Stabilization of the Pro-Tyr-Gly-NH2 melanostatin analog on micelles

Inversed AOT micelles have been used as a system to simulate peptide-receptor interaction; they encapsulate an aqueous solution of the melanostatin analog HCl·Pro-Tyr-Gy-NH₂. NOESY indicates that adsorption at the phase boundary causes the peptide to acquire the biologically active _II conformation. The phenyl ring in Tyr is inserted into the cavity formed by the isooctyl moieties of the AOT molecules.Translated from Teoreticheskaya i Éksperimental'naya Khimiya, Vol. 29, No. 1, pp. 74–80, January–February, 1993.     

Local solvability of PDE with constant coefficients

The fundamental result of the paper consists in the following assertion: Let D be an open set in Rⁿ,f £ L₂(D), and let be a distribution in Rⁿ with a compact support, whose Fourier transform satisfies the condition