Asymmetric synthesis of 5,6-dehydrosenedigitalene using lipase-catalyzed highly enantioselective transesterification of a primary alcohol with vinyl 3-(4-trifluoromethylphenyl)propanoate

The highly enantioselective kinetic resolution of a racemic primary alcohol by lipase-catalyzed transesterification with vinyl 3-(4-trifluoromethylphenyl)propanoate afforded an enantiomerically pure primary alcohol. The versatility of this approach is shown in the asymmetric synthesis of 5,6-dehydrosenedigitalene (R)-1.     

Electrochemical study of the interaction between cytochrome P450sccK201E and cholesterol

Cytochrome P450sccK201E, mutated form of cytochrome P450scc native recombinant (P450sccNR), was employed to study the enzyme–substrate interaction. The detection of the cholesterol was performed by electrochemical method using cyclic voltammetry (CV) and chronoamperometry measurements. The biochemical analysis was realized to observe the electrochemical responses of the engineerized enzyme to three different forms of cholesterol: free, low-density lipoprotein (LDL) and high-density lipoproteins (HDL). Compared to cytochrome P450sccNR, the cytochrome P450sccK201E displays a different behavior in the interaction with the substrate detection.

The results show that the engineerized enzyme can be utilized for the cholesterol detection in biosensor field.     

Deduction, Ordering, and Operations in Quantum Logic

We show that in quantum logic of closed subspaces of Hilbert space one cannot substitute quantum operations for classical (standard Hilbert space) ones and treat them as primitive operations. We consider two possible ways of such a substitution and arrive at operation algebras that are not lattices what proves the claim. We devise algorithms and programs which write down any two-variable expression in an orthomodular lattice by means of classical and quantum operations in an identical form. Our results show that lattice structure and classical operations uniquely determine quantum logic underlying Hilbert space. As a consequence of our result, recent proposals for a deduction theorem with quantum operations in an orthomodular lattice as well as a, substitution of quantum operations for the usual standard Hilbert space ones in quantum logic prove to be misleading. Quantum computer quantum logic is also discussed.     

Study of tau-pair production in photon-photon collisions at LEP and limits on the anomalous electromagnetic moments of the tau lepton

Tau-pair production in the process was studied using data collected by the DELPHI experiment at LEP2 during the years 1997 - 2000. The corresponding integrated luminosity is 650 pb^-1. The values of the cross-section obtained are found to be in agreement with QED predictions. Limits on the anomalous magnetic and electric dipole moments of the tau lepton are deduced.Received: 18 September 2003, Revised: 26 March 2004, Published online: 11 May 2004     

The Pauli energy grows exponentially with the electronic localisation

We investigate the Pauli energy in atoms and molecules as a measure of electron localisation. Our results indicate that the Pauli energy has an exponential dependence on the number of localised electrons. This relationship yields to a kinetic energy density expression that depends on the electron density ρ(r) and the pair density ρ₂(r, r′). The proposed equation shows certain advantages over a similar orbital-free kinetic energy functional recently proposed by Delle Site and co-workers. The methodology introduced here is a novel approach for exploring electronic quantities with a partition scheme that might be useful for research in density functional theory.     

Preparation and spectroscopic properties of nanostructured glass-ceramics containing Yb3+, Er3+ ions and Co2+-doped spinel nanocrystals

Transparent glass-ceramics with Yb³⁺, Er³⁺ ions in glass matrix and tetrahedral Co²⁺-doped MgAl₂O₄ nanocrystals were synthesized. XRD patterns and FESEM micrograph of the glass-ceramics showed that MgAl₂O₄ nanocrystals (sizes of 10–20 nm) are uniformly dispersed in SiO₂ glass matrix. Absorption and emission spectra of the glass-ceramics indicated that Yb³⁺, Er³⁺ remain in SiO₂ glass matrix, while Co²⁺ occupied tetrahedral sites in MgAl₂O₄ nanocrystals, and can function as saturable absorber for Er³⁺. Transparent Co²⁺, Yb³⁺, Er³⁺ co-doped glass-ceramics possesses the spectral requirements and should be a potential laser material used for self-Q-switched microchip laser operating at 1.5–1.6 μm.