An Efficient One-Pot Synthesis of Nitriles from Carboxylic Acids Without Solvent Under Microwave Irradiation

Nitriles were prepared from alkyl and aryl carboxylic acids in dry media conditions, under microwave irradiation. Heating of the carboxylic acid, urea and amidosulfonic acid adsorbed on alumina support in a microwave oven affords nitriles in 20–93% yields.     

Oxidation of Benzylic Alcohols to Carbonyl Compounds with Potassium Permanganate in Ionic Liquids

Abstract

The selective oxidation of primary and secondary benzylic alcohols with potassium permanganate in ionic liquids to give corresponding aldehydes and ketones in 83–97% yields has been described.     

Oxone as a Mild,Inexpensive, and Environmentally Benign Oxidant for the α-Thiocyanation of Ketones

An efficient and direct approach for the α-thiocyanation of ketones with α-hydrogens has been developed using ammonium thiocyanate as a thiocyanating agent and oxone as an oxidant in methanol.     

Activation of Iron (III) and Bismuth (III) Nitrates by Tungstophosphoric Acid: Solvent‐Free Oxidative Deprotection of Oximes to Carbonyl Compounds

Abstract

Tungstophosphoric acid (H₃PW₁₂O₄₀ · 6H₂O) has been used as a catalyst for a simple, rapid, selective, and solvent‐free cleavage of oximes to carbonyl compounds using iron (III) and bismuth (III) nitrates as oxidants.     

Rhodium(II) catalyzed highly diastereoselective synthesis of conformationally restricted dispiro[1,3-dioxolane]bisoxindoles

Synthesis of conformationally restricted dispiro- and bis-dispiro-1,3-dioxolanes via three-component reaction of diazoamides, ketoamides/diketones, and aromatic/heteroaromatic aldehydes in the presence of rhodium(II) acetate dimer catalyst at room temperature involving carbonyl ylides is demonstrated with diastereoselectivity. Synthesis of macrocyclic dispiro-1,3-dioxolanes via intramolecular carbonyl ylide is also delineated in high yield. The conformationally restricted symmetrical as well as unsymmetrical dispiro-1,3-dioxolanes were obtained under mild conditions in a highly diastereo- and regioselective manner.     

单取代芳烃对位选择性碳氢活化反应研究

以单取代芳烃为芳基化试剂,以羰基为导向定位基团,研究了单取代芳烃对位选择性与芳香酮的交叉脱氢偶联反应。该方法的高选择性一方面体现在用作芳基化试剂的单取代芳烃能够单一选择性地发生对位碳氢活化,并生成对位取代产物;另一方面,作为弱导向基团的羰基具有优异的邻位导向定位作用,高选择性地发生羰基邻位碳氢键活化。此外,该方法还具有反应条件温和、反应效率高、底物范围广、氧化剂廉价易得等优点,为对位取代联芳基化合物的合成提供了一条切实可行的途径。     

Selective alcohol oxidation catalysed BY FeCl3 /novel glycine functionalised IONIC liquid

An effective and eco-friendly technique were designated for quick alcohol oxidation by glycine functionalised imidazolium ionic liquids in presence of FeCl₃ at ambient-temperature. No over the primary alcohols oxidation to carbonyl compounds was observed in presence of this FeCl₃/[Gmim]Cl. These benefits of the catalyst resulted mainly from the circumstance with alcohols-H₂O₂, and the Fe³⁺ was coordinated by the immobilized IL to permitted both reactants to access the active sites of the catalyst effectively. The catalyst recycled nine times without loss of activity.     

Triruthenium clusters containing mono and bidentate phosphines: Synthesis,structure, thermal reactivity and fluxional behavior

The syntheses, structures and thermal reactions of [Ru₃(CO)₉{P(C₄H₃E)₃}(μ-dppe)] (2, E = S; 3, E = O; dppe = 1,2-bis(diphenylphosphino)ethane) are described. These triphosphine-substituted clusters can be easily obtained in high yield from the Me₃NO initiated room temperature reaction between [Ru₃(CO)₁₀(μ-dppe)] (1) and P(C₄H₃E)₃. Both clusters have been structurally characterized which reveals that the functionalized phosphine P(C₄H₃E)₃ is coordinated to the remote ruthenium atom using the phosphorus atom, while the NMR spectroscopic data indicate that both clusters are fluxional in solution mainly due to the ring-flipping process involving the dppe ligand which has been probed by VT NMR spectroscopy. Thermolysis of 2 at 66 °C affords 1 via P(C₄H₃S)₃ dissociation, whilst that of 3 under similar experimental conditions also furnishes the diruthenium σ,π-furyl complex [Ru₂(CO)₆(μ,η²-C₄H₃O){μ-P(C₄H₃O)₂] (4) in addition to 1.     

电催化醇选择性氧化为醛酮的研究进展

醇选择性氧化为相应的羰基化合物是有机化学中最常用的生成羰基化合物的反应,电催化氧化具有反应条件温和、环境友好等优点,是一种非常有前途的醇催化氧化绿色生产工艺。本文综述了直接和间接电催化氧化反应的方法,并对各类体系的催化效果进行了简要介绍。     

Synthesis and Molecular Structure of [Ru3(CO)10(μ-dppa)] (dppa = Ph2PN(H)PPh2) Provided by Its Dioxane Solvate

The sodium benzophenone ketyl-induced reaction of [Ru₃(CO)₁₂] with bis(diphenylphosphanyl)amine Ph₂PN(H)PPh₂ (dppa) in THF resulted in the formation of the expected metal cluster [Ru₃(CO)₁₀(μ-dppa)] ( 1 ) in high yield. 1 was fully characterized by spectroscopic means and crystals of the compound suitable for X-ray diffraction were obtained from dichloromethane/dioxane. The molecular structure of 1 as its dioxane solvate was determined by X-ray crystallography. The compound crystallized in a new crystal structure of [Ru₃(CO)₁₀(μ-dppa)] in the triclinic space group P1 , whereas that compound was described in an earlier report crystallizing from chloroform in the monoclinic space group P2₁/c.