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991.
It is proved in this paper that an RGD(3, g;v) can be embedded in an RGD(3, g;u) if and only if
,
,
, v ≥ 3g, u ≥ 3v, and (g,v) ≠ (2,6),(2,12),(6,18). 相似文献
992.
Peter Danziger Peter Dukes Terry Griggs Eric Mendelsohn 《Graphs and Combinatorics》2006,22(3):311-329
A Steiner triple system of order v, or STS(v), is a pair (V, ) with V a set of v points and a set of 3-subsets of V called blocks or triples, such that every pair of distinct elements of V occurs in exactly one triple. The intersection problem for STS is to determine the possible numbers of blocks common to two Steiner triple systems STS(u), (U, ), and STS(v), (V, ), with U⊆V. The case where U=V was solved by Lindner and Rosa in 1975. Here, we let U⊂V and completely solve this question for v−u=2,4 and for v≥2u−3.
supported by NSERC research grant #OGP0170220.
supported by NSERC postdoctoral fellowship.
supported by NSERC research grant #OGP007621. 相似文献
993.
Mike J. Grannell Terry S. Griggs Anne Penfold Street 《Designs, Codes and Cryptography》2006,40(2):225-236
It is shown that in some cases it is possible to reconstruct a block design
uniquely from incomplete knowledge of a minimal defining set for
. This surprising result has implications for the use of minimal defining sets in secret sharing schemes. 相似文献
994.
995.
996.
A transportable GC x GC instrument is under development for on-site applications that would benefit from the enhanced resolution and powers of detection, which can be achieved by this method. In the present study, a low-resource GC x GC instrument using an electrically heated and liquid-cooled single-stage thermal modulator that requires no cryogenic materials is evaluated. The instrument also uses at-column heating, thus eliminating the need for a convection oven to house the two columns. The stainless-steel modulator tube is coated with PDMS, which can be heated to 350 degrees C for sample injection into the second-dimension column. The modulator is cooled to -30 degrees C by a 100 mL/min flow of PEG by means of a commercial liquid chiller and a small recirculating pump. Resistive heating of the modulator tube is provided by a programmable power supply, which uses a voltage program that results in increasing modulator temperature during an analysis. This, together with more rapid cooling by the use of a liquid cooling medium, results in reduced solute breakthrough following each heating cycle as the modulator cools to a temperature where quantitative trapping resumes. As a result, modulated peak widths at half-height of less than 40 ms are observed. Design and performance details are presented along with chromatograms of gasoline and an essential oil sample. 相似文献
997.
Chemoinformatics: a new field with a long tradition 总被引:2,自引:0,他引:2
Gasteiger J 《Analytical and bioanalytical chemistry》2006,384(1):57-64
Chemoinformatics is the application of informatics methods to solve chemical problems. Although this term was introduced only
a few years ago, this field has a long history with its roots going back more than 40 years. Work on chemical structure representation
and searching, quantitative structure–activity relationships, chemometrics, molecular modeling as well as computer-assisted
structure elucidation and synthesis design was initiated in the 1960s. These different origins have now merged into a discipline
of its own that is in full bloom. All areas of chemistry from analytical chemistry to drug design can benefit from chemoinformatics
methods. And there are still many challenging chemical problems waiting for solutions through the further development of chemoinformatics. 相似文献
998.
999.
1000.
Apoptolidin is a natural product that selectively induces apoptosis in several cancer cell lines. Apoptosis, programmed cell death, is a biological key pathway for regulating homeostasis and morphogenesis. Apoptotic misregulations are connected with several diseases, in particular cancer. The extrinsic way to apoptosis leads through death ligands and death receptors to the activiation of the caspase cascade, which results in proteolytic degradation of the cell architecture. The intrinsic pathway transmits signals of internal cellular damage to the mitochondrion, which loses its structural integrity, and forms an apoptosome that initiates the caspase cascade. Compounds which regulate apoptosis are of high medical significance. Many natural products regulate apoptotic pathways, and apoptolidin is one of them. The known synthetic routes to apoptolidin are described and compared in this Review. Selected further natural products which regulate apoptosis are introduced briefly. 相似文献