首届全国嗓音言语医学学习班在大连举办

北京嗓音研究协会等主办的首届全国嗓音言语医学学习班1981年7月12日至7月31日在大连举行。来自全国25省市自治区的耳鼻喉科医生、教师和文艺团体的喉科医生共110名,大家本着双百方针的精神,各抒己见、畅所欲言进行热烈讨论和交流。     

6,7-seco-ent-Kaurane diterpenoids from lsodon sculponeatus and their bioactivity

One new 6,7-seco-enr-kaurane diterpenoid,sculponin T(1),was isolated from the aerial parts of Isodon sculponeatus,along with four known analogs,sculponeatin J(2),sculponeatin K(3),sculponeatin C(4),and sculponeatin Q(5).Their structures were elucidated by extensive spectroscopic analysis and by comparison with data reported in the literature.Significant cytotoxic activity was observed for compound 2 against five human tumor cell lines with IC_(50) values ranging from 1.8 μmol/L to 3.3 μmol/L,and it also inhibited NO production in LPS-stimulated RAW264.7 cells,with IC_(50) value of 3.3 μmol/L.