青春期多囊卵巢综合征患者代谢综合征的患病特点

目的探索青春期多囊卵巢综合征（PCOS）患者代谢综合征（MS）患病特点。方法收集80例青春期PCOS患者MS患病率与肥胖、年龄、胰岛素抵抗和ApoB/ApoA1比值的关系。结果青春期PCOS患者MS患病率为12.50%，其中非肥胖患者MS和前代谢综合征阶段（pre-MS）患病率分别为0.00%和7.55%，低于肥胖患者的37.04%和33.33%；两组pre-MS患病率差异有统计学意义（P＜0.05）。13~15岁组MS患病率为6.67%，低于16~19岁组的13.85%（P＜0.05）；pre-MS患病率为20.00%，高于16~19岁组的15.38%。胰岛素抵抗型患者的MS和pre-MS患病率分别为33.33%和33.33%，高于非胰岛素抵抗型患者的6.45%和11.29%（P＜0.05），ApoB/ApoA1≥0.6的患者MS和pre-MS患病率分别为33.33%和16.67%，高于ApoB/ApoA1＜0.6的患者6.45%和16.13%（P＜0.05）。结论青春期PCOS患者的MS患病率以肥胖、胰岛素抵抗型、ApoB/ApoA1≥0.6者较高，其中13~15岁人群pre-MS患病率较高。     

Effects of Magnolia officinalis compatibility with Polygala tenuifolia on mitochondrial metabolism in rats’ liver based on bio-thermodynamics

Polygala tenuifolia (Yuanzhi in Chinese) has gastrointestinal toxicity which can be significantly alleviated by Magnolia officinalis (Houpo in Chinese) due to the heat production of mitochondria based on our previous study. In this paper, we have compared the different effects of M. officinalis, P. tenuifolia and their compatibility group on the mitochondrial metabolism in rats liver based on bio-thermodynamics. According to the growth thermogenic curves, we could obtain the exponential growth parameters to reflect the effect of reduced toxicity affected by M. officinalis. We also compared the further functional characteristics of M. officinalis, P. tenuifolia and their compatibility by means of statistical methods. The different experiment concentrations on mitochondrial metabolism were analyzed by principle component analysis (PCA). By analyzing the effect of different experiment concentrations on mitochondrial growth rate, we found that the metabolism rate K of mitochondria in P. tenuifolia group reduced in doses dependently. We obtained the exponential growth constant K and depicted the metabolism thermal power-time curve information of mitochondria at the same time. Our results showed that with the increased concentration of P. tenuifolia extracts, there was significant promotion of heat production by mitochondria while inhibition of M. officinalis extracts and their compatibility extracts. Analyzed by PCA, M. officinalis group distributed more scattered and had far influence on mitochondrial metabolism when compared to M. officinalis group and their compatibility group. It showed that P. tenuifolia’s gastrointestinal side effect was related to the change of mitochondrial energy metabolism.

     

冷原子吸收法测定土壤中总汞

本文使用自制的汞原子化装置，与原子吸收仪联用，采用冷原子吸收法测定土壤中总汞，该法快速，简便，稳定性好，用于实际样品测试，结果令人满意。     

推荐一个与生命科学有关的综合化学实验——牛奶中酪蛋白和乳糖的分离与鉴定

通过调节牛奶的pH分离出酪蛋白和乳糖,并采用醋酸纤维薄膜电泳、颜色反应、TLC和旋光性测定等方法鉴定酪蛋白和乳糖。使学生掌握分离纯化生物大分子物质的一些方法和手段,为参加生命科学研究打下基础。     

大气中痕量气体污染物的傅里叶变换红外光谱分析

本文从两种类型的长光程气体红外吸收方法的角度，介绍了傅里叶变换红外光谱在大气痕量气体污染物分析中的应用，并评述了它的现状和发展前景。     

石墨炉原子吸收法测定聚苯乙烯泡沫塑料中的汞

本文提出的在聚苯乙烯泡沫塑料中测定汞的方法是将样品溶解在苯中，以Ｎａ２Ｓ２Ｏ３溶液反洗出汞，利用反洗液中Ｎａ２Ｓ２Ｏ３作基体改进剂，石墨炉原子吸收法测定汞，方法简便，快速，特征量为８０ｐｇ／０．００４４Ａ。本法分析样品与冷原子荧光法的结果一致，相对标准偏差≤８％，回收率９２％－１０２％。     

壳聚糖修饰石墨电极半微分伏安法测定L-抗坏血酸

采用滴涂法制备了壳聚糖修饰石墨圆盘电极,并用于Ｌ－抗坏血酸（ＬＡＡ）的半微分伏安法测定。研究了电解液种类及酸度、膜厚度、富集电位及时间、扫速和温度等因素对伏安曲线的影响,获得了较为优化的测试条件。在０．２０ｍｏｌ／Ｌ　ＮａＨ２ＰＯ４－Ｎａ２ＨＰＯ４（ｐＨ６．０）缓冲液中,ＬＡＡ的浓度在 １． ０×１０－５～ ６． ０ × １０－４ ｍｏｌ／Ｌ范围内与氧化峰电流呈良好线性关系（ ｒ＝０．９９９７）,检测限达６．７×１０－７ｍｏｌ／Ｌ;生物体内常见的干扰物质如亚硝酸盐、多巴胺、葡萄糖等不干扰测定。 ９次测得电极在含 ５．０ ×１０－５ ｍｏｌ／Ｌ ＬＡＡ试液中峰电流的 ＲＳＤ为３．６％,回收率为９６．４％～１０２．８％（ ｎ＝５）。已成功用于维生素Ｃ片剂和人血清中 ＬＡＡ的测定。     

减阻工况下壁面周期扰动对湍流边界层多尺度的影响

通过在平板壁面施加不同频率振幅的压电陶瓷振子周期性扰动,进行了湍流边界层主动控制减阻的实验研究.在压电陶瓷振子最大减阻工况下(80 V和160Hz),使用单丝边界层探针对压电振子自由端下游2mm处进行测量,得到不同法向位置流向速度信号的时间序列.通过对比施加控制前后的多尺度分析,发现压电振子产生的扰动只对近壁区产生影响,使得近壁区大尺度脉动降低,小尺度脉动强度增大,而对边界层的外区则基本没有影响.进一步对大尺度和小尺度的脉动信号进行条件平均,发现压电振子产生的扰动对小尺度脉动的影响在时间相位上并不均匀,小尺度脉动强度在大尺度脉动为正时比在大尺度脉动为负时具有更明显的增加.这表明壁面周期扰动主要通过使大尺度高速扫掠流体破碎为小尺度结构,来影响相应的高壁面摩擦事件,从而达到减阻效果.      

Symmetries and fuzzy symmetries of Carbon nanotubes

Carbon nanotubes (CNTs) possess the fuzzy cylinder group characteristic. Comparing with the linear and planer molecules, there are included the fuzzy symmetry of the cylinder screw rotation (CSR) in relation to some higher ( $>$ 2) fold rotation axis. The CSR may be noted as the product of translation (T) and rotation (C). The CSR symmetry will be imperfect owing to the introduction of T. As the extent of whole translation is more than 10-fold than every time, the membership function of CNT in relation to CSR will be more than about 0.9, and such CNT may be seems as provided with the perfect CSR symmetry. For analyse the CNT we may using the cylindrical orthogonal curvilinear coordinate system. The MO ought to be provided with a pure irreducible representation, but the component of symmetry adapted atomic orbital (SA-AO) set may be not sole, and it is difficult to get and analyse the ‘pure’ $\uppi $ -MO. There are some various AO (1S-, 2S-, 2Pz-, 2Pr-, 2Pt of carbon and 1S- for hydrogen)-set components in a certain MO. For the CNT with the same diameter and different length, the MO energy and the SA-AO component versus the relative serial number will be with the similar distribution. The MOs of CNT with higher fold C symmetry may be provided with two-dimensional irreducible representation. For the molecular skeleton and the MO which belong to one-dimensional irreduable representation, their membership functions in relation to the CSR with the product of the same T and different C would be equality. However, for the single MO which belong to two-dimensional irreducible representation that may be somewhat difference. The torus carbon nanotube (TCNT) may be provided the symmetry with the torus group and torus screw rotation (TSR), such symmetry would be or near be not rare in nature. Similar as the planer rectangle (called as the MH rectangle) may composed the Hückel- or Möbius-strip band, the more MH rectangles in the cylinder CNT may be composed the more Hückel- or Möbius-strip bands, such strip bands set may be called strip tube, meanwhile the fuzzy CSR symmetry will be transform to the perfect TSR symmetry. The intersecting line (Z-axis) of the MH rectangles will be transform to the common basic circle of these strip bands. When the CNT to form a TCNT, as one of the MH rectangle form a Hückel-strip band or an $n(t)$ -twisted Möbius-strip band itself, the other MH rectangle will be form the strip band with the same topological structure synchronously, and the set of these strip bands may be called the strip tube. The boundary closed curves of the strip band may reflect the torus group symmetrical characteristic of the relative strip bands. The closed curve may correspond to a cyclical group or subgroup. The number of carbon atomic pairs on the closed curve denoted the order of such group or subgroup. As the CNT to form the TCNT, it is different as the single MH rectangle, they may be to form the fractal-twisted Möbius-strip tube synchronously, in which the single Möbius-strip band may be formed from more one MH rectangle, however, single MH rectangle may enter into only one Möbius-strip band. As the hetero-CNT with the helical-structure distribution, such hetero-CNT may form the relative torus hetero-CNT, but according to the continuity of CNT tube side, a certain twisted to form Möbius-strip tube may often be required. There is some interaction between the distributional helical-structure and twisting way, such interaction may touch to the degree of tightness of the helical-structure distribution in torus hetero-CNT.