全文获取类型
收费全文 | 5335篇 |
免费 | 573篇 |
国内免费 | 702篇 |
专业分类
化学 | 5048篇 |
晶体学 | 19篇 |
力学 | 251篇 |
综合类 | 102篇 |
数学 | 549篇 |
物理学 | 641篇 |
出版年
2024年 | 11篇 |
2023年 | 58篇 |
2022年 | 107篇 |
2021年 | 174篇 |
2020年 | 203篇 |
2019年 | 173篇 |
2018年 | 130篇 |
2017年 | 167篇 |
2016年 | 223篇 |
2015年 | 208篇 |
2014年 | 229篇 |
2013年 | 316篇 |
2012年 | 451篇 |
2011年 | 269篇 |
2010年 | 247篇 |
2009年 | 298篇 |
2008年 | 371篇 |
2007年 | 308篇 |
2006年 | 326篇 |
2005年 | 285篇 |
2004年 | 274篇 |
2003年 | 241篇 |
2002年 | 241篇 |
2001年 | 148篇 |
2000年 | 149篇 |
1999年 | 130篇 |
1998年 | 122篇 |
1997年 | 112篇 |
1996年 | 101篇 |
1995年 | 90篇 |
1994年 | 74篇 |
1993年 | 71篇 |
1992年 | 50篇 |
1991年 | 49篇 |
1990年 | 42篇 |
1989年 | 23篇 |
1988年 | 16篇 |
1987年 | 20篇 |
1986年 | 12篇 |
1985年 | 14篇 |
1984年 | 14篇 |
1983年 | 13篇 |
1982年 | 18篇 |
1981年 | 12篇 |
1980年 | 5篇 |
1979年 | 6篇 |
1978年 | 4篇 |
1976年 | 1篇 |
1974年 | 2篇 |
1936年 | 1篇 |
排序方式: 共有6610条查询结果,搜索用时 17 毫秒
41.
In this paper, we consider hypothesis testing problems in which the involved samples are drawn from generalized multivariate modified Bessel populations. This is a much more general distribution that includes both the multivariate normal and multivariate-t distributions as special cases. We derive the distribution of the Hotelling's T2-statistic for both the one- and two-sample problems, as well as the distribution of the Scheffe's T2-statistic for the Behrens–Fisher problem. In all cases, the non-null distribution of the corresponding F-statistic follows a new distribution which we introduce as the non-central F-Bessel distribution. Some statistical properties of this distribution are studied. Furthermore, this distribution was utilized to perform some power calculations for tests of means for different models which are special cases of the generalized multivariate modified Bessel distribution, and the results compared with those obtained under the multivariate normal case. Under the null hypothesis, however, the non-central F-Bessel distribution reduces to the central F-distribution obtained under the classical normal model. 相似文献
42.
Yirang Yuan 《Numerical Methods for Partial Differential Equations》2003,19(5):665-681
For the coupled system of multilayer fluid dynamics in porous media, the modified characteristic finite difference fractional steps method applicable to parallel arithmetic is put forward and two‐dimensional and three‐dimensional schemes are used to form a complete set. Some techniques, such as calculus of variations, energy method, piecewise biquadratic interpolation, multiplicative commutation rule of difference operators, decomposition of high order difference operators and prior estimates are adopted. Optimal order estimates in L2 norm are derived to determine the error in the approximate solution. This method has already been applied to the numerical simulation of multilayer fluid dynamics in porous media. © 2003 Wiley Periodicals, Inc. Numer Methods Partial Differential Eq 19: 665–681, 2003. 相似文献
43.
István Szilágyi László. Horváth Imre Labádi Klara Hernadi István Pálinkó Tamás Kiss 《Central European Journal of Chemistry》2006,4(1):118-134
An imidazolate-bridged copper(II)-zinc(II) complex (Cu(II)-diethylenetriamino-μ-imidazolato-Zn(II)-tris(2-aminoethyl)amine perchlorate (denoted as “Cu,Zn complex”) and a simple copper(II) complex (Cu(II)-tris(2-aminoethyl)
amine chloride (“Cu-tren”) were prepared and immobilised on silica gel (by hydrogen or covalent bonds) and montmorillonite
(by ion exchange). The immobilised substances were characterised by FT-IR spectroscopy and their thermal characteristics were
also studied. The obtained materials were tested in two probe reactions: catalytic oxidation of 3,5-di-tert-butyl catechol (DTBC) (catecholase activity) and the decomposition of hydrogen peroxide (catalase activity). It was found
that the catecholase activity of the Cu,Zn complex increased considerably upon immobilization on silica gel via hydrogen bonds and intercalation by ion exchange among the layers of montmorillonite. The imidazolate-bridged copper(II)-zinc(II)
complex and its immobilised versions were inactive in hydrogen peroxide decomposition. The Cu(II)-tris(2-aminoethyl)amine
chloride complex displayed good catalase activity; however, immobilisation could not improve it. 相似文献
44.
45.
Summary Some stability and convergence theorems of the modified Ishikawa iterative sequences with errors for asymptotically nonexpansive
mapping in the intermediate sense and asymptotically pseudo contractive and uniformly Lipschitzian mappings in Banach spaces
are obtained. 相似文献
46.
O. A. Brezhneva Yu. G. Evtushenko A. A. Tret’yakov 《Computational Mathematics and Mathematical Physics》2006,46(11):1896-1909
The theory of p-regularity is applied to optimization problems and to singular ordinary differential equations (ODE). The special variant of the method of the modified Lagrangian function proposed by Yu.G. Evtushenko for constrained optimization problems with inequality constraints is justified on the basis of the 2-factor transformation. An implicit function theorem is given for the singular case. This theorem is used to show the existence of solutions to a boundary value problem for a nonlinear differential equation in the resonance case. New numerical methods are proposed including the p-factor method for solving ODEs with a small parameter. 相似文献
47.
48.
本文报道了1:12-磷铜杂多酸(PMo_(12)薄膜修饰碳纤维(CF)微电极的制备及其电化学性质。采用简单,快速的浸渍吸附制备的PMo_(12)薄膜修饰CF电极在酸性介质中具有很高的稳定性和氧化还原活性,电解质溶液的pH值和扫描电位范围对PMo_(12)膜的稳定性和电化学性质产生较大的影响。另一方面,PMo_(12)薄膜修饰CF微电极对酸性水溶液中的PMo_(12)和氯酸根离子(ClO)_3~-)的电催化还原作用也进行了描述。 相似文献
49.
M. A. Massiah V. Saraswat H. F. Azurmendi A. S. Mildvan 《Journal of Molecular Structure》2004,700(1-3):247-254
The MutT pyrophosphohydrolase from E. coli (129 residues) catalyzes the hydrolysis of nucleoside triphosphates (NTP), including 8-oxo-dGTP, by substitution at Pβ, to yield NMP and pyrophosphate. The product, 8-oxo-dGMP is an unusually tight binding, slowly exchanging inhibitor with a KD=52 nM, (ΔG°=−9.8 kcal/mol) which is 6.1 kcal/mol tighter than the binding of dGMP (ΔG°=−3.7 kcal/mol). The higher affinity for 8-oxo-dGMP results from a more favorable ΔHbinding (−32 kcal/mol) despite an unfavorable −TΔS°binding (+22 kcal/mol). The solution structure of the MutT–Mg2+-8-oxo-dGMP complex shows a narrowed, hydrophobic nucleotide-binding cleft with Asn-119 and Arg-78 among the few polar residues. The N119A, N119D, R78K and R78A single mutations, and the R78K+N119A double mutant all showed largely intact active sites, on the basis of small changes in the kinetic parameters of dGTP hydrolysis and in 1H–15N HSQC spectra. However, the N119A mutation profoundly weakened the active site binding of 8-oxo-dGMP by 4.3 kcal/mol (1650-fold). The N119D mutation also weakened 8-oxo-dGMP binding but only by 2.1 kcal/mol (37-fold), suggesting that Asn-119 functioned both as a hydrogen bond donor to C8=O, and a hydrogen bond acceptor from N7H of 8-oxo-dGMP, while aspartate at position −119 functioned as an acceptor of a single hydrogen bond. Much smaller weakening effects (0.3–0.4 kcal/mol) on the binding of dGMP and dAMP were found, indicating specific hydrogen bonding of Asn-119 to 8-oxo-dGMP. While formation of the wild type MutT–Mg2+-8-oxo-dGMP complex slowed the backbone NH exchange rates of 45 residues distributed throughout the protein, the same complex of the N119A mutant slowed the exchange rates of only 11 residues at or near the active site, indicating an increase in conformational flexibility of the N119A mutant. The R78K and R78A mutations weakened the binding of 8-oxo-dGMP by 1.7 and 1.1 kcal/mol, respectively, indicating a lesser role of Arg-78 than of Asn-119 in the selective binding of 8-oxo-dGMP, likely donating a single hydrogen bond to its C6=O. The R78K+N119A double mutant weakened the binding of 8-oxo-dGMP (KIslope=3.1 mM) by 6.5±0.2 kcal/mol which overlaps, within error with the sum of the effects of the two single mutants (6.0±0.3 kcal/mol). Such additive effects of the two single mutants in the double mutant are most simply explained by the independent functioning of Asn-119 and Arg-78 in the binding of 8-oxo-dGMP. Independent functioning of these two residues in nucleotide binding is consistent with their locations in the MutT–Mg2+-8-oxo-dGMP complex, on opposite sides of the active site cleft, with a distance of 8.4±0.5 Å between their side chain nitrogens. 相似文献
50.
聚中性红膜修饰电极的电化学特性及其电催化性能 总被引:35,自引:5,他引:35
研究了中性红在玻碳电极表面电聚合成膜的方法和条件,对膜内电荷传输过程和电化学特性分别用循环伏安技术和电位阶跃暂态技术进行了初步探讨。该膜对维生素C和亚硝酸盐有较强的电催化作用,催化电流与底物浓度在很宽的范围内呈线性关系,可用于实际样品的分析。 相似文献