H2S·HOH or H2O·HSH, which is more stable in the water-hydrogen sulfide complex?

High-level ab initio calculations are carried out to study the relative stability of the two hydrogen bonded structures of water-hydrogen sulfide complex, one with water as the proton donor (A) and the other with hydrogen sulfide as the proton donor (B). The results show that structure A is considerably more stable than B at the correlated level, which is in contrast with previous results obtained from Hartree-Fock calculations.     

Solution bundle for a class of impulsive differential inclusions on Banach spaces

In this paper a class of impulsive differential inclusions is investigated. The existence of solution bundle is proved. And we also construct a nonlinear semigroup of operators on cb(E) (closed-bounded subset of E) to describe the set of attainable states.     

[Co(amp)2Cl2]2[ZnCl4]体系中两对称异构体的2D NMR研究

The two symmetrical isomers in [Co(amp)₂Cl₂]₂[ZnCl₄](amp=2-(Aminomethyl)pyridine) system were syn-thesized by general oxidation method and were separated by chromatography and recrystallization method. Their configurations were assigned by using 2D NMR techniques, particularly the NOESY NMR spectra. Solvent used was Me₂SO-d₆ with the central peak of the CD₃ septet as the reference ( ₁₃C,δ 39.37; ₁H,δ 2.49 relative to SiMe₄). Cation exchange media used was Dowex 50Wx 2(H⁺ form, 200～400mesh; Biorad).     

赖氨酸-Ag反应机理的研究

The interaction of silver(Ⅰ) ion with lysine has been investigated by UV-Vis, fluorescent spectra and electrophoresis method. The effect of pH medium and multicomponent concentration on interaction of lysine-silver has also been studied. Lysine-silver system showed maximum absorbance at 239 nm and 448 nm. Lysine showed fluorescence. The fluorescence excitation wavelength was about 356.6 nm (fluorescence emission wavelength was about 438.6 nm). When the reaction of silver(Ⅰ) ion with lysine happened, fluorescence was quenching. Lysine-silver system carried negative charge, and the electrokinetic potential of double electrode layer was -2.35×10^-4 V.     

3-氟-6-碘吡嗪-2-羧酸甲酯的合成及晶体结构

以3-氨基吡嗪-2-羧酸为原料，经酯化反应、亲电反应和重氮化反应合成了3-氟-6-碘吡嗪-2-羧酸甲酯（1），总收率62.34%，其结构经¹H NMR、¹³C NMR和MS确证，用X-单晶衍射法测定了化合物的晶体结构。结果表明：1（CCDC: 1986368）属单斜晶系，空间群C2/c，晶胞参数a=17.6566(5) Å, b=4.74850(10) Å，c=19.6368(6) Å，β=95.6540(10)°，V=1638.39(8) ų，Z=8，R_gt(F)=0.0173，wR_ref(F²)=0.0465，F(000)=1056，μ=3.885 mm^-1。      

Carbene-catalyzed enantioselective annulation of dinucleophilic hydrazones and bromoenals for access to aryl-dihydropyridazinones and related drugs

4,5-Dihydropyridazinones bearing an aryl substituent at the C6-position are important motifs in drug molecules. Herein, we developed an efficient protocol to access aryl-dihydropyridazinone molecules via carbene-catalyzed asymmetric annulation between dinucleophilic arylidene hydrazones and bromoenals. Key steps in this reaction include polarity-inversion of aryl aldehyde-derived hydrazones followed by chemo-selective reaction with enal-derived α,β-unsaturated acyl azolium intermediates. The aryl-dihydropyridazinone products accessed by our protocol can be readily transformed into drugs and bioactive molecules.

Polarity inversion of arylidene hydrazones to react with bromoenals via carbene organic catalysis is disclosed. The reaction enantioselectively affords 6-aryl-4,5-dihydropyridazinones and related drugs with proven commercial applications.     

分裂的正则Hom-Leibniz-Rinehart代数

作为Hom-Leibniz代数胚的代数类比, 本文引入Hom-Leibniz-Rinehart代数的概念. 证明了分裂的正则Hom-Leibniz-Rinehart代数$L$写成$L=U+\sum_{\gamma}I_\gamma$, 其中$U$为极大交换子代数$H$的子空间和$I_\gamma$为$L$的理想, 若$[\gamma]\neq[d]$, 满足$[I_\gamma, I_d]=0$. 随后分别发展了分裂Hom-Leibniz-Rinehart代数的根和权的连通技术.最后研究了紧致的正则Hom-Leibniz-Rinehart代数的结构.     

On the order of a class of meromorphic functions

This paper proves the following result: Letf(z) be a meromorphic function in thez-plane with a deficient value, and δ(θ _k )(k=1,2, ...,q;0≤θ ₁<θ₂<...<θ _q<θ _q+1=θ ₁+2π) beq rays (1≤q<∞) starting at the origin, and letn≥3 be an integer such that for any given positive numberε,0<ε<π/2, $$\overline {\mathop {\lim }\limits_{r \to \infty } } \frac{{\log ^ + n\left\{ { \cup _{k = 1}^q \Omega \left( {\theta _k + \varepsilon ,\theta _{k + 1} - \varepsilon ,r} \right),f\prime f^n = 1} \right\}}}{{\log r}} \leqslant v< \infty ,$$ whereΝ is a constant independent ofε. IfΜ<∞, then we have $$\lambda \leqslant \frac{\pi }{\omega } + v,$$ whereΜ andλ denote the lower order and order off(z), respectively,Ω=minθ _k+1 ?θ _k ;1≤k≤q, andn(E, f=a) is the number of zeros off(z)?a inE with multiple zeros being counted with their multiplicities.     

沙蚕毒系化合物的结构与生物活性关系

用ＭＮＤＯ－ＰＭ３方法对沙蚕毒系化合物二氢沙蚕毒，硫氰酸酯，巴丹，杀虫单及其异构件的几何构型进行了全自由度优化，并计算了其电子结构，讨论了生物活性与几何构型和电了结构的关系。     

Indium-mediated Facile Synthesis of （6-Chloropyridine-3-yl）methyl Heterocyclic Thioether Derivatives in Aqueous Media

A series of substituted (6-chloropyridine-3-yl)methyl heterocyclic thioether derivatives were prepared by indium mediating in water. The preliminary biological tests showed that compound 3d exhibited good antiviral activity.