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171.
Development of x-ray scintillator functioning also as an analyser grating used in grating-based x-ray differential phase contrast imaging 下载免费PDF全文
In order to push the grating-based phase contrast imaging system to be used in hospital and laboratories,this paper designs and develops a novel structure of x-ray scintillator functioning also as an analyser grating,which has been proposed for grating-based x-ray differential phase contrast imaging. According to this design,the scintillator should have a periodical structure in one dimension with the pitch equaling the period of self-image of the phase grating at the Talbot distance,where one half of the pitch is pixellated and is made of x-ray sensitive fluorescent material,such as CsI(Tl),and the remaining part of the pitch is made of x-ray insensitive material,such as silicon. To realize the design,a deep pore array with a high aspect ratio and specially designed grating pattern are successfully manufactured on 5 inch silicon wafer by the photo-assisted electrochemical etching method. The related other problems,such as oxidation-caused geometrical distortion,the filling of CsI(Tl) into deep pores and the removal of inside bubbles,have been overcome. Its pixel size,depth and grating pitch are 3 μm×7.5 μm,150 μm and 3 μm,respectively. The microstructure of the scintillator has been examined microscopically and macroscopically by scanning electron microscope and x-ray resolution chart testing,respectively. The preliminary measurements have shown that the proposed scintillator,also functioning as an analyser grating,has been successfully designed and developed. 相似文献
172.
大鼠神经介素B受体(rat neuromedin B receptor, rNMBR)属于G蛋白偶联受体(G-protein coupled receptor, GPCR) A家族的成员. GPCR的结构特征和在信号传导中的重要作用决定了其可以作为很好的药物靶标. 关于rNMBR与内源性激动剂神经介素B (neuromedin B, NMB)以及与非肽类拮抗剂pd168368作用机制的研究对于合理设计受体药物分子有重要的指导意义. 在这一研究中, 我们使用同源模建, 构建受体的三维结构, 进行分子对接和分子动力学的计算. 基于受体三维结构, 通过10 ns的空载受体、激动剂-受体、拮抗剂-受体的分子动力学模拟, 探讨受体与激动剂与拮抗剂的作用机制. 研究表明rNMB-R中跨膜(transmembrane, TM)螺旋3, 5, 6, 7参与配体的结合. NMB与受体的结合, 使受体转变为活性构象, 而受体同拮抗剂pd168368恰好相反. 相似文献
173.
This paper gives theoretical analysis of visibility of fringes,
which is influenced by distances, temporal and spatial coherence
of source, in hard x-ray differential phase-contrast imaging
with microfocus x-ray source. According to the character of
longitudinal periodicity of the interferogram, the setup is
insensitive to mechanical drift and vibrations. The effect of
temporal coherence of x-ray source is investigated and its
related bandwidth is derived. Based on the theory of partially
coherent light, it shows that the requirement for the spatial
coherence of x-ray source is not strict and can be met by the
general microfocus x-ray tube for x-ray differential
phase-contrast imaging. 相似文献
174.
二维相关光谱技术(2D-COS)、三维荧光光谱技术结合平行因子分析(EEM-PARAFAC)具有扩展识别重叠峰,判断不同组分动态变化规律的技术特点。因此,2D-COS和EEM-PARAFAC分析技术可以用来分析溶解性有机质(DOM)结构组成和光谱变化特征。采用溶解性有机碳(DOC)、紫外-可见吸收光谱(UV)和EEM分析技术,借助2D-COS和PARAFAC分析模型,对青藏高原具有代表性的察尔汗盐湖、西台吉乃尔盐湖和马海盐湖中DOM在盐田摊晒过程中的结构组成和光谱学变化特征进行了研究。结果表明,随着日照时间延长,盐田中DOM和有色DOM(CDOM)含量逐渐升高,且DOM的增长倍数明显高于CDOM。在整个盐田摊晒阶段,察尔汗、西台吉乃尔和马海盐田中DOM和CDOM分别增长了1.5 vs. 1.0、 8.2 vs. 5.3和15.7 vs. 11.0倍。此外,SUVA254、 HIX值在盐田中总体上呈现出逐渐减小的变化趋势。2D UV-COS分析结果表明,在察尔汗、西台吉乃尔和马海盐田中,吸收峰分别在230、 217和235 nm处的DOM变动较大,变化顺序分别为22... 相似文献
175.
采用316L不锈钢材质的锐角圆锥块作为摩擦对偶,在硼酸锂的液流条件下对2种Zr(-Sn)-Nb合金管进行不同循环次数(N=102,103,104,105,106)的冲击试验.模拟了锆合金包壳在异物磨蚀情况下的冲击状态,研究了2种Zr(-Sn)-Nb合金管的冲击磨损性能及冲击磨损机制.结果表明,锆合金管材在冲击磨损作用下的磨损机制主要为塑性变形和疲劳剥落.机械性能、动力学曲线和冲击磨损试验等数据皆表明,Zr-Sn-Nb合金拥有比Zr-Nb合金更好的抵抗316L不锈钢冲击磨损的能力.磨痕边缘材料塑性流动导致的裂纹形成与扩展及磨痕底部裂纹延伸交汇后发生的疲劳剥落,都会对锆合金管造成严重的磨损去除.冲击过程中,锆合金管与摩擦对偶会发生材料迁移,形成Zr、O、C、Fe元素不均匀分布的磨屑堆积层. 相似文献
176.
为提高大过载高动态环境下捷联惯导系统导航精度,需对捷联惯导系统中的石英挠性加速度计非线性误差参数进行精确标定。针对现有标定方法在加速度计非线性误差参数发生变化时无法满足免拆卸高精度标定的问题,设计了一种基于双轴精密离心机和捷联惯导系统转位机构交替旋转、依靠转位机构实现9位置标定路径的系统级标定方法。经理论分析和仿真验证,所提方法可实现加速度计二次项、交叉耦合项共九个非线性误差参数系统级高精度标定,二次项误差参数标定精度优于1.0×10-6 g/g2,交叉耦合项误差参数标定精度优于1.5×10-6 g/g2。 相似文献