Thermal evolution of inverted basins: Constraints from apatite fission track thermochronology in the Cuyo Basin, Argentine Precordillera

Apatite fission track thermochronology (AFTT) was applied to derive the thermal history of formation and inversion of the oil-bearing Triassic–Cretaceous Cuyo Basin, Argentine Precordillera. The obtained central fission track ages range from 13 to 163 Ma, and the mean track lengths from 8.2 to . Based on the integration of AFTT, stratigraphic and structural data, five evolutionary phases are here proposed for the studied area: I—Late Permian cooling related to the extrusion of basement volcanics, and initial extensional regime responsible for the Cuyo Basin formation, II—Triassic–Jurassic heating linked with the filling, and consequent burial, of the Cuyo Basin, III—Jurassic–Paleogene tectonic stabilization, IV—Early Miocene heating related to the load of foreland sedimentation, V—Late Miocene rapid cooling related to the Cuyo Basin inversion. During the Late Miocene, rock units formed in different crustal levels were juxtaposed through thrust, reverse and normal faulting, resulting in contrasting old and very young central fission track ages in closely spaced samples.     

Pseudo real closed fields,pseudo p-adically closed fields and NTP2

The main result of this paper is a positive answer to the Conjecture 5.1 of [14] by A. Chernikov, I. Kaplan and P. Simon: If M is a PRC field, then $Th(M)$ is NTP₂ if and only if M is bounded. In the case of PpC fields, we prove that if M is a bounded PpC field, then $Th(M)$ is NTP₂. We also generalize this result to obtain that, if M is a bounded PRC or PpC field with exactly n orders or p-adic valuations respectively, then $Th(M)$ is strong of burden n. This also allows us to explicitly compute the burden of types, and to describe forking.     

安第斯病毒抑制肽的优化设计

安第斯病毒是汉坦病毒的一种,能引起汉坦病毒肺综合征,严重威胁人类的健康和生命安全,但目前尚缺乏有效的治疗办法,病毒抑制肽具有潜在的应用价值。本文利用多肽分子整体描述符,对一组安第斯病毒抑制肽进行定量构效关系(QSAR)研究,建立模型;并以模型为指导对多肽进行优化设计,以进一步提高其活性。结果表明,基于遗传算法-偏最小二乘算法建立的QSAR模型显示了较好的预测能力(R20.80,Q2ext0.58);依据模型设计出一组具有较高预测活性的多肽,为高活性抗病毒多肽的合成和实验验证打下了基础。