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1.
Researchers have demonstrated that Raman spectroscopy can be used for characterization of tumor cells with excellent spatial resolution. However, performance evaluation of different algorithms in classifying multiclass of Raman spectra has not been reported yet. In this work, we present Raman spectra of nasopharyngeal carcinoma and nasopharyngeal normal cell lines. Combined with student’s t-test and several multivariate approaches, including decision tree, support vector classification, and linear discriminant analysis, our work shows that the relative content of two histological abnormality sensitive bands at 1449 and 1658 cm−1 in tumor cells is significantly different from that of normal cells (p = 0.0132), and can be a biomarker to classify these cells. This difference is confirmed by importance analyses in the decision tree model. Furthermore, performances of statistical methods are compared with one another to explore the ability in classification. Results show that the decision tree can be more capable for classification between tumorous and normal cell lines with sensitivity and specificity of 99.0% and 96.9%, respectively. Findings of this work further support our previous work and indicate that the decision tree performs more robustly in cell classification. Our work will prove helpful to the early diagnosis of nasopharyngeal carcinoma, and will indicate the decision tree to be the primary algorithm in tumor-cell classification.  相似文献   
2.
Naturally inspired evolutionary algorithms prove effectiveness when used for solving feature selection and classification problems. Artificial Bee Colony (ABC) is a relatively new swarm intelligence method. In this paper, we propose a new hybrid gene selection method, namely Genetic Bee Colony (GBC) algorithm. The proposed algorithm combines the used of a Genetic Algorithm (GA) along with Artificial Bee Colony (ABC) algorithm. The goal is to integrate the advantages of both algorithms. The proposed algorithm is applied to a microarray gene expression profile in order to select the most predictive and informative genes for cancer classification. In order to test the accuracy performance of the proposed algorithm, extensive experiments were conducted. Three binary microarray datasets are use, which include: colon, leukemia, and lung. In addition, another three multi-class microarray datasets are used, which are: SRBCT, lymphoma, and leukemia. Results of the GBC algorithm are compared with our recently proposed technique: mRMR when combined with the Artificial Bee Colony algorithm (mRMR-ABC). We also compared the combination of mRMR with GA (mRMR-GA) and Particle Swarm Optimization (mRMR-PSO) algorithms. In addition, we compared the GBC algorithm with other related algorithms that have been recently published in the literature, using all benchmark datasets. The GBC algorithm shows superior performance as it achieved the highest classification accuracy along with the lowest average number of selected genes. This proves that the GBC algorithm is a promising approach for solving the gene selection problem in both binary and multi-class cancer classification.  相似文献   
3.
A previous paper by the authors (Grigoriev and Meleshko, 2012 [4]) was devoted to group analysis of the equation for the power moment generating function of a solution of the Boltzmann kinetic equation with sources. An approach developed earlier by Grigoriev and Meleshko (1986 [2]) was employed for finding the admitted Lie group. This approach allowed to correct Nonenmacher׳s results (1984, [1]) and to perform a partial group classification of the considered equation with respect to a source function. The present paper completes this group classification by an efficient algebraic method.  相似文献   
4.
This work aims to investigate the dependence of flow classification on the Reynolds number (Re) for the wake of two staggered cylinders. The Re examined ranges from 1.5×103 to 2.0×104. The pitch ratio, P=P/d examined is 1.2–6.0 (d is the cylinder diameter), and angle (α) is 0–90°, where P is the center-to-center spacing between two cylinders and α is the angle between the incident flow and the line through the cylinder centers. Two single hotwires were used to measure simultaneously the fluctuating streamwise velocities (u) in the vortex streets generated by the two cylinders. The power spectral density functions and the Strouhal numbers were then obtained from the u signals, based on which the flow structure pattern or mode could be determined. Over two hundred configurations of two staggered cylinders have been examined for each Re. It is found that Re has an appreciable effect on the dependence of the flow mode on P and α. The observation is connected to the Re effect on the generic features of a two-cylinder wake such as flow separation, boundary layer thickness, gap flow deflection and vortex formation length.  相似文献   
5.
采用数量化理论的方法.以金银花中微量元素含量作为变量,进行了产地分类,分析结果表明,金银花按产地可分3类:新密、封丘和平邑为一类;南京为一类;昆明和桂林为一类.结果与生产实际一致.  相似文献   
6.
随着高质最CCD传感器技术的日渐成熟与广泛应用,以及许多大型巡天计划的相继实施,天体数据量极大,因此天体观测数据的自动识别、分析问题首当其冲.文章在原始测量空间使用最近邻方法(NN)研究了正常星系与类星体光谱的识别问题.正常星系和类星体属于河外天体,一般距离地球较远,其观测光谱会受到许多干扰,所以这两类天体光谱的分类在...  相似文献   
7.
传统DEA模型在数据两分(偏好与规避)的基础上考察决策单元的有效性,在某些场合不再适用,文章根据决策者的偏好将数据分为三类:规避、偏好、中性类,在此基础上构造评价相对有效性的DEA模型.相较而言,基于数据三分法的DEA模型更具一般性,利用该模型,文章考察了中国近年投入产出绩效问题.  相似文献   
8.
Asymmetric organocatalysis has been successfully incorporated in many multistep one-pot sequences to provide simple access to structurally complex target molecules in a highly stereoselective fashion. The key feature behind this success is the ability of organocatalyzed reactions to proceed efficiently in the presence of large amounts of spectator reagents. Additionally, owing to their organic nature and substoichiometric presence, organocatalysts are also expected to become innocent bystanders in subsequent transformations. In this Minireview, an easy-to-use classification and nomenclatural system that is capable of systematically and informatively describing each one-pot reaction is introduced, and selected important contributions within the field of organocatalytic one-pot reactions are reviewed according to this new system. Finally, future developments and perspectives in the field are discussed.  相似文献   
9.
约束边界与分岔参数有关的约束分岔问题,称为约束含参分岔问题.通过引入适当的变换,将约束含参分岔问题转化为新变量的非约束分岔问题,推导出了约束含参分岔问题转迁集的一般形式,结果表明只有约束分岔集受约束含参的影响,其它转迁集与不含参约束分岔的转迁集相同.以含参约束树枝分岔为例分析了此类问题的分岔分类,讨论了约束含参对分岔分类的影响.  相似文献   
10.
浙江省7个地点桃花水母的形态学分类研究   总被引:1,自引:0,他引:1  
以2003~2008年采集的浙江省宁波、杭州、温州和金华4个地区7个地点的桃花水母为研究对象,通过传统分类方法(形态特征分类),对桃花水母的伞径、触手数目和级数、主辐触手和其他触手的长度比、刺丝囊疣形状和排列、平衡囊数目和形状以及生殖腺的形状和颜色等生物特征的观察,将其定为索氏桃花水母(Craspedacusta sowerbyi),其中金华永康和温州平阳2个地点的桃花水母定为永康桃花水母亚种(C.sowerbyi yongkangensis),宁波、杭州5个地点的桃花水母为信阳桃花水母亚种(C.sowerbyi xinyangensis).  相似文献   
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