Microwave activated synthesis of 2-aryl-quinazolin-4（3H）ones

A highly efficient synthesis of 2-aryl-quinazolin-4(3H)ones was performed by one-pot oxidative heterocyclization of 2- aminobenzamide with aldehydes in the presence of potassium permanganate in dimethylacetamide under microwave irradiation.     

Facile and efficient synthesis of 2-substituted-N1-carbethoxy-2, 3-dihydro-4(1H)-quinazolinones in fluorous solvent

A facile, efficient and novel approach to access 2-substituted-N1-carbethoxy-2,3-dihydro-4(1H)-quinazolinones was developedby condensation of substituted N-carbethoxyanthranilamide with alkyl, aromatic or heteroaromatic aldehydes in the refluxing 2,2,2-trifluoroethanol or hexafluoroisopropanol using p-toluenesulfonic acid as catalyst.? 2008 Bai Ling Xu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.