Nonlinear finite element analysis of inflatable beams made from orthotropic woven fabric

This paper was devoted to the three-dimensional nonlinear finite element analysis of inflatable beams. The beams under consideration are made of modern textile materials and can be used as a load-bearing beams or arches when inflated. A 3D Timoshenko beam with a homogeneous orthotropic woven fabric (OWF) was proposed. The model took into account the geometric nonlinearities and the follower force resulting from the inflation pressure. The use was made of the usual total Lagrangian form of the virtual work principle to perform the nonlinear equilibrium equations which were discretized by the finite element method. Two kinds of solutions were then investigated: finite elements solutions for linearized problems which were obtained by the means of the linearization around the prestressed reference configuration of the nonlinear equations and nonlinear finite element solutions which were performed by the use of an optimization algorithm based on the Quasi-Newton method. As an example, the bending problem of a cantilever inflated beam under concentrated load was considered and the deflection results improve the existing theoretical models. As these beams are made from fabric, the beam models were validated through their comparison with a 3D thin-shell finite element model. The influence of the material effective properties and the inflation pressure on the beam response was also investigated through a parametric study. The finite elements solutions for linearized problems were found to be close to the theoretical results existing in the literature. On the other hand, the results for the nonlinear finite element model were shown to be close to the results for the linearized finite elements model in the case of high mechanical properties and the nonlinear finite element model was used to improve the linearized model when the mechanical properties of the fabric are low.     

Lesson study in a blended approach to support isolated teachers in teaching with technology

Lesson study (LS) is a form of professional development, with a strong foundation in mathematics education, based on teachers collaborating to design lesso     

The quality-management system in research implemented in the food and food process quality research laboratory of the French Food Safety Agency

The French Food Safety Agency is a public body incorporating 12 laboratories that perform research to support expertise and public decisions taken in the fields of sanitary safety of food, animal health, and veterinary drugs. On the request of the General Management of the Agency a quality-management system in research (QMSR) is being implemented in the Food and Food Process Quality Research Laboratory. The experimental QMSR is based on existing standards and documents, describing the provisions required for scientific and technical competence, quality management, and project management. Furthermore, this QMSR also incorporates specific notions of great importance for research activities such as the positive and negative non-conformities, the non-confirmation of hypotheses, and the principle of evaluation of a research activity by peers for both quality and scientific aspects.

     

Collaborative study for the detection of toxic compounds in shellfish extracts using cell-based assays. Part II: application to shellfish extracts spiked with lipophilic marine toxins

Successive unexplained shellfish toxicity events have been observed in Arcachon Bay (Atlantic coast, France) since 2005. The positive mouse bioassay (MBA) revealing atypical toxicity did not match the phytoplankton observations or the liquid chromatography-tandem mass spectrometry (LC-MS/MS) investigations used to detect some known lipophilic toxins in shellfish. The use of the three cell lines (Caco2, HepG2, and Neuro2a) allows detection of azaspiracid-1 (AZA1), okadaic acid (OA), or pectenotoxin-2 (PTX2). In this study, we proposed the cell-based assays (CBA) as complementary tools for collecting toxicity data about atypical positive MBA shellfish extracts and tracking their chromatographic fractionation in order to identify toxic compound(s). The present study was intended to investigate the responses of these cell lines to shellfish extracts, which were either control or spiked with AZA1, OA, or PTX2 used as positive controls. Digestive glands of control shellfish were extracted using the procedure of the standard MBA for lipophilic toxins and then tested for their cytotoxic effects in CBA. The same screening strategy previously used with pure lipophilic toxins was conducted for determining the intra- and inter-laboratory variabilities of the responses. Cytotoxicity was induced by control shellfish extracts whatever the cell line used and regardless of the geographical origin of the extracts. Even though the control shellfish extracts demonstrated some toxic effects on the selected cell lines, the extracts spiked with the selected lipophilic toxins were significantly more toxic than the control ones. This study is a crucial step for supporting that cell-based assays can contribute to the detection of the toxic compound(s) responsible for the atypical toxicity observed in Arcachon Bay, and which could also occur at other coastal areas.