甲基丙烯酸三苯墓甲酯和甲基丙烯酸酯类的共聚物在溶液中的螺旋诱导和解旋作用

甲基丙烯酸三苯墓甲酯和甲基丙烯酸酯类的共聚物在溶液中的螺旋诱导和解旋作用陈传福，刘卫宏，陈永明，任长玉，习复（中国科学院化学研究所北京１０００８０）关键词甲基丙烯酸三苯基甲酯，甲基丙烯酸甲酯，光学活性，螺旋诱导，解旋在手性阴离子复合引发剂存在下，甲基...     

编写中学物理教学大纲的几个问题

去年八月北京师范大学各系抽调一部分教师和同学参加了附中的教学改革工作。我们参加了物理组的工作,编出了四年一贯制、文理分科的文科和理科的三套物理教学大纲。这份大纲初稿讨论的很不细致,加上我们的政治和业务水平的限制,里面一定会有好些不恰当,甚至错误的地方,现在介绍在下面,希望得到大家的指正以便加以修订。我们是怎样编写大纲的呢?首先,对过去的教学进行了检查,发现过去教学中存在严重的脱离生产实     

螺旋链聚甲基丙烯酸三苯甲酯包敷硅胶分离旋光异构体

用螺旋链聚甲基丙烯酸三苯甲酯（ＰＴｒＭＡ）包敷硅胶高效液相色谱法分离了十五对ＰＴＨ衍生氨基酸和药物旋光异构体,十四对系首次在ＰＴｒＭＡ柱上进行分离,其中十三对旋光异构体获得了分离。     

光学活性高分子的手性固定相

光学活性高分子的手性固定相陈传福,任长玉,习复（中国科学院化学研究所北京１０００８０）１前言众所周知,自然界和合成的旋光物质往往是以对映体的形式存在。例如,具有手性结构的合成与半合成药物多数为外消旋体。一般而言,含有手性中心的药物异构体,在药动力学和...     

甲基丙烯酸三苯基甲酯与甲基丙烯酸甲酯光学活性共聚物的结构特征

采用１３Ｃ－ＮＭＲ，ＩＲ及ＷＡＸＳ表征了甲基丙烯酸三苯基甲酯（ＴｒＭＡ）与甲基丙烯酸甲酯（ＭＭＡ）光学活性共聚物结构．阐明了具有单向螺旋链的光学活性共聚物组成的非均一性及其光学活性随组成变化呈ｓ型曲线的特征．     

COPOLYMERIZATION PROCESS OF TRIPHENYLMETHYL METHACRYLATE AND MMA WITH CHIRAL ANIONIC COMPLEX INITIATOR

The copolymerization process of triphenylmethyl methacrylate (TrMA) and methylmethacrylate (MMA) using chiral anionic complex initiator (-) SP-FlLi (Scheme 1) has beenstudied in toluene and THF, respectively. The copolymer obtained in toluene possessed muchhigher specific rotation than that in THF. These copolymers have shown a tendency to a random and a like alternating structure, respectively.     

HELIX SENSE-SELECTIVE COPOLYMERIZATION OF TRIPHENYLMETHYL METHACRYLATE WITH CHIRAL ANIONIC INITIATORS

Optically active copolymers of pairs of three monomers, triphenyl (methyl methacrylate)and one or two pyridyl substituted methyl methacrylate homologues, were obtained by helix-sense-selective copolymerization using complexes of organolithium with chiral ligand as anionicinitiators in toluene at low temperature. The copolymers obtained with (-)-sparteine (Sp) and(S,S)-(+)-and (R, R)-(-)-2, 3-dimethoxy-1, 4-bis (dimethylamino) butanes((+)-and (-)-DDB) complexes of organolithium showed low optical activity, but PMP complex with N, N-diphenylethyleneamine monolithium amide (PMP-DPEDA-Li) was effective in synthesizingcopolymers of high optical rotation ([α]_D~(25) about+320～1370°)which were comparable to thoseof relative homopolymers with one-handed helical structure.     

STEREOREGULARITY OF POLY (METHYL METHACRYLATE) OBTAINED WITH CHIRAL ANIONIC COMPLEX INITIATOR

The stereoregular polymerization of methyl methacrylate (MMA) have been investigatedwith chiral anionic complex initiator[FILi-(-)SP]in toluene, THF and toluene/THF [1/1(v/v)]. The tacticities of PMMAs obtained in the three solvents have been found to be mainly asyndiotactic triads(s-PMMA)with content of 72.3, 67.7 and 71.4%,respectively.