Studies on the Physicochemical Properties, Structure and Antitumor Activity of an Oligosaccharide Homologue SnS-2 from the Root of Scrophularia ningpoensis Hemsh

An oligosaccharide homologue named SnS-2 was isolated from the root of Scrophularia ningpoensis Hemsl.SnS-2 was purified by means of gel-permeation chromatography and ion-exchange chromatography. Its physicochemical properties, including carbohydrate content and molecular weight were determined. The structure of SnS-2 was elucidated by chemical methods along with ^1H and ^13C NMR spectroscopy, including two-dimensional DQCOSY and H-detected ^1H, ^13C HMQC experiments. These results show that SnS-2 possesses a backbone consisting of terminal α-Galp-(1→, α-Galp-(1→6), α-Glcp-(1→6) and nonreducing end β-Fruf-(2→. The bioactive assay showed that it could inhibit the growth of Lewis pulmonary carcinoma implanted in mice.     

基于椭球封闭空气腔的光纤复合法布里-珀罗结构折射率传感特性研究

提出了基于微椭球型空气腔的在线型光纤复合法布里-珀罗干涉结构,并对其折射率传感特性进行了研究.椭球型空气微腔是利用光纤熔接机对实芯光子晶体光纤和单模光纤以特定的熔接参数熔接形成.用高斯光束模型和ABCD法则分析了椭球型空气腔的腔内损耗,建立了电磁场在复合法布里-珀罗干涉结构中传播的物理模型.根据腔长比值的不同,环境折射率对干涉条纹的影响有对比度调制和波长调制,主要研究了一种波长调制型复合法布里-珀罗结构折射率传感器.仿真结果表明该折射率传感器在1—1.6范围内不出现折射率转折点;实验结果表明在1.333—1.466范围内,折射率灵敏度～37.088 nm·RIU-1,分辨率约为2.69×10-5.该光纤复合法布里-珀罗结构干涉条纹对比度高、体积小、成本低,用于折射率测量可靠性高、分辨率高、无折射率拐点、温度串扰小.     

Structural Elucidation and Antitumor Activity of Polysaccharide AMP-1 from Atractylodis macrocephalae K.

ＩｎｔｒｏｄｕｃｔｉｏｎＡｔｒａｃｔｙｌｏｄｅｓｍａｃｒｏｃｅｐｈａｌａＫｏｉｄｚｉｓａｔｒａｄｉｔｉｏｎａｌＣｈｉｎｅｓｅｍｅｄｉｃｉｎｅ.Ｉｔｗａｓｒｅｐｏｒｔｅｄｔｈａｔｉｔｈａｓｔｈｅｓｅａｃｔｉｖｉｔｉｅｓ :“(1)ｉｎｖｉｇｏｒａｔｉｎｇｔｈｅｓｐｌｅｅｎａｎｄｂｅｎｅｆｉｔｉｎｇｖｉｔａｌｅｎｅｒｇｙ ;(2 )ｄｅ ｐｒｉｖｉｎｇｄａｍｐｎｅｓｓａｎｄｐｒｏｍｏｔｉｎｇｄｉｕｒｅｓｉｓ ;(3)ｓｔｒｅｎｇｔｈｅｎｉｎｇｓｕｐｅｒｆｉｃｉｅｓａｎｄａｎｔｉｐｅｒｓｐｉｒａｔｉｏｎ” .1Ｍｏｄｅｒ…     

植物多糖干凝胶的制备及其力学性能

以植物多糖淀粉、魔芋葡甘聚糖（KGM）为基材,采用物理改性及共混的方法,原料经溶胶-凝胶,冷冻干燥过程得到植物多糖干凝胶。通过正交试验,得到了制备植物多糖干凝胶的原料配方。探讨了制胶温度、搅拌时间、搅拌速率、溶液PH、预冷冻时间等因素对植物多糖干凝胶弹性、硬度的影响。采用响应曲面法对制备条件进行优化,得到的最佳制备条件为：制胶温度90℃、搅拌速率800r／min、搅拌时间70min、溶液pH-9、预冷冻时间14h、预冷冻温度-40℃、冷阱温度-50℃、真空度12．5kPa。该干凝胶的弹性、硬度分别为1．812mm和5．382N。扫描电镜的观察表明,该植物多糖干凝胶呈立体三维多孔网络结构。     

一种利用分布式传声器阵列的声源三维定位方法

为了提高噪声和混响条件下分布式传声器阵列进行声源定位的性能,提出一种利用空间稀疏性和压缩感知原理的声源三维定位方法。该方法首先通过两次离散余弦变换方式提取出声音信号特征,并用该特征来构建稀疏定位模型,以便能够综合利用语音信号的短时和长时特性,同时降低模型维数;然后利用在线字典学习技术动态调整字典,克服稀疏模型与实际信号之间的失配问题,增强稀疏定位模型的鲁棒性;进而提出一种改进的平滑l₀范数稀疏重构算法来进行声源位置解算,以提高低信噪比条件下的重构精度。仿真结果表明该方法不仅可以实现多目标定位,而且具有较强的抗噪声和抗混响能力.      

Studies on the Physicochemical Properties, Structure and Antitumor Activity of an Oligosaccharide Homologue SnS-2 from the Root of Scrophularia ningpoensis Hemsl.

Introduction Scrophularia ningpoensis Hemsl. is a well-known traditional Chinese herbal medicine that has been found to possess the abilities of 揷ooling the blood, nourishing the kidney, purging the schenic fire, clearing away heat and toxic material, profiting the throat?1 In the litera-ture, its components were also reported including alka-loid, flavone glycoside, sterol, amino acid, fatty acid, naphtha, carotene and trace elements.1 At present some other components, mainly small molecular…     

基于无芯光纤的多参数测量传感器

设计并制作了一种基于单模-无芯-单模-无芯-单模光纤结构的马赫-曾德尔传感器,可用来同时测量折射率和温度.该传感器中,两处无芯光纤充当输入、输出耦合器,中间单模光纤作为传感臂.利用有限元仿真和理论分析,确定耦合器和传感臂的最优长度为15 mm.在无芯光纤中激发出的高阶模进入单模光纤的包层传输,由于倏逝场的作用,受到环境折射率和温度的影响.选取透射谱不同干涉级次的波谷作为研究对象,实现了折射率和温度的同步测量.实验结果表明:1545 nm附近干涉谷的折射率和温度灵敏度分别为–153.89 nm/RIU(refractive index unit)和0.166 nm/℃;1570 nm附近干涉谷的折射率和温度灵敏度分别为–202.74 nm/RIU和0.183 nm/℃.该传感器在实现折射率和温度同步测量的同时,仍能保持较高灵敏度,在生物医疗等方面有着较好的应用前景.