Synthesis and Crystal Structure of（Z）-2-Methyl-5,6-dihydrobenzo[d]thiazol-7（4H）-one O-Prop-2-yn-1-yl Oxime Derivatives

Compound(Z)-2-methyl-5,6-dihydrobenzo[d]thiazol-7(4H)-one O-prop-2-yn-1-yl oxime, C11H12N2 OS, as a synthetic precursor of cytotoxic triazoles has been prepared and characterized by NMR spectra. Meanwhile, the crystal of IV was obtained and determined by X-ray single-crystal diffraction. Crystal data: monoclinic system, space group P21/c, a = 9.725(9), b = 8.068(7), c = 14.452(13)A, β = 98.68(2)°, V = 1120.9(17)A3, Z = 4, F(000) = 464, Dc = 1.305 g/cm3, μ = 0.263 mm-1, R = 0.0457 and w R = 0.1298 for 11511 independent reflections(Rint = 0.0709) and 2289 observed ones(I 2σ(I)).