Fractional Fokker-Planck Equation with Space and Time Dependent Drift and Diffusion

In this paper, we aim to answer the question proposed by Magdziarz (Stoch. Proc. Appl. 119:3238?C3252, 2009), i.e. we investigate the solution of an anomalous diffusion equation with time and space dependent force and diffusion coefficient. First, we try to find the stochastic representation of this equation, which means the PDF of this stochastic process is rightly the solution of the equation we aim to solve. Then, we also simulate the sample paths of the stochastic process. At last, taking advantage of the stochastic representation method, we employed Monte Carlo method to approximate the solution of the mentioned equation.     

原位合成H2O2在水处理技术中的应用研究进展

从过氧化氢(H₂O₂)的原位生成技术角度总结了近年来利用原位合成H₂O₂处理水中污染物的研究,分析了当前可充当氢源材料的种类及不同的氢源材料对于提高H₂O₂产率的影响,以及不同的催化剂材料和催化反应环境提高H₂O₂利用率对污染处理效果的影响因素,并对原位合成H₂O₂在水处理领域中面临的挑战和发展前景做了展望,从而为该技术的大规模应用提供指导和借鉴。     

A novel method for the sensitive detection of mutant proteins using a covalent-bonding tube-based proximity ligation assay

Tumorigenesis is the cumulative result of multiple gene mutations. The mutant proteins that are expressed by mutant genes in cancer cells are secreted into the blood and are useful biomarkers for the early diagnosis of cancer. However, some difficulties exist; for example, the same gene will express different protein mutants in different patients, and early tumors secrete only small amounts of mutant protein. Thus, the presence of mutant proteins in plasma has not previously been exploited for the early diagnosis of cancer. Proximity ligation assay is a protein-detection method that has been developed in recent years and has been widely used because of its high sensitivity. However, this approach still suffers from some shortcomings that should be addressed. In this paper, we develop a covalent-bonding tube-based proximity ligation assay (TB-PLA). The limit of detection of TB-PLA for 0.001 pM, and the method exhibited a broad dynamic range of up to seven orders of magnitude. Furthermore, we coupled the conformation-specific antibody PAb240 of p53 mutants to PCR tubes for TB-PLA. The assay was capable of detecting an approximately 500-fold lower concentration of mutant p53 in serum compared with sandwich ELISA. Thus, we demonstrate TB-PLA to be a highly sensitive and effective approach that is suitable for the early clinical diagnosis of cancer using the conformation-specific antibodies of protein mutants.     

基于ACARS的飞机实时监控系统研究

为实现对飞机运行状况的实时监控,提出利用ACARS空地数据链下载的实时维护数据,结合飞机维修技术文档以及历史维护经验来建立飞机实时监控系统,以期快速准确地诊断故障．该系统有利于地面维护人员实时掌握飞机及发动机的运行状态信息,尽早地发现飞机故障,在飞机落地前准备故障解决方案,提高维修水平和排故效率．     

新老混凝土粘结的抗压强度塑性极限分析

对新老混凝土粘结试块进行了抗压强度研究,发现新老混凝土粘结在竖向受压情况下,其抗压强度远低于整浇混凝土的抗压强度.因此,对新老混凝土粘结试块的竖向抗压强度进行相关理论分析,并根据试验,提出了新老混凝土粘结的受压破坏机构;又利用塑性极限分析中的上限定理,得到了新老混凝土粘结抗压强度的理论解.对比理论解与试验值,发现理论解高于试验值,在详细分析原因后,对理论解进行了相应修正.     

一种新的红外脉冲热成像后处理方法

脉冲热成像技术作为一种新兴的无损检测技术已被广泛应用于红外领域,然而由于试样表面加热不均匀及表面发射率低导致的红外图像对比度低、噪声大等问题给缺陷的检测带来困难。本文基于长脉冲热成像技术对碳纤维增强塑料(carbon fiber reinforced polymer,CFRP)板和304不锈钢进行了无损检测研究,提出了比温度的图像后处理方法。该方法对温度序列图像的每一帧图像与前一帧图像进行作商的后处理操作,得到比温度的图像序列。从比温度序列中获取信噪比最大的图像,以进行缺陷识别和缺陷定量。结果表明,与此前的方法相比,该方法显著提高了图像的信噪比,更有利于检测更深、更小的缺陷,相比原始图像,信噪比提高了近98.46%。将该方法与半高全宽法相结合,对试样的尺寸进行定量检测。通过仿真和实验验证,该方法具有良好的鲁棒性,显著降低了缺陷尺寸定量的误差,该方法可作为一种有效的红外图像后处理及缺陷尺寸定量方法。     

基于保守决策偏好的犹豫模糊余弦优化投影决策方法

针对犹豫模糊信息下的多属性决策问题,提出了余弦优化投影方法,将投影夹角定义为决策者的风险偏好,并设置了态度参数用于调节决策者的心理变化,通过灵活描述决策者的保守心理,改进了投影法仅考虑投影长度的不足,使决策者可通过投影长度和投影夹角对备选方案进行综合判断。算例验证了方法的合理性和可行性。     

离子色谱的抑制系统及相关技术的发展

抑制系统是抑制型(双柱型)离子色谱系统极为重要的一个组成部分,也是离子色谱有别于其它类型的液相色谱的最重要特点之一。抑制器的发展经历了多个发展时期,而目前商品化的离子色谱仪亦分别采用不同形式的抑制手段。近年来,还发展了一些特殊的辅助抑制器,如接在抑制器后面CO2除去装置,用于提高被测离子的信号或进一步降低背景电导值。