dbHDPLS: A database of human disease-related protein-ligand structures

Protein-ligand complexes perform specific functions, most of which are related to human diseases. The database, called as human disease-related protein-ligand structures (dbHDPLS), collected 8833 structures which were extracted from protein data bank (PDB) and other related databases. The database is annotated with comprehensive information involving ligands and drugs, related human diseases and protein-ligand interaction information, with the information of protein structures. The database may be a reliable resource for structure-based drug target discoveries and druggability predictions of protein-ligand binding sites, drug-disease relationships based on protein-ligand complex structures. It can be publicly accessed at the website: http://DeepLearner.ahu.edu.cn/web/dbDPLS/.     

FAIR二极超导磁体样机结构稳定性的初步研究

冷质部件的支撑是FAIR二极超导磁体样机中的关键部件,它们对于保持线圈的空间位形起到至关重要的作用,因此,对其开展稳定性的研究是十分必要的。为此,文中基于压杆稳定的理论和有限元法,对支撑进行了稳定性的研究,为支撑力学性能的评估、结构的优化设计和磁体样机的工程设计提供了参考依据。     

物理实验教学中本科生创新能力培养的实践与探索

主要探讨安徽大学基础物理实验教学中心在物理实验教学中增强学生创新意识和提高创新能力.     

基于Theil不等系数的加权几何平均组合预测模型的性质

加权几何平均组合预测为一种非线性的组合预测方法。本文提出了基于Theil不等系数的加权几何平均的组合预测模型,针对该模型定义了优性组合预测、预测方法优超和组合预测冗余度等新的概念;探讨了非劣性组合预测和优性组合预测存在的充分条件;给出了一个冗余预测方法出现的判定定理。     

The solution of Kato's conjectures

In this Note, we announce the solution of Kato's conjectures about the domain of square roots of differential elliptic operators in the Euclidean space or a Lipschitz domain.     

Hopf bifurcation and chaos in a single delayed neuron equation with non-monotonic activation function

A simple neural network model with discrete time delay is investigated. The linear stability of this model is discussed by analyzing the associated characteristic transcendental equation. For the case with inhibitory influence from the past state, it is found that Hopf bifurcation occurs when this influence varies and passes through a sequence of critical values. The stability of bifurcating periodic solutions and the direction of Hopf bifurcation are determined by applying the normal form theory and the center manifold theorem. Chaotic behavior of a single delayed neuron equation with non-monotonously increasing transfer function has been observed in computer simulation. Some waveform diagrams, phase portraits, power spectra and plots of the largest Lyapunov exponent will also be given.     

Two-parameter quantum deformation of Lie superalgebras

It is known that the quantum deformation of the enveloping superalgebra corresponding to the structure of the corresponding quantum group is given by a simple root system of the corresponding algebra. In this work we attempt to make a two-parameter quantum deformation in the non-standard simple root system with two odd simple roots.     

HREELS study of C70 molecules adsorbed on a Si(1 1 1)-(7×7) surface

We have measured the coverage dependence of vibrational excitation spectra of C₇₀ molecules adsorbed on a Si(1 1 1)-(7×7) surface using high-resolution electron-energy-loss spectroscopy. At the monolayer coverage, the intensity of the 57 meV peak increases, and those of the 83 and 178 meV peaks decrease. Taking into account the dipole selection rule, the change in intensity of the 57 meV peak indicates that the average angle between the long axes of C₇₀ molecules and surface normal is about 40°. The decreases in intensities of the 83 and 178 meV peaks suggest that the rotational motion of molecules is quenched upon adsorption. We will discuss the Coriolis interaction between the accidentally degenerate A₂″ and E₁′ modes.