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Phase-changeable contrast agents have been proposed as a next-generation ultrasound contrast agent over conventional microbubbles given its stability, longer circulation time and ability to extravasate. Safe vaporization of nanodroplets (NDs) plays an essential role in the practical translation of ND applications in industry and medical therapy. In particular, the exposure parameters for initializing phase change as well as the site of phase change are concerned to be controlled. Compared to the traditional optical vaporization or acoustic droplet vaporization, this study exhibited the potential of using simultaneous, single burst laser and ultrasound incidence as a means of activating phase change of NDs to generate cavitation nuclei with reduced fluence and sound pressure. A theoretical model considering the laser heating, vapor cavity nucleation and growth was established, where qualitative agreement with experiment findings were found in terms of the trend of combined exposure parameters in order to achieve the same level of vaporization outcome. The results indicate that using single burst laser pulse and 10-cycle ultrasound might be sufficient to lower the exposure levels under FDA limit for laser skin exposure and ultrasound imaging. The combination of laser and ultrasound also provides temporal and spatial control of ND vaporization and cavitation nucleation without altering the sound field, which is beneficial for further safe and effective applications of phase-changeable NDs in medical, environmental, food processing and other industrial areas. 相似文献
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This paper focuses on the identification problem of Wiener nonlinear systems with non-uniform sampling. The mathematical model for the Wiener nonlinear system is established from the non-uniformly sampled input–output data. In order to solve the identification problem of the Wiener nonlinear system with the unmeasurable variables in the information vector, the gradient-based iterative algorithm is presented by replacing the unmeasurable variables with their corresponding iterative estimates. Finally, the simulation results indicate that the proposed algorithm is effective. 相似文献
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Ni Zifeng Pang Wenchao Chen Guomei Lu Peipei Qian Shanhua 《Russian Journal of Applied Chemistry》2017,90(11):1876-1882
Russian Journal of Applied Chemistry - A method of adding graphene oxide (GO) and further reinforcing by the treatment of gamma-irradiation was used to enhance the properties of ultrahigh molecular... 相似文献
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The effect of bias voltage on electron tunneling across a junction with a ferroelectric-ferromagnetic composite barrier is investigated theoretically. Because of the inversion symmetry breaking of the spontaneous ferroelectric polarization, bias voltage dependence of the electron tunneling shows significant differences between the positive bias and the negative one. The differences of spin filtering or tunnel magnetoresistance increase with the increasing absolute value of bias voltage. Such direction preferred electron tunneling is found intimately related with the unusual asymmetry of the electrical potential profile in two-phase composite barrier and provides a unique change to realize rectifying functions in spintronics. 相似文献
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The 2-step domination problem is to find a minimum vertex set D of a graph such that every vertex of the graph is either in D or at distance two from some vertex of D.In the present paper,by using a labeling method,we provide an O(m) time algorithm to solve the2-step domination problem on block graphs,a superclass of trees. 相似文献
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This paper focuses on the identification problem of Hammerstein systems with dual-rate sampling. Using the key-term separation principle, we derive a regression identification model with different input updating and output sampling rates. To solve the identification problem of the dual-rate Hammerstein systems with the unmeasurable variables in the information vector, an auxiliary model-based recursive least squares algorithm is presented by replacing the unmeasurable variables with their corresponding recursive estimates. Convergence properties of the algorithm are analyzed. Simulation results show that the proposed algorithm can estimate the parameters of a class of nonlinear systems. 相似文献
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