聚二乙烯苯整体柱的制备及其在气相色谱分析中的应用

初步探讨了毛细管整体柱的制备方法及其在气相色谱分析中的应用。以液相色谱用毛细管整体柱作为研究基础,通过改变甲苯和十二醇的比例,使整体柱适用于气相色谱分析。通过二乙烯苯与键合在管壁上的3-(异丁烯酰氯)丙基三甲氧基硅烷(TMP)键合以及其自身的聚合,获得具有牢固结构、良好机械强度的整体柱。将其用于混合溶剂的分析和白酒标样的分析,可直接分析水中低碳醇。与现有的商品柱进行比较,结果表明所制备的整体柱均优于用以对照的商品色谱柱,其中在混合溶剂的分析中,醇类、酯类、酮类和芳烃类的峰形均优于用于比较的多孔层开口管(PLOT)柱;在白酒标样分析中,使得乙醛、甲醇、乙酸乙酯的色谱峰能够分开,比现有的聚乙二醇(PEG-20M)柱的分析方法更为便捷。     

A facile approach to fabricate and embed multifunctional nano ZnO into soap matrix and liquid cleansing products for enhanced antibacterial and photostability for health and hygiene applications

This research demonstrates, a facile approach to fabricate the nano ZnO system in an unique combination of surfactant-polyol-assembly (SPA) acting as a caging agent restricting the ZnO crystallite size in nano-regime. This SPA is suitable for health and hygiene products and such optimized technique is among the very few researches exploring the impact of embedding low concentrations of nano ZnO system into the matrix of sodium salt of long chain fatty acids (soap bar) and liquid cleansing personal care products. The fabricated nano ZnO in SPA and infused products were systematically characterized using various advanced and appropriate techniques. The hexagonal wurtzite structure of nano ZnO-SPA is evaluated based on XRD pattern which also exhibit an average crystallite size as 20.18 nm and high specific surface area as 52.99 m²/g. The SEM-supported morphological assessment confirms the formation of agglomerates of ultrafine ZnO rods and spherical particles. Novel nano ZnO having wideband gap energy (3.66 eV) embedded in soap bar act as a UV-blocker preventing the oxidation of unsaturated long chain fatty acids. Soap bar without ZnO experienced degradation and reduction in whiteness to 17.85% whereas 2.5 mg/g nano ZnO infused soap shows the reduction to 7.9% which clearly reflects the increased photostability of soap bar. The antibacterial efficacy of nano ZnO-SPA and infused products are investigated against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) by Zone of Inhibition (ZOI) and European standard EN:1276. Infused products exhibited high antibacterial efficacy up to 4.43 log reduction equivalent to >99.99% germ kill.     

激光光源线宽对外差探测性能的影响

本文根据统计理论分析了激光线宽对外差探测结果的影响, 并讨论了激光线宽对杨氏干涉条纹对比度的影响. 本文基于解析结果做了数值仿真, 所得结果表明激光线宽增加时, 外差探测方式仍可以检测到中频信号, 但在线宽较大时, 受噪声影响无法准确地提取到中频频率. 为验证理论分析结果, 使用线宽为1 MHz的激光光源进行了8.1 km外场实验, 实验结果与数值分析结论一致, 即不会因为线宽增加而无法检测到中频信号. 文中所得结论对于外差探测光源的选择有重要指导意义, 因此根据测量目标的特性和测量要求, 可按照文中结论评估光源的线宽指标.     

Magnetic fields associated with a nuclear magnetic resonance medical imaging system

Measurements were made of magnetic and electric field levels in and around a nuclear magnetic resonance imaging system undergoing a clinical trial. Magnetic field levels ranged from 0.04 tesla (T) in the imaging volume down to about 0.0006 T at the end of the patient table. The peak radio-frequency magnetic field level was 15 amperes per meter (A/m) in the imaging volume, while the rms value was 4.6 A/m. The specific absorption rate resulting from the radio-frequency magnetic field was calculated to be no more than 0.017 watts per kilogram (W/kg). The radio-frequency electric field was detectable only within a few centimeters of the coil assembly, and does not significantly contribute to the specific absorption rate. These exposure levels were much lower than existing guidelines for clinical NMR procedures.     

Microfluidic-based nanoparticle synthesis and their potential applications

A lot of substantial innovation in advancement of microfluidic field in recent years to produce nanoparticle reveals a number of distinctive characteristics, for instance, compactness, controllability, fineness in process, and stability along with minimal reaction amount. Recently, a prompt development, as well as realization in the production of nanoparticles in microfluidic environment having dimension of micro to nanometers and constituents extending from metals, semiconductors to polymers, has been made. Microfluidics technology integrates fluid mechanics for the production of nanoparticles having exclusive with homogenous sizes, shapes, and morphology, which are utilized in several bioapplications such as biosciences, drug delivery, and healthcare including food engineering. Nanoparticles are usually well-known for having fine and rough morphology because of their small dimensions including exceptional physical, biological, chemical, and optical properties. Though the orthodox procedures need huge instruments, costly autoclaves, use extra power, extraordinary heat loss, as well as take surplus time for synthesis. Additionally, this is fascinating to systematize, assimilate, in addition, to reduce traditional tools onto one platform to produce micro and nanoparticles. The synthesis of nanoparticles by microfluidics permits fast handling besides better efficacy of method utilizing the smallest components for process. Herein, we will focus on synthesis of nanoparticles by means of microfluidic devices intended for different bioapplications.     

Dye attached poly(hydroxyethyl methacrylate) cryogel for albumin depletion from human serum

Cibacron Blue F3GA was immobilized on poly(hydroxyethyl methacrylate) cryogel and it was used for selective and efficient depletion of albumin from human serum. The poly(hydroxyethyl methacrylate) was selected as the basic component because of its inertness, mechanical strength, chemical and biological stability, and biocompatibility. Cibacron Blue F3GA was covalently attached to the poly(hydroxyethyl methacrylate) cryogel to produce poly(hydroxyethyl methacrylate)-Cibacron Blue F3GA cryogel affinity column. The poly(hydroxyethyl methacrylate)-Cibacron Blue F3GA cryogel was characterized with respect to gelation yield, swelling degree, total volume of macropores, Fourier Transform Infrared spectroscopy, and scanning electron microscopy. It was found that the maximum amount of adsorption (343 mg/g of dry cryogel) obtained from experimental results is very close to the calculated Langmuir adsorption capacity (345 mg/g of dry cryogel). The maximum adsorption capacity for poly(hydroxyethyl methacrylate)-Cibacron Blue F3GA cryogel column was obtained as 950 mg/g of dry cryogel for nondiluted serum. The adsorption capacity decreased with increasing dilution ratios while the depletion ratio of albumin remained as 77% in serum sample. Finally, the poly(hydroxyethyl methacrylate)-Cibacron Blue F3GA cryogel was optimized for using in the fast protein liquid chromatography system for rapid removal of the high abundant proteins from the human serum.     

Hexagonal boron nitride quantum dots: Properties,preparation and applications

As a new type of quantum dots (QDs), hexagonal boron nitride quantum dots (BNQDs) exhibit promising potential in the applications of disease diagnosis, fluorescence imaging, biosensing, metal ion detection, and so on, because of their remarkable chemical stability, excellent biocompatibility, low cytotoxicity, and outstanding photoluminescence properties. However, the large-scale fabrication of homogeneous BNQDs still remains challenging. In this article, the properties and common fabrication methods of BNQDs are summarized based on the recent research progress. Then, the corresponding yields, morphologies, and fabrication mechanisms of these as-obtained BNQDs are discussed in detail. Moreover, the applications of these as-obtained BNQDs in different fields are also discussed. This article is expected to inspire new methods and improvements to achieve large-scale fabrication of homogeneous BNQDs, which will enable their practical applications in future.     

GC-MS with ethyl chloroformate derivatization for comprehensive analysis of metabolites in serum and its application to human uremia

An optimized method based on GC-MS with ethyl chloroformate derivatization has been developed for the comprehensive analysis of endogenous metabolites in serum. Twenty-two reference standards and serum samples were used to validate the proposed method. The correlation coefficient was higher than 0.9900 for each of the standards, and the LOD varied from 125 to 300 pg on-column. The analytical equipment exhibited good repeatability (RSD<10%) for all of the standards. Both the repeatability and the within-48-h stability of the analytical method were satisfactory (RSD<10%) for the 18 metabolites identified in the serum samples. Mean recovery was acceptable for the 18 metabolites, ranging from 70% to 120% with RSDs of less than 10%. Using the optimized protocol and a subsequent multivariate statistical technique, complete differentiation was achieved between the metabolic profile of uremic patients and that of age- and sex-matched normal subjects. Significantly decreased levels of valine, leucine, and isoleucine and increased levels of myristic acid and linoleic acid were observed in the patient group. This work demonstrated that this method is suitable for serum-based metabolic profiling studies.     

Recent advances in the synthesis,biological activities and various applications of ferrocene derivatives

Ferrocene derivatives constitute an important class of organometallic compounds with not only an extensive range of biological activities but also diverse industrial as well as material science applications. These stimulating features of ferrocene derivatives spurred us to review the recent advances in synthesis methods and biological and other applications reported in the latest literature. An effort has been made to summarize the recent developments in synthetic methods providing access to ferrocene scaffolds and the useful medicinal and material applications, including agricultural, catalytic, polymer, conducting, redox mediating, ferrocenyl stationary phase, rocket propellant and ion sensing applications. Ferrocene‐based bulky metallocenes are also discussed.     

Parallel computation of turbulent flows using moment base lattice Boltzmann method

This paper describes parallel computing approach for simulating turbulent flows using a moment base lattice Boltzmann method. The distribution functions of the lattice Boltzmann method are expressed by corresponding moments. Choosing proper relaxation times for higher order moments, a minimum numerical dissipation is implicitly added to stabilise the method at high Reynolds numbers. Validation of the method is made by computing free decaying periodic turbulent flows and fully developed turbulent channel flows on a GPU platform. Though the present method requires additional work to calculate the higher order moments, it is shown that additional computational cost is negligible in the GPU computing. The numerical results stably obtained for the turbulent flows are in good agreement with those of a pseudo-spectral method and corresponding DNS database.