Increased variability in performance has been associated with the emergence of several neurological and psychiatric pathologies. However, whether and how consistency of neuronal activity may also be indicative of an underlying pathology is still poorly understood. Here we propose a novel method for evaluating consistency from non-invasive brain recordings. We evaluate the consistency of the cortical activity recorded with magnetoencephalography in a group of subjects diagnosed with Mild Cognitive Impairment (MCI), a condition sometimes prodromal of dementia, during the execution of a memory task. We use metrics coming from nonlinear dynamics to evaluate the consistency of cortical regions. A representation known as parenclitic networks is constructed, where atypical features are endowed with a network structure, the topological properties of which can be studied at various scales. Pathological conditions correspond to strongly heterogeneous networks, whereas typical or normative conditions are characterized by sparsely connected networks with homogeneous nodes. The analysis of this kind of networks allows identifying the extent to which consistency is affected in the MCI group and the focal points where MCI is especially severe. To the best of our knowledge, these results represent the first attempt at evaluating the consistency of brain functional activity using complex networks theory. 相似文献
A three-dimensional (3D) finite element model of air-cushion isolated arch dam is presented with the nonlinear gas-liquid-solid multi-field dynamic coupling effect taken into account.In this model,the displacement formulation in Lagrange method,pressure formulation in Euler method,nonlinear contact model based on Coulomb friction law are applied to the air-cushion,reservoir and contraction joint domain,respectively.The dynamic response of Jinping I arch dam with a height of 305 m is analyzed using the seismic records of the Wenchuan Earthquake in 2008.Numerical results show that the air-cushion isolation reduces significantly the hydrodynamic pressure as well as the opening width for the contraction joints of high arch dam. 相似文献
This paper is a continuation of an earlier paper [P.E. Hancock, Velocity scales in the near-wall layer beneath reattaching turbulent separated and boundary layer flows, Eur. J. Mech. B Fluids 24 (2005) 425–438] in which it is proposed that each Reynolds stress has its own velocity scale. Two of these, and , are directly related by definition to the r.m.s. of the wall-shear-stress fluctuations ( and ) in the streamwise and transverse directions. They are also velocity scales for the true dissipation of the turbulent kinetic energy and the Kolmogorov velocity and length scales at the surface. From asymptotic considerations it is shown that the other two scales are related to averages involving instantaneous gradients of wall-shear-stress fluctuations. The measurements, made using pulsed-wire anemometry into the viscous sublayer, show that and are also the velocity scales for the respective streamwise and transverse fourth-order velocity moments, together with the viscous velocity scale (). Normalised, the fourth-order moments show an inner-layer-like behaviour independent of both position and direction, like that seen in the second-order moments [P.E. Hancock, Velocity scales in the near-wall layer beneath reattaching turbulent separated and boundary layer flows, Eur. J. Mech. B Fluids 24 (2005) 425–438]. However, not surprisingly, the third order moments exhibit an effect of mean shear, seen in the skewing of the probability distributions. Though not measured directly, the measurements imply the behaviour of the averaged products of fluctuations in wall-shear-stress and wall-pressure-gradient ( and ). Normalised, they also are independent of position and direction. Some of the results presented apply more generally to the near-wall region beneath turbulent flow. 相似文献
Located between the Tarim platform and Junggar massif, the West Tianshan intracontinental rift abuts against the China-Kazakhstan boundary in the west part, borders on the Yilianha-bierga late Paleozoic relic ocean basin and the South Tianshan late Paleozoic ocean basin respectively in the northeast separated by the Aibi Lake fault and in the southeast by the fault along the southern margin of the Yili massif. During the development and after the close of the West Tianshan intracontinental rifting in the Carboniferous-Permian period, a series of nonferrous and precious metal mineralizations occurred with the Au-Cu deposits being the most important. Isotopic chronologic study of representative deposits of different types shows that gold-copper mineralization in the West Tianshan intracontinental rift zone mainly happened during the middle-late Her-cynian Period, among which the Axi volcanic hydrothermal type gold deposit was formed during the Carboniferous with a fluid inclusion Rb-Sr isochron age of (339 ± 28) Ma; the Qiabukanzhuota quartzolite type gold deposit has a Rb-Sr isochron age of (312 ± 46) Ma; the Tawuerbieke porphyry type gold deposit has a Rb-Sr isochron age of (295 ± 16) Ma; the Jingbulak magmatic liquation Cu-Ni deposit and the Musizaote porphyry type Cu deposit have the forming ages of 300 Ma± and 250 Ma±, respectively. Analyses of crustal evolution and metallogenetic geological backgrounds of Au-Cu mineralizations in the studied area shows a close correlation with the rifting.