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72.
烟草植物富含优质蛋白质和生物碱,具有很高的药用价值。对近年来烟草植物在有机医药、农药方面的应用进行了总结,对烟草的应用前景进行了展望。 相似文献
73.
R. E. Bell 《International journal of environmental analytical chemistry》2013,93(3-4):219-232
Abstract An automated two-stage thermal desorption technique has been developed for the determination of airborne nicotine. Pumped samples are collected on adsorbent tubes and analysed by capillary gas chromatography using flame ionisation detection. The preconcentration effect of the adsorbent compared to solvent trapping or solvent desorption methods permits shorter sampling times and precludes the need for a selective detector. By use of a basic program all exposure volumes and component details are entered into a method run table and after analysis exposure levels are automatically calculated and printed in report form by the data handling system. Consequently a large throughput samples may be analysed automatically and efficiently with minimal analyst involvement or sample preparation. The technique described was originally developed to sample airborne nicotine in workplace environments where tobacco is processed. Comparison between this technique and the standard NIOSH method for airborne nicotine is discussed. 相似文献
74.
Ala A. Alhusban Alaa M. Hammad Lujain F. Alzaghari Aliaa I. Shallan Khaldoun Shnewer 《Biomedical chromatography : BMC》2023,37(1):e5513
Tobacco smoking is a preventable main cause of fatal diseases. Accurate measurements of the effects it has on neurotransmitters are essential in developing new strategies for smoking cessation. Moreover, measurements of neurotransmitter levels can aid in developing drugs that counteract the effects of smoking. The aim of this study is to develop and validate a fast, simultaneous and sensitive method for measuring the levels of neurotransmitters in rat brain after the exposure of tobacco cigarettes. The selected neurotransmitters include dopamine, GABA, serotonin, glutamine and glutamate. The method is based on high-performance liquid chromatography–tandem mass spectrometry. Chromatographic separation was achieved within 3 min using a Zorbax SB C18 column (3.0 × 100 mm, 1.8 μm particle size). The mobile phase consisted of HPLC-grade water and acetonitrile each containing 0.3% heptafluorobutyric acid and 0.5% formic acid at gradient conditions. The linear range was 0.015–0.07, 825–7,218, 140–520, 63.42–160.75 and 38.25 × 103 to 110.35 × 103 ng/ml for dopamine, GABA, serotonin, glutamine and glutamate, respectively. Inter- and intra-run accuracy were in the range 97.82–103.37% with a precision (CV%) of ≤0.90%. The results revealed that 4 weeks of cigarette exposure significantly increased neurotransmitter levels after exposure to tobacco cigarettes in various brain regions, including the hippocampus and the amygdala. This increase in neurotransmitters levels may in turn activate the nicotine dependence pathway. 相似文献