共焦激光扫描荧光显微镜的扫描系统研究

简述共焦激光扫描荧光显微镜的基本原理，给出了扫描系统的方案确定和优化设计的方法，使用该方法可使扫描渐晕减少为原来的１％。同时还给出了扫描控制系统的运行和控制法以及获得均匀图像的补偿方法。     

电动车电驱动技术研究

指出了传统式电动车直流电驱动技术中的问题，提出了电动车电驱动技术的设计思路和技术方案。     

三相异步电动机一相绕组短路后另二相绕组组合运行分析

当三相异步电动机正常运行时因某种原因一相绕组烧毁,通过对剩下二相绕组重新组合的3 种方法进行分析,发现其中二相零接法在适当降低负载功率情况下,电机可连续运行.     

直线步进电机的计算机控制系统

基于作者完成的直线步进电机计算机控制系统,提出了二相混合式直线步进电机的最佳控制方案和控制函数。对直线步进电机有关机电性能的试验表明,由于采用了本文提出的最佳控制方案和控制函数,电机不但获得了高的定位分辨率,而且起动和停止时变得稳定。电机的动态特性也大大改善,在极低速运行时,也完全避免了电机机械谐振的出现。我们看到,正是由于采用了计算机控制技术,才有可能使直线步进电机特有的功能和长处得以充分发挥,并将为直线步进电机的成功应用开拓广阔前景。     

基于PXI和RT-LAB的永磁同步电机快速控制原型设计

针对永磁同步电机控制器存在算法复杂、代码量大、开发周期长等问题,实现一种基于虚拟仪器的永磁同步电机快速控制原型系统。设计快速控制原型硬件平台,并对硬件设备进行选型,包括PXI虚拟仪器、功率驱动模块、电机对拖台架等;研究永磁同步电机转子磁场定向控制原理基础上,以一台3.1KW被测电机为被控对象,在RT-LAB实时仿真软件环境下,搭建永磁同步电机控制算法模型。实验结果表明,电机转速与定子电流均可无偏差跟踪参考给定值,系统控制性能良好,且该系统使电机控制器开发周期缩短、成本降低。     

Autonomous movement of silica and glass micro-objects based on a catalytic molecular propulsion system

A general approach for the easy functionalization of bare silica and glass surfaces with a synthetic manganese catalyst is reported. Decomposition of H(2)O(2) by this dinuclear metallic center into H(2)O and O(2) induced autonomous movement of silica microparticles and glass micro-sized fibers. Although several mechanisms have been proposed to rationalise movement of particles driven by H(2)O(2) decomposition to O(2) and water (recoil from O(2) bubbles, ([36,45]) interfacial tension gradient([37-42]), it is apparent in the present system that ballistic movement is due to the growth of O(2) bubbles.     

基于巨磁电阻的转速测量在实验教学中的应用

介绍了巨磁电阻梯度传感器工作原理,设计、制作了适用于实验教学的巨磁电阻转速测量实验装置,实现了通过单片机对步进电机转速的控制及对被测转盘转速的实时测量,给出了电机工作在不同转速状态下的测量结果,验证了同步电机转速与控制频率的变化关系。     

Complexity Measures of Heart-Rate Variability in Amyotrophic Lateral Sclerosis with Alternative Pulmonary Capacities

Objective: the complexity of heart-rate variability (HRV) in amyotrophic lateral sclerosis (ALS) patients with different pulmonary capacities was evaluated. Methods: We set these according to their pulmonary capacity, and specifically forced vital capacity (FVC). We split the groups according to FVC (FVC > 50% (n = 29) and FVC < 50% (n = 28)). In ALS, the presence of an FVC below 50% is indicative of noninvasive ventilation with two pressure levels and with the absence of other respiratory symptoms. As the number of subjects per group was different, we applied the unbalanced one-way analysis of variance (uANOVA1) test after three tests of normality, and effect size by Cohen’s d to assess parameter significance. Results: with regard to chaotic global analysis, CFP4 (p < 0.001; d = 0.91), CFP5 (p = 0.0022; d = 0.85), and CFP6 (p = 0.0009; d = 0.92) were enlarged. All entropies significantly increased. Shannon (p = 0.0005; d = 0.98), Renyi (p = 0.0002; d = 1.02), Tsallis (p = 0.0004; d = 0.99), approximate (p = 0.0005; d = 0.97), and sample (p < 0.0001; d = 1.22). Detrended fluctuation analysis (DFA) (p = 0.0358) and Higuchi fractal dimension (HFD) (p = 0.15) were statistically inconsequential between the two groups. Conclusions: HRV complexity in ALS subjects with different pulmonary capacities increased via chaotic global analysis, especially CFP5 and 3 out of 5 entropies.     

JF1/B6F1 Ngly1−/− mouse as an isogenic animal model of NGLY1 deficiency

N-Glycanase 1 (NGLY1) deficiency is a congenital disorder caused by mutations in the NGLY1 gene. Because systemic Ngly1^−/− mice with a C57BL/6 (B6) background are embryonically lethal, studies on the mechanism of NGLY1 deficiency using mice have been problematic. In this study, B6-Ngly1^−/+ mice were crossed with Japanese wild mice-originated Japanese fancy mouse 1 (JF1) mice to produce viable F₂ Ngly1^−/− mice from (JF1×B6)F₁ Ngly1^−/+ mice. Systemic Ngly1^−/− mice with a JF1 mouse background were also embryonically lethal. Hybrid F1 Ngly1^−/− (JF1/B6F1) mice, however, showed developmental delay and motor dysfunction, similar to that in human patients. JF1/B6F1 Ngly1^−/− mice showed increased levels of plasma and urinary aspartylglycosamine, a potential biomarker for NGLY1 deficiency. JF1/B6F1 Ngly1^−/− mice are a useful isogenic animal model for the preclinical testing of therapeutic options and understanding the precise pathogenic mechanisms responsible for NGLY1 deficiency.     

控制力矩陀螺用高性能永磁无刷直流电机研究

无刷直流电动机作为控制力矩陀螺驱动电机，要求具有10倍的最大功率倍数，这给电机的设计带来很大难度。该提出的绕组换接运行，在满足控制力矩陀螺驱动要求的前提下，不但可以使电机最大功率倍数，从而使系统逆变器容量降低，同时可以大大降低系统的损耗，提高系统的运行效率。通过理论分析和样机试验证明了绕组换接的有效性。