Ionic conductivity and compatibility studies of blends of poly(methyl methacrylate) and poly(propylene glycol) complexed with LICF3SO3

Stable to atmospheric moisture, adhesive and transparent polymer electrolytes have been prepared by blending poly(methyl methacrylate) (PMMA) with poly(propylene glycol)-425/LiCF₃SO₃ complexes. The blending of the polymers has been achieved by a method developed in our laboratory: free radical polymerization of methylmethacrylate in the polyether/salt matrix. A series of polymer blend complexes varying in PMMA content (up to 20% by weight) and oxygen/metal ratios (25, 16, and 8) have been synthesized and their properties studied. All the samples prepared in this study were found to be optically clear unlike the higher molecular weight poly(propylene glycol)-2000 (PPG-2000) system which required a minimum salt concentration to compatibilize a specific amount of PMMA with PPG. The mechanisms by which the salt holds the otherwise incompatible polymers together in a single phase have been investigated by FT-IR. Our studies show a weak coupling of the ether oxygens in the PPG with the ester groups of the PMMA through the lithium cations. Discrete changes has been observed in the FT-IR spectrum of PMMA when doped with the lithium salt hitherto unnoticed with other dopants. Gel permeation chromatography results of the PMMA samples isolated from the solid electrolytes indicate the molecular weight to vary between 43000 and 121000 with relatively narrow distributions, 1.6?2.0. The ionic conductivities of the polymer blend electrolytes were fairly high (10^?5 S/cm) at room temperature. The PMMA neither significantly influenced the T_g of the blend complexes nor effected the ionic conductivities drastically. The ionic conductivity as a function of temperature followed the empirical Vogel-Tammann-Fulcher equation. The blending of PMMA with PPG/LiCF₃SO₃ complexes was found to impart good adhesiveness to the solid electrolytes while making them stable to atmospheric moisture. © 1992 John Wiley & Sons, Inc.     

嵌入式系统抗电磁干扰体系研究与实践

针对嵌入式工业过程产品面临的复杂电磁环境,通过分析研究电磁干扰源的信号特征,探讨了抗电磁干扰的应对措施,提出了嵌入式系统产品设计时应采取的层次化的防护体系结构。在抗电磁干扰体系中,CPU及周边电路为核心,所有外部端口信号都要隔离后接入,需采取吸收、泄放、过滤等措施预先进行干扰信号衰减,防止其损坏元件,突破防护体系。结合所提出抗干扰体系结构,通过具体案例详细说明了其实现的方法。经型式试验结果和现场应用表明,所提出抗电磁干扰体系的效果良好。     

Application of thermal analysis in study of binary mixtures with metformin

Thermal analysis is an essential analytical tool in development of new formulations as well as to study the interaction between drugs and excipients. This work aims to investigate the possible interactions between metformin and excipients as microcrystalline cellulose (Microcel MC101®), starch sodium glycolate (Explosol®), sodium croscarmellose (Explosel®), PVP K30, magnesium stearate, starch and lactose, usually employed in pharmaceutical products. TG, DSC and DTA techniques were used for the thermal characterization to track if the thermal properties of the drug substance were modified in the mixture. Disregard of the starch and lactose systems, no changes in thermal behavior of mixtures were found. Thermogravimetric studies (TG) of metformin and its binary mixtures showed different thermal behavior.     

Enhanced blood compatibility of polyurethane functionalized with sulfobetaine

The purpose of this work is to develop a biocompatible polyurethane surface by the tailoring of sulfobetaine. The polyurethane film was first grafted polymerization with acrylic acid by ozonization, followed by immobilizing sulfobetaine via two routes: (i) synthesize primary amine group terminated sulfobetaine and then couple onto the surface of polyurethane using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC); (ii) couple the primary amine group terminated tertiary amine onto the surface of polyurethane primarily using EDC and then form sulfobetaine through a ring-opening reaction between tertiary amine and 1,3-propanesultone (PS). The reaction process was monitored with attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) and X-ray photoelectron spectroscopy (XPS). The blood compatibility was evaluated by a hemolytic test and platelet-rich plasma (PRP) adhesion experiment. Little hemolysis took place on the surface of polyurethane grafted with sulfobetaine. Platelets adhering on the surface of grafted polyurethane decreased greatly as compared to the original after 1 and 3h of incubation with PRP.     

Recent advances and future trends in molecularly imprinted polymers-based sample preparation

Molecular imprinting technology is a well-established technique for the obtainment of tailor-made polymers, so-called molecularly imprinted polymers, with a predetermined selectivity towards a target analyte or structurally related compounds. Accordingly, molecularly imprinted polymers are considered excellent materials for sample preparation providing unprecedented selectivity to analytical methods. However, the use of molecularly imprinted polymers in sample preparation still presents some shortcomings derived from the synthesis procedure itself limiting its general applicability. In this regard, molecularly imprinted polymers use to display binding sites heterogeneity and slow diffusion mass transfer of analytes to the imprinted sites affecting their overall performance. Besides, the performance of molecularly imprinted polymers in organic solvents is excellent, but their selective binding ability in aqueous media is considerably reduced. Accordingly, the present review pretends to provide an updated overview of the recent advances and trends of molecularly imprinted polymers-based extraction, focusing on those strategies proposed for the improvement of mass transfer and selective recognition in aqueous media. Besides, with the progressive implementation of Green Chemistry principles, the different steps and strategies for the preparation of molecularly imprinted polymers are reviewed from a green perspective.     

南中国海“G-Argo”声学浮标目标探测能力分析*

“G-Argo” 水下声学浮标作为一种新型的无动力无人移动观测平台,具备对海上目标广域、长时、隐蔽探测功能,是“透明海洋”工程立体观测系统的重要组成部分。本文通过在现有海洋环境观测浮标平台基础上,进行声学系统电磁兼容性优化设计,减小浮标平台对声学系统的电磁干扰,研制出具有目标探测能力的“G-Argo”水下声学浮标平台。并于2018年5月,在南海海区组织了多台水下声学浮标探测性能验证试验,试验结果表明,深海良好水文条件下,“G-Argo”水下声学浮标对航速10kn的配合试验船目标最远探测距离大于11km,对航速6.4kn的工程船目标最远探测距离大于42.8km,对航速12kn的集装箱船目标最远探测距离大于15.8km,对航速14.5kn的集装箱船目标最远探测距离大于24km。     

理性亚格子建模的实践与反思

亚格子建模是大涡模拟中的核心问题之一.理性亚格子建模的初衷是为尽量去除建模过程中的经验和唯象的成分,让建模过程中的每一步都在物理和数学上有迹可循.根据理性亚格子建模的理论已经发展出一系列不依赖经验常数和唯象模型的亚格子模型,但在实际问题中的效果却仍有不足,从而引发了近年来对亚格子建模思想本身的反思.本文回顾已有的研究和新的进展,目标是对未来的大涡模拟给出理性且自洽的理论指导.     

Detection of Incompatible Properties in a Double-Slit Experiment

In this work we show that, within the framework of double-slit experiment, it is possible to ascertain simultaneously more incompatible properties together with the measurement of the position of the final impact-point. A wide family of solutions is concretely found and an ideal experiment realizing such a detection is designed, relatively to the detection of two incompatible properties. In the case of three incompatible properties, general conditions for the existence of solutions are singled out and a particular family of solutions is provided.     

硅表面CS/BSA复合微图形的制备及表征

采用微加工方法在硅表面成功地制备出壳聚糖/牛血清白蛋白(CS/BSA)复合微图形. 借助光镜和荧光显微镜对复合微图形进行形貌分析. 利用大肠杆菌和白色葡萄球菌定量考察了CS/BSA复合微图形的抗菌性能, 结果表明, 硅表面沟槽交叉状CS/BSA复合微图形对两种细菌都具有较好的抗菌效果. 通过MC3T3-E成骨细胞培养考察了复合微图形的细胞相容性, 结果表明, CS/BSA复合微图形对于细胞的生长方向具有较强的诱导性, 可促进细胞在材料表面的黏附、铺展及增殖分化. 结果表明, 采用微转移模塑法制备的CS/BSA复合微图形具有较好的抗菌性和细胞相容性.