–43, December, 1988.     

N-terminal tagging strategy for De Novo sequencing of short peptides by ESI-MS/MS and MALDI-MS/MS

The major portion of skin secretory peptidome of the European Tree frog Hyla arborea consists of short peptides from tryptophyllin family. It is known that b-ions of these peptides undergo head-to-tail cyclization, forming a ring that can open, resulting in several linear forms. As a result, the spectrum contains multiple ion series, thus complicating de novo sequencing. This was observed in the Q-TOF spectrum of one of the tryptophyllins isolated from Hyla arborea; the sequence FLPFFP-NH₂ was established by Edman degradation and counter-synthesis. Though no rearrangements were observed in FTICR-MS and MALDI-TOF/TOF spectra, both of them were not suitable for mass-spectrometry sequencing due to the low sequence coverage. To obtain full amino acid sequence by mass spectrometry, three chemical modifications to N-terminal amino moiety were applied. They include acetylation and sulfobenzoylation of N-amino group and its transformation to 2,4,6-trimethylpyridinium by interaction with 2,4,6-trimethylpyrillium tetrafluoroborate. All three reagents block scrambling and provide spectra better than the intact peptide. Unfortunately, all of them also readily react with lysine side chain. Hence, all investigated procedures can be used to improve sequencing of short peptides, while acetylation is the recommended one. It shows excellent results, and it is plain and simple to perform. This is the procedure of choice for MS-sequencing of short peptides by manual or automatic algorithms.