An integral representation for decomposable measures of measurable functions

Summary We start with a measurem on a measurable space (,A), decomposable with respect to an Archimedeant-conorm on a real interval [0,M], which generalizes an additive measure. Using the integral introduced by the second author, a Radon-Nikodym type theorem, needed in what follows, is given.The integral naturally leads to a -decomposable measurem on the space of all measurable functions from to [0, 1]. The main result of the present paper is the converse of this, namely that, under natural conditions, any -decomposable measurem on can be represented as an integral of a certain Markov-kernelK. We extend this representation to measures on which have values in a set of distribution functions.These results generalize the work done by the first author in the case of additive measures.     

Algebras of sets generating non-barrelled spaces

IfA is a -algebra on setX, thenl ₀ (X,A) is a barrelled space of class ₀. IfA is an algebra, there are conditions which imply thatl ₀ (X,A) is suprabarelled. Here, wheneverA is an algebra, we give conditions forl ₀ (X,A) to be not barrelled which are related with the existence of non-trivial convergent sequences.Supported in part by DGICYT, project PB91-0407 and by the Institució Valenciana d'Estudis i Investigació, project 023.     

Dimension and entropy of a non-ergodic Markovian process and its relation to Rademacher Riesz Products

Given a Markov chain (not necessarily stationary or homogeneous) with finite state space and an initial distribution, we can construct a measure on the unit interval [0, 1]. In this work we examine the equality (up to a constant) of the Hausdorff dimension of and of a suitably defined entropy for the Markovian process. The results are applied to the so-called Rademacher-Riesz Products.     

Nonlinear transformations of the canonical gauss measure on Hilbert space and absolute continuity

The papers of R. Ramer and S. Kusuoka investigate conditions under which the probability measure induced by a nonlinear transformation on abstract Wiener space(,H,B) is absolutely continuous with respect to the abstract Wiener measure. These conditions reveal the importance of the underlying Hilbert spaceH but involve the spaceB in an essential way. The present paper gives conditions solely based onH and takes as its starting point, a nonlinear transformationT=I+F onH. New sufficient conditions for absolute continuity are given which do not seem easily comparable with those of Kusuoka or Ramer but are more general than those of Buckdahn and Enchev. The Ramer-Itô integral occurring in the expression for the Radon-Nikodym derivative is studied in some detail and, in the general context of white noise theory it is shown to be an anticipative stochastic integral which, under a stronger condition on the weak Gateaux derivative of F is directly related to the Ogawa integral.Research supported by the National Science Foundation and the Air Force Office of Scientific Research Grant No. F49620 92 J 0154 and the Army Research Office Grant No. DAAL 03 92 G 0008.     

On measurable multifunctions in countably separated spaces

We use an idea of countable separability of points and sets in topological spaces to prove results on intersection of measurable multifunctions and an implicit function theorem. We generalize or extend in part some well known Himmelberg's theorems.     

Harmonic analysis in infinite dimension

We study the Hermite transform onL ²() where is a Gaussian measure on a Lusin locally convex spaceE. We are then lead to a Hilbert space () of analytic functions onE which is also a natural range for the Laplace transform. LetB be a convenient Hilbert-Schmidt operator on the Cameron-Martin spaceH of . There exists a natural sequence Cap _n of capacities onE associated toB. This implies the Kondratev-Yokoi theorem about positive linear forms on the Hida test-functions space.     

The quality of the Diophantine approximations found by the Jacobi-Perron algorithm and related algorithms

Given a vector of real numbers=(₁,... _d ) ^d , the Jacobi-Perron algorithm and related algorithms, such as Brun's algorithm and Selmer's algorithm, produce a sequence of (d+1)×(d+1) convergent matrices {C⁽ⁿ⁾():n1} whose rows provide Diophantine approximations to . Such algorithms are specified by two mapsT:[0, 1] ^d [0, 1] ^d and A:[0,1] ^d GL(d+1,), which compute convergent matrices C⁽ⁿ⁾())...A(T())A(). The quality of the Diophantine approximations these algorithms find can be measured in two ways. The best approximation exponent is the upper bound of those values of for which there is some row of the convergent matrices such that for infinitely many values ofn that row of C⁽ⁿ⁾() has . The uniform approximation exponent is the upper bound of those values of such that for all sufficiently large values ofn and all rows of C⁽ⁿ⁾⁽⁾ one has . The paper applies Oseledec's multiplicative ergodic theorem to show that for a large class of such algorithms and take constant values and on a set of Lebesgue measure one. It establishes the formula where are the two largest Lyapunov exponents attached by Oseledec's multiplicative ergodic theorem to the skew-product (T, A,d), whered is aT-invariant measure, absolutely continuous with respect to Lebesgue measure. We conjecture that holds for a large class of such algorithms. These results apply to thed-dimensional Jacobi-Perron algorithm and Selmer's algorithm. We show that; experimental evidence of Baldwin (1992) indicates (nonrigorously) that. We conjecture that holds for alld2.     

An application of Shoenfield's absoluteness theorem to the theory of uniform distribution

IfC is a Polish probability space, a Borel set whose sectionsW _x ( have measure one and are decreasing , then we show that the set _x W _x has measure one. We give two proofs of this theorem—one in the language of set theory, the other in the language of probability theory, and we apply the theorem to a question on completely uniformly distributed sequences.Supported by DFG grant Ko 490/7-1.     

Contribution of cyclodextrins in the development of different pharmaceutical formulations of a new matrix metalloproteinase inhibitor

Ro 28-2653 is a new synthetic inhibitor of matrix metalloproteinases. The ability of these enzymes to degrade various components of the extracellular matrix seems to play a major role in tumors progression and is potentially effective against bronchial remodeling in asthma and BPCO. Ro 28-2653 is very poorly soluble in water. This low solubility estimated at about 0.56 μg/ml in water at 25 °C gives rise to difficulties in pharmaceutical formulation of oral, injectable or nebulizable solutions. The purpose of our study is to prepare and to characterize inclusion complexes between Ro 28-2653 and cyclodextrins and to investigate the biopharmaceutical repercussion of the inclusion of the active substance. The complex formation was investigated by phase solubility studies. ¹H-NMR spectroscopy and molecular modeling studies were carried out to elucidate the structure of the inclusion complex between Ro 28-2653 and cyclodextrin. Oral, intravenous and nebulizable solutions of Ro 28-2653 were developed with cyclodextrin. The in vivo studies were performed on healthy sheep for the pharmacokinetic evaluation of the oral and intravenous formulations while the nebulization of the complex solution was studied by using an asthma model in mouse.     

C28X4（X=H,Cl）,CX4（X=H,Cl）的结构和电子光谱的理论研究

用ＩＮＤＯ法对Ｃ２８Ｘ４（Ｘ＝Ｈ，Ｃｌ）和ＣＸ４（Ｘ＝Ｈ，Ｃｌ）进行几何构型优化，得到Ｔｄ对称性的构型Ｃ２８Ｘ４有４种键、４种不等同原子，基态为稳定的闭壳层分子，以此构型为基础计算了上述分子的电子光谱，并预测Ｃ２８Ｘ４的电子光谱。