Wide-scope screening of polar contaminants of concern in water: A critical review of liquid chromatography-high resolution mass spectrometry-based strategies

The number of chemicals with potential to reach the environment is still largely unknown, which poses great challenges for both environmental scientists and analytical chemists. Liquid chromatography coupled to high-resolution mass spectrometry (LC-HRMS) is currently the instrumentation of choice for identification of wide-scope polar chemicals of concern (CECs) in water. This review critically evaluates all steps involved in screening for polar CECs in water, including sampling and extraction, analysis by LC-HRMS, data (pre-)treatment, evaluation and reporting. Passive samplers and direct injection, in combination with LC-HRMS, provide new opportunities compared with conventional grab water sampling, as do instrumental advances such as ion-mobility spectrometry coupled to HRMS (IM-HRMS). In this paper, we argue that target, suspect and non-target screening should not be viewed as three separate principles, but rather as conceptual approaches to general data treatment strategies that can be linked together. Due to the large amount of data generated, smart prioritisation strategies are needed, in particular for non-target screening, to reduce complexity and focus on data of high interest. We critically evaluate existing strategies and consider that each prioritisation step will result in data loss (as any other step in a screening study), requiring compromises depending on the research question to be tackled. Many different data treatment strategies have been developed in recent years, but structure elucidation remains a challenging and time-consuming task. We discuss current and potential future trends, e.g. effect-based methods that can be used as future prioritisation tools, technological advances like IM-HRMS and improved software solutions that can enable new data treatment strategies.     

大气环境下的钢筋混凝土桥梁时变可靠度分析

为了探究钢筋混凝土桥梁抗力退化对桥梁可靠性能的影响,综合考虑一般大气环境下混凝土强度、钢筋强度、混凝土与钢筋黏结性能的降低,建立普通钢筋混凝土桥梁的抗力退化时变模型,分析规范车辆荷载作用的桥梁时变可靠度。研究结果表明,(1)一般大气环境下,桥梁抗力随着服役时间的增加而减小,其中钢筋强度退化对桥梁抗力的影响最大,其次是钢筋与混凝土黏结性能降低,而混凝土强度退化对桥梁抗力的影响相对较小; (2)桥梁可靠指标随着服役时间的增加而减小,密集行车占比越大,桥梁承载能力失效的概率就越大;非平稳车载作用下的桥梁可靠指标小于平稳车载,桥梁需要维修补强的时间比平稳车载提前; (3)多梁式简支梁桥在建造时应该提高边梁的安全储备,在管养时可以采取限载措施进行干预。     

Persistent Random Walks in Stationary Environment

We study the behavior of persistent random walks (RW) on the integers in a random environment. A complete characterization of the almost sure limit behavior of these processes, including the law of large numbers, is obtained. This is done in a general situation where the environmental sequence of random variables is stationary and ergodic. Szász and Tóth obtained a central limit theorem when the ratio /, of right- and left-transpassing probabilities satisfies /a<1 a.s. (for a given constant a). We consider the case where / has wider fluctuations; we shall observe that an unusual situation arises: the RW may converge a.s. to infinity even with zero drift. Then, we obtain nonclassical limiting distributions for the RW. Proofs are based on the introduction of suitable branching processes in order to count the steps performed by the RW.     

软件复用技术实现策略研究

首先分析和提出了一种基于ＯＷＥ（ＯｂｊｅｃｔＷｉｔｈ Ｅｖｅｎｔ）的软构件描述方法,然后深入探讨了如何利用面向对象方法实现软件复用的策略,最后着重分析了继承机制对软件复用的支持以及在分布处理环境中的改进方案．     

N-乙基-1,10-菲罗啉-2-甲胺镍(Ⅱ)配合物的合成、晶体结构及性质研究

0IntroductionPhenanthrolinederivativescontainingaminegroupshavebothsoftandhardsitesandaregooddonorsformetalions.1,10鄄phenanthrolineanditsderivativeshavebeenextensivelyusedasligandsinbothanalyticalandpreparativecoordinationchemis鄄try[1].Mostoftheseworksh…     

现代地貌过程中的人类作用

人为的风化、侵蚀、搬运、堆积、造貌等作用，是现代地貌过程中一种新的营力。这种作用的强度主要取决于人口、社会经济发展水平、科学技术水平等因素。而人为地貌作用导致的地貌环境变化又会对人类社会发展产生正负两方面的影响，尤其是其负面影响常常会产生与人们的主观愿望相反的效果。因此，必须根据可持续发展战略来处理人类与地貌环境的关系。     

A martingale approach to directed polymers in a random environment

The diffusive behavior for a system of directed polymers in a random environment was first rigorously discussed by Imbrie and Spencer, and then by Bolthausen. By means of some basic properties of martingales we extend some results due to Imbrie and Spencer concerning the asymptotic behaviour of the mean square displacement. We also obtain a Wiener process behaviour with probability one for this system. Bolthausen already used some martingale limit theorems to prove a central limit theorem for this system.Partly supported by AvH Foundation.     

Some concepts of positive dependence for bivariate interchangeable distributions

In this work we consider some familiar and some new concepts of positive dependence for interchangeable bivariate distributions. By characterizing distributions which are positively dependent according to some of these concepts, we indicate real situations in which these concepts arise naturally. For the various families of positively dependent distributions we prove some closure properties and demonstrate all the possible logical relations. Some inequalities are shown and applied to determine whether under- (or over-) estimates, of various probabilistic quantities, occur when a positively dependent distribution is assumed (falsely) to be the product of its marginals (that is, when two positively dependent random variables are assumed, falsely, to be independent). Specific applications in reliability theory, statistical mechanics and reversible Markov processes are discussed. This work was partially supported by National Science Foundation GP-30707X1. It is part of the author's Ph.D. dissertation prepared at the University of Rochester and supervised by A. W. Marshall. Now at Indiana University.     

Photophysics of the Lanthanide Complexes with Conjugated Carboxylic Acids by Low Temperature Fluorescent Spectroscopy

In the context, some lanthanide (Eu³⁺, Tb³⁺ and Sm³⁺) complexes with conjugated carboxylic acids (pyridine-carboxylic acids derivatives) have been synthesized and characterized. The low temperature fluorescent spectra for these complexes have been measured at nitrogen atmosphere (77 K), indicating that the central Ln³⁺ ions locate in an equivalent coordination environment with low symmetry for most of these lanthanide complexes belonging to dimeric or polymeric structure. Therefore, the electronic dipole transition (supersensitive transition) (⁵D₀ → ⁷F₂ for Eu³⁺, ⁵D₄ → ⁷F₆ for Tb³⁺, ⁴G_5/2 → ⁶H_9/2 for Sm³⁺) and magnetic dipole transition (⁵D₀ → ⁷F₁ for Eu³⁺, ⁵D₄ → ⁷F₅ for Tb³⁺, ⁴G_5/2 → ⁶H_5/2 for Sm³⁺) show the regular change in the corresponding split number of fluorescent spectra, which can be realized to predict the fine structure of lanthanide complexes.