排序方式: 共有80条查询结果,搜索用时 15 毫秒
61.
Dr. Zhi-Yuan Zhang Wen-Wen Xu Wen-Shi Xu Jie Niu Xiao-Han Sun Prof. Dr. Yu Liu 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2020,132(42):18907-18913
An enhancement strategy is realized for ultralong bright room-temperature phosphorescence (RTP), involving polymerization between phosphor monomers and acrylamide and host–guest complexation interaction between phosphors and cucurbit[6,7,8]urils (CB[6,7,8]). The non-phosphorescent monomers exhibit 2.46 s ultralong lifetime after copolymerizing with acrylamide. The improvement is due to the rich hydrogen bond and carbonyl within the polymers which promote intersystem crossing, suppress nonradiative relaxation and shield quenchers effectively. By tuning the ratio of chromophores, a series of phosphorescent copolymers with different lifetimes and quantum yields are prepared. The complexation of macrocyclic hosts CB[6,7,8] promote the RTP of polymers by blocking aggregation-caused quenching, and offsetting the losses of aforementioned interaction provided by polymer. Multiple lifetime-encoding for digit and character encryption are achieved by utilizing the difference of their lifetimes. 相似文献
62.
Noncovalent Chirality Sensing Ensembles for the Detection and Reaction Monitoring of Amino Acids,Peptides, Proteins,and Aromatic Drugs 下载免费PDF全文
Dr. Frank Biedermann Prof. Dr. Werner M. Nau 《Angewandte Chemie (International ed. in English)》2014,53(22):5694-5699
Ternary complexes between the macrocyclic host cucurbit[8]uril, dicationic dyes, and chiral aromatic analytes afford strong induced circular dichroism (ICD) signals in the near‐UV and visible regions. This allows for chirality sensing and peptide‐sequence recognition in water at low micromolar analyte concentrations. The reversible and noncovalent mode of binding ensures an immediate response to concentration changes, which allows the real‐time monitoring of chemical reactions. The introduced supramolecular method is likely to find applications in bioanalytical chemistry, especially enzyme assays, for drug‐related analytical applications, and for continuous monitoring of enantioselective reactions, particularly asymmetric catalysis. 相似文献
63.
Flavylium Network of Chemical Reactions in Confined Media: Modulation of 3′,4′,7‐Trihydroxyflavilium Reactions by Host–Guest Interactions with Cucurbit[7]uril 下载免费PDF全文
In moderately acidic aqueous solutions, flavylium compounds undergo a pH‐, and in some cases, light‐dependent array of reversible chemical reactions. This network can be described as a single acid–base reaction involving a flavylium cation (acidic form) and a mixture of basic forms (quinoidal base, hemiketal and cis and trans chalcones). The apparent pK′a of the system and the relative mole fractions of the basic forms can be modulated by the interaction with cucurbit[7]uril. The system is studied by using 1H NMR spectroscopy, UV/Vis spectroscopy, flash photolysis, and steady‐state irradiation. Of all the network species, the flavylium cation possesses the highest affinity for cucurbit[7]uril. The rate of interconversion between flavylium cation and the basic species (where trans‐chalcone is dominant) is approximately nine times lower inside the cucurbit[7]uril. 相似文献
64.
Jing Wu Lyle Isaacs Prof. Dr. 《Chemistry (Weinheim an der Bergstrasse, Germany)》2009,15(43):11675-11680
Complexation of yellow diaminoazobenzenes 1 and 3 inside cucurbit[7]uril (CB[7]) results in the formation of purple‐colored CB[7] ? cis‐ 1? 2 H+ and CB[7] ? cis‐ 3? 2 H+ complexes, respectively. The high binding affinity and selectivity displayed by CB[7] toward 1 and 3 pays the >10 kcal mol?1 thermodynamic cost for this isomerization. We investigated the behavior of these complexes as a function of pH and observed large pKa shifts and high pH responsiveness, which are characteristic of cucurbit[n]uril molecular containers. The remarkable yellow to purple color change was utilized in the construction of an indicator displacement assay for biologically active amines 4 – 10 . This indicator displacement assay is capable of quantifying the pseudoephedrine ( 5 ) content in Sudafed tablets over the 5–350 μM range. 相似文献
65.
Pedro Montes‐Navajas Laura C. Damonte Dr. Hermenegildo García Prof. Dr. 《Chemphyschem》2009,10(5):812-816
Positron lifetime spectroscopy serves to determine the void volumes of cucurbituril (CB) capsules, which are not amenable to standard gas adsorption methods. In the case of the host–guest complex Au§CB[7], it also provides evidence of the inclusion of gold nanoparticles in the CB cavity (see space‐filling model; Au golden, C gray, H cyan, N blue, O red).
66.
Cooperative Self‐Assembly of a Quaternary Complex Formed by Two Cucurbit[7]uril Hosts,Cyclobis(paraquat‐p‐phenylene), and a “Designer” Guest 下载免费PDF全文
Dr. Mohammad Hossein Tootoonchi Gaurav Sharma Jonathan Calles Prof. Dr. Rajeev Prabhakar Prof. Dr. Angel E. Kaifer 《Angewandte Chemie (International ed. in English)》2016,55(38):11507-11511
The self‐assembly in aqueous solution of the well‐known cyclophane, cyclobis(paraquat‐p‐phenylene) (BB4+), and two cucurbit[7]uril (CB7) hosts around a simple hydroquinol‐based, diamine guest (GH22+) was investigated by 1H NMR and electronic absorption spectroscopies, electrospray mass spectrometry and DFT computations. The formation of a quaternary supramolecular assembly [GH22+?BB4+? (CB7)2] was shown to be a very efficient process, which takes place not only because of the attractive forces between each of the hosts and the guest, but also because of the lateral interactions between the hosts in the final assembly. This complementary set of attractive interactions results in clear cooperative binding effects that help overcome the entropic barriers for multiple component assembly. 相似文献
67.
Mezzina E Cruciani F Pedulli GF Lucarini M 《Chemistry (Weinheim an der Bergstrasse, Germany)》2007,13(25):7223-7233
EPR spectroscopy was used for the first time to explore the binding properties of cucurbit[7]uril (CB7), a representative member of the cucurbituril family. Evidence for the formation of a complex between nitroxide radicals and the host system in an aqueous solution was provided by large changes in the nitrogen hyperfine splitting, attributed to the different polar environments experienced by the included radical. In the presence of alkali cations, the EPR spectra of benzyl tert-butyl nitroxide were characterised by new signals attributed to the radical hosted in the CB7 cavity in which one metal cation is in close contact with the nitroxidic oxygen. The formation of the coordination complex results in a substantial increase in the electron spin density on the nitrogen in inverse order with respect to the size of the cation owing to increased localisation of negative charge on the oxygen atom from bonding to the alkali cation. The EPR spectra showed selective line-broadening effects as a result of metal exchange between bulk water and the coordination complex. Analysis of the EPR linewidth variations allowed us to measure the corresponding kinetic rate constants for the first time. NMR spectroscopy showed that this behaviour is not peculiar to nitroxides but is also exhibited by the related carbonyl compounds. These data allowed us to quantify the template effect and to reach the conclusion that, in the presence of a guest having a coordinating lone pair, the formation of ternary metal-guest-CB complexes must be taken into account when discussing the complexation behaviour of cucurbituril derivatives in the presence of salts. 相似文献
68.
Pedro Ferreira Dr. Barbara Ventura Dr. Andrea Barbieri Dr. José P. Da Silva Dr. César A. T. Laia Dr. A. Jorge Parola Dr. Nuno Basílio 《Chemistry (Weinheim an der Bergstrasse, Germany)》2019,25(14):3477-3482
The discovery of stimuli-responsive high affinity host–guest pairs with potential applications under biologically relevant conditions is a challenging goal. This work reports a high-affinity 1:1 complex formed between cucurbit[8]uril and a water-soluble photochromic diarylethene derivative. It was found that, by confining the open isomer within the cavity of the receptor, a redshift in the absorption spectrum and an enhancement of the photocyclization quantum yield from Φ=0.04 to Φ=0.32 were induced. This improvement in the photochemical performance enables quantitative photocyclization with visible light that, together with the near-infrared light-induced ring-opening reaction and the 100-fold selectivity for the closed isomer, confirms this as an outstanding light-responsive affinity pair. 相似文献
69.
Anastasia Grishina Dr. Stancho Stanchev Lukáš Kumprecht Dr. Miloš Buděšínský Dr. Michaela Pojarová Dr. Michal Dušek Dr. Michaela Rumlová Ivana Křížová Dr. Lubomír Rulíšek Dr. Tomáš Kraus 《Chemistry (Weinheim an der Bergstrasse, Germany)》2012,18(39):12292-12304
New tubular host molecules, which are composed of two β‐cyclodextrin macrocycles that are connected through two disulfide bonds, have been prepared by the air‐promoted oxidation of 6I,6IV‐dideoxy‐6I,6IV‐disulfanyl‐β‐cyclodextrin in aqueous solution. This reaction leads to three products: monomeric intramolecular disulfide and two dimeric species, which are termed as “non‐eclipsed” and “eclipsed” cyclodextrin duplexes. Oxidation at a concentration of the starting thiol of 0.1 mM gave the intramolecular disulfide as the major product whereas a concentration in the millimolar range afforded the dimeric species as the dominant products. The tubular structure of the “non‐eclipsed” isomer was unequivocally determined by X‐ray analysis. The binding affinities of the duplexes to a wide range of compounds, including fluorescent dyes and clinically used drugs Imatinib and Esomeprazol, were studied in water by ITC. For most guest compounds, the experimentally determined Ka values were in the range 107–108 M ?1. These binding affinities are significantly higher than those found in the literature for analogous complexes with native cyclodextrins. In cases of binding of neutral or anionic guest molecules cyclodextrin duplexes outperformed cucurbiturils. A complex between a duplex and Nile blue was used to investigate its ability to penetrate the cytoplasmic membrane of HeLa cells. We found that the complex accumulated in the cell membrane but did not pass into cytosol. Importantly, the complex did not decompose to a significant extent under high dilution in the cellular environment. 相似文献
70.