Some applications of capillary gas chromatography in the chemical industry

About three years ago, fused silica capillary columns were introduced in the Quality Control Laboratory of the Shell refinery/chemical complex at Pernis. In general, long, thick-film, wide-bore capillary columns are used together with low split ratios and hydrogen as carrier gas. These conditions enable the analysis of relatively large sample amounts, resulting in low detection limits for the minor components without overloading by the major components, while still maintaining a satisfactory resolution. A number of applications are shown, such as the analysis of complex mixtures, the determination of trace impurities and the analysis of residual volatiles in polymers.     

Investigation on Mechanism for Separation of Alkali, Alkaline Metal and Ammonium Cations in Nonaqueous Capillary Electrophoresis

Capillary electrophoresis ( CE ) has rapidly gained great interests among researchers in many different fields. One of these areas is the separation of small ions such as inorganic cations, anions, and low Mr organic molecules However, as the separation of ions     

毛细管电泳及其质谱联用技术分析重组人促红细胞生成素

用高效毛细管电泳测定了重组人促红细胞生成素（ｒｈＥＰＯ）的微多相性、肽图，同时采用毛细管电泳质谱联用技术鉴定了部分非糖基化胰酶消解片段和Ｏ－１２６糖基化肽的结构。方法简便、快速，适用于ｒｈＥＰＯ半成品的质量控制。     

苯酚与苯二酚的胶束电动毛细管色谱分离研究

用十二烷基硫酸负作胶束，分别在磷酸二氢钠和硼砂缓冲体系中，分离了苯酚与苯二酚的３种同分异构体，详细研究了不同背景电解质同离子体系中，胶束浓度与流动相ｐＨ值对分离效率的影响，优化条件下４ｍｉｎ内完成了苯酚与苯二酚３种异构体的分离，分离效率及理论塔板数为２．１×１０＾５～３．１×１０＾５／ｍ，保留时间相对标准偏差在２．６％以内，峰高定量分析精度在３．１％以内。     

人体基因组课题（HGP）计划给分析化学带来的挑战与机会

本文综述了在ＤＮＡ测序方面分析化学的最新进展，包括电泳，毛细管电泳（ＣＥ），质谱（ＭＳ），电喷雾电离－质谱（ＥＳＩ－ＭＳ），荧光光谱、共振离子谱（ＲＩＳ）和单分子测定，同时还叙述了两维技术和多段测序方法的进展。     

应用毛细管电泳法分离测定6种取代苯化合物

采用毛细管电泳法对六种取代苯化合物进行了分离研究，考察了3种电泳模式对分离的影响。环糊精的胶束毛细管电泳法可使各组分达到基线分离，正交设计法得到了最佳实验条件，在质量浓度为30－300mg/L的范围内，可进行定量分析，该方法已应用于废液中苯类化合物的测定。     

Analytical potential of enzyme-coated capillary reactors in capillary zone electrophoresis

Enzymes immobilized on the inner surface of an electrophoretic capillary were used to increase sensitivity and resolution in capillary zone electrophoresis (CZE). Sensitivity is enhanced by inserting a piece of capillary containing the immobilized enzyme into the main capillary, located before the detector, in order to transform the analyte into a product with a higher absorptivity. This approach was used to determine ethanol. In order to improve resolution, capillary pieces containing immobilized enzymes were inserted at various strategic positions along the electrophoretic capillary. On reaching the enzyme, the analyte was converted into a product with a high electrophoretic mobility, the migration time for which was a function of the position of the enzyme reactor. This approach was applied to the separation and determination of acetaldehyde and pyruvate. Finally, the proposed method was validated with the determination of ethanol, acetaldehyde, and pyruvate in beer and wine samples.     

气相法分析化妆品中的防腐剂

 采用大口径中极性毛细管柱HP 170 1(15m× 0 5 3mmi d × 1 0 μm)对苯甲醇、对羟基苯甲酸甲酯、对羟基苯甲酸乙酯、对羟基苯甲酸丙酯和对羟基苯甲酸丁酯等化妆品中常用的 5种防腐剂进行了气相分析方法研究。结果表明 ,该毛细管柱能够很好地分离这 5种化合物 ,抗干扰性良好 ,其检出限分别是 13ng ,70ng ,70ng ,10 0ng和 10 0ng ,线性范围为 5 0ng～ 5 0 0ng。     

On the stability of micro-LC columns (packed fused silica capillary columns)

The life expectancy and resistance to flow, pressure shocks, solvent gradients, and bending of packed fused silica capillary columns (Micro-LC) are discussed.     

Hybrid discrete-continuum model of tumor growth considering capillary points

A hybrid discrete-continuum model of tumor growth in the avascular phase considering capillary points is established. The influence of the position of capillary points on tumor growth is also studied by simulation. The results of the dynamic tumor growth and the distribution of oxygen, matrix-degrading enzymes, and extracellular matrixconcentration in the microenvironment with respect to time are shown by graphs. The relationships between different oxygenated environments and the numbers of surviving, dead, proliferative, and quiescent tumor cells are also investigated.