基于聚间苯二胺为受体的UC-FRET传感器检测凝血酶

本文以上转换发光材料(UCPs)为供体,聚间苯二胺(PMPD)为受体,构建了基于荧光共振能量转移(FRET)的传感平台,并将其用于凝血酶的检测。一定浓度的PMPD加入到标记单链DNA的UCPs体系中,对上转换发光的猝灭效率可以达到70%。当加入浓度在0.2~5.0nmol/L范围内的目标物凝血酶时,其荧光恢复程度与浓度呈线性关系,检出限为0.18nmol/L。PMPD因其良好的水溶性、荧光猝灭能力及免标记的特点为基于FRET技术的生物样品检测提供了新的平台。     

Origin 8.5在亥姆赫兹线圈磁场测量实验数据处理中的应用

与传统的人工处理实验数据相比,Origin8.5软件处理实验数据具有方便快捷、直观、精度高等特点。文中通过使用Origin8.5软件处理亥姆赫兹线圈测磁场实验的数据,详细介绍了二维绘图、三维绘图以及非线性曲线拟合的过程,结果表明使用Origin8.5软件处理实验数据能有效的减少人工处理带来的误差。     

复方排铅口服液治疗铅高婴幼儿166例

用已经过动物实验或临床试验证实有排铅、提高免疫功能、提高智力和强身健体作用的维生素C、维生素B1、氨基酸和有机锌、Ge-132等配成的复方排铅口服液,治疗经发铅检查铅高的婴幼儿166例,疗程1－2个月,显效率65.1％、总有效率95.8％,临床疗效比较理想。     

All-fiber linearly polarized laser oscillator by fiber coiling loss control

In this paper,we demonstrate an all-fiber linearly polarized fiber laser oscillator.The single polarization of the oscillator is achieved through the careful designing of the active fiber coiling.The relationship between fiber coiling diameter and polarization extinction ratio and optical efficiency is studied,whose results lead to an optimized system.The thermal management of the oscillator is also refined,which allows the oscillator to reach a maximum output power of44.1 W with an optical-to-optical efficiency of 57.9%.A high average polarization extinction ratio of 21.6 d B is achieved during a 2-hour stability test.The oscillator also owns a narrow 3-d B bandwidth of 0.1 nm,as well as near-diffraction-limit beam quality of M~2~ 1.14.     

线性麦芽糊精聚合物功能化Fe3O4纳米复合物药物载体的合成和应用

采用共沉淀法制备得到了线性麦芽糊精聚合物功能化的Fe₃O₄磁性纳米粒子(LM-SP-MNPs),通过傅里叶变换红外光谱、透射电子显微镜、热重分析等技术对其结构、形貌进行了表征。 其粒径大小为(12±2) nm。 选取抗癌药物盐酸阿霉素(DOX)作为模型药物,运用荧光光谱法研究了LM-SP-MNPs的载药性能和释放行为,探讨了pH值对LM-SP-MNPs药物释放性能的影响。 最适pH条件下,LM-SP-MNPs对盐酸阿霉素的最大吸附量约为357.1 mg/g,吸附等温线符合Freundlich等温吸附模型。 LM-SP-MNPs与盐酸阿霉素的复合物(DOX@LM-SP-MNPs),在37 ℃的条件下药物在酸性条件下的释放效率大于中性条件。 pH=5.3时,盐酸阿霉素在7 h内的累积释放率为26.9%。 此外,细胞毒性试验表明,LM-SP-MNPs具有良好的生物相容性,而DOX@LM-SP-MNPs和肝癌细胞共培养后可以明显杀死HepG2肝癌细胞。     

坡矩阵的Cline逆

研究了坡矩阵的广义逆. 首先引入坡矩阵的Cline逆和Drazin逆, 运用坡矩阵的性质证明任意坡矩阵都有Drazin逆, 从而得出任意坡矩阵都有Cline逆,并且是唯一的. 进一步,如果A 存在,那么AC等于A . 最后,给出AC的一些性质.     

亚BCI-代数的$(\alpha,\beta)$-软理想

首先将软集的参数集赋予亚BCI-代数, 给出了亚BCI-代数的$(\alpha,\beta)$-软理想的概念.当$U=[0,1], \alpha=U, \beta=\phi$时,相应地就得到了亚BCI-代数的犹豫模糊理想的概念.研究了亚BCI-代数的$(\alpha,\beta)$-软理想的一些重要性质.最后讨论了亚BCI-代数的$(\alpha,\beta)$-软理想的同态像和原像的性质.     

亚BCI-代数的并代数北大核心

提出了任意一族亚BCI-代数的并代数、软集在一族亚BCI-代数的并代数上的扩展交等新概念。研究了亚BCI-代数的子结构的可并性,逆可并性以及在并代数上的一系列基本性质。同时还讨论了亚BCI-代数中新型软子结构在并代数上的基本性质。     

Fiber core mode leakage induced by refractive index variation in high-power fiber laser

This paper presents an investigation of specific optical fiber core mode leakage behavior that occurs in high-power double-clad fiber lasers as a result of thermally-induced refractive index variations. A model of the power transfer between the core modes and the cladding modes during thermally-induced refractive index variations is established based on the mode coupling theory. The results of numerical simulations based on actual laser parameters are presented. Experimental measurements were also carried out, the results showed good agreement with the corresponding simulation results.     

Internal Features of Fiber Fuse in a Yb-Doped Double-Clad Fiber at 3 kW

We study internal features of fiber fuse in a Yb-doped double-clad fiber. The samples of fiber fuse are acquired at the power level of 3 kW in an all-fiber forward-pumped master oscillator power amplifier configuration fiber laser that is built specially for fiber fuse analyses. At this high power level, drastic refractive-index redistribution arises in an expended high refractive index area around the bullet-shaped voids of fiber fuse. Electron spin resonance analyses on post-fiber-fuse samples of the Yb-doped double-clad fiber indicate rising Frenkel defect concentration, meanwhile showing a new resonance center that is different from the ones of the Ge-doped fibers studied previously. This new resonance center probably suggests the generation of Al-oxygen hole center, a kind of defect formed during the catastrophic fuse process.