<Emphasis Type="Italic">Cis</Emphasis>/<Emphasis Type="Italic">trans</Emphasis> Fluorescent Recognition by Naphthalimide Dyes ⊂ CB [7] Assembly

A novel method to recognize cis/trans isomers was studied here. The naphthalimide dye as guest could bind with host cucurbit [7]uril (CB [7]) and 1:1 naphthalimide dye ? CB [7] assembly was formed. Moreover, this assembly was used as a fluorescent probe to recognized Fumaric acid (FA) and maleic acid (MA) via fluorescence titration. Two carboxyls in MA are in the same side, they could form stable interaction with the assembly and the fluorescence intensity decreased obviously when naphthalimide dye ? CB [7] was titrated by MA (nearly quenched in 1.5 equiv). But two carboxyls in FA are in opposite sides, the interaction between FA and the assembly was weak and not stable, and the fluorescence intensity changed inconspicuously when the assembly was titrated by FA.     

Synthesis of selenium/EDTA-derived porous carbon composite as a Li–Se battery cathode

The carbon substrate with unique 3D macroporous structure has been prepared through the immediate carbonization of ethylenediaminetetraacetic acid (EDTA) and KOH mixture. The porous carbon composed of micro- and small mesoporous (2–5 nm) structure has a BET specific surface area of 1824.8 m² g^?1. The amorphous and nanosized Se is uniformly encapsulated into the porous structure of porous carbon using melting diffusion route, and the weight content of Se in target Se/C composite can be as high as ~50 %. As an Li–Se battery cathode, the Se/C composite delivers a reversible (2nd) discharge capacity of 597.4 mAh g^?1 at 0.24C and retains a discharge capacity of 538.4 mAh g^?1 at 0.24C after 100 cycles. Furthermore, the composite also has a stable capacity of 291.0 mAh g^?1 at a high current of 4.8C. The high specific area and good porous size of EDTA-derived carbon substrate may a be responsibility for the excellent electrochemical performances of Se/C composite.     

Phosphorus(V) porphyrins with axial carbazole-based dendritic substituents

[structure: see text] Three phosphorus(V) porphyrins with axial carbazole-based dendritic substituents (D-A-D) have been designed and synthesized, which are nonfluorescent due to their effective electron transfer from the carbazole dendron to the excited porphyrin within the dendritic matrix. The incident photon to current conversion efficiencies (IPCE) spectra demonstrate that the molecular structure of the dendrimers can significantly affect the photovoltaic response to the visible light.     

Enantiomeric resolution of new triazole compounds by high-performance liquid chromatography

Cellulose tris(3,5-dimethylphenylcarbamate) (CDMPC) was synthesized and coated on aminopropylsilica to prepare a chiral stationary phase (CSP). HPLC methods were developed for the direct enantioseparation of 12 chiral triazole compounds on the CSP. The separations were made using normal phase methodology with a mobile phase consisting of n-hexane-alcohol (ethanol, 1-propanol, 1-butanol, 2-propanol, and t-butanol) in various portions. The column temperatures were studied for the optimization of the resolutions. The effects of structural features of the solutes on the discrimination between the enantiomers were examined. Baseline separation was easily obtained in many cases.     

Enantiomeric separation of chiral pesticides by high performance liquid chromatography on cellulose tris-3,5-dimethyl carbamate stationary phase under reversed phase conditions

Twenty chiral pesticides were tested, of which seven samples were directly separated by HPLC using cellulose tris-3,5-dimethyl carbamate (CDMPC) chiral stationary phase under RP conditions. The influence of mobile phase composition and column temperatures from 0 degrees C to 40 degrees C on the separations were investigated. The mobile phases were methanol/water or ACN/water at a flow rate of 0.8 mL/min with UV detection at 230 or 210 nm. Epoxiconazole, terallethrin, benalaxyl, and diclofopmethyl were observed to obtain the baseline separation under suitable conditions and other pesticides pyriproxyfen, lactofen, and quizalofop-ethyl were separated partially. The retention factors (k) and selectivity factor (alpha) for the enantiomers of most investigated pesticides decreased upon increasing the temperature except for the selectivity factors (alpha) of pyriproxyfen in methanol/water. The ln alpha - 1/T plots for racemic chiral pesticides were linear at the range of 0-40 except for that of pyriproxyfen enantiomers in methanol/water and the chiral separations were controlled by enthalpy. Better separations were not always at low temperature. The elution orders of the eluting enantiomers were determined by a circular dichroism (CD) detector.     

Budding dynamics of individual domains in multicomponent membranes simulated by N-varied dissipative particle dynamics

We study the budding dynamics of individual domains in flat, multicomponent membranes using dissipative particle dynamics (DPD) simulations with varied bead number N, in which addition and deletion of beads based on their density at the membrane boundary is introduced. The budding process of a tubular bud, accompanied by a dynamical transition reflected in the energy and morphology evolutions, is investigated. The simulations show that budding duration is shortened with increasing line tension and depends on the domain size quadratically. At low line tension, increasing bending modulus accelerates budding at first, but suppresses the process as it increases further. In addition, the controlling role of the surface tension in the budding process is also explored. Finally, we use the N-varied DPD to simulate the experimentally observed multicomponent tubular vesicles, and the three bud growth modes are confirmed.     

Polymer structure and the compensation effect of the diffusion pre-exponential factor and activation energy of a permeating solute

In the present work, the relation between the pre-exponential factor and the apparent activation energy of diffusion, ln D(0) = alpha + betaE(D), so-called compensation effect, is re-examined and critically discussed for diffusion of gases in rubbery and glassy polymers. In principle, the above equation could be derived from the enthalpy-entropy compensation in the framework of the transition state theory. However, one should consider the influence of the jump length term contained in the pre-exponential factor, which may be affected by permeating species and polymer properties. We found that parameter alpha depends on penetrant size and polymer properties, such as local chain mobility and free volume. This can be interpreted by the fact that the jump length is affected by both penetrant and polymer properties. Finally, methods for estimating the jump length are discussed.     

Assay of aromatic amino acid enantiomers in rice-brewed suspensions by chiral ligand-exchange CE

The aim of this work was to assay seasoning D- or L-aromatic amino acids (AAs) in rice-brewed suspensions, Laozao in Chinese, by chiral ligand-exchange CE with UV detection and Zn(II) complex as a chiral selecting system. Resolution and peak retention were found to be parallel to the basicity of the AA chiral ligands, and basic L-Arg was known to work the best at pH 8.20 compared with L-Lys and other AA ligands. Baseline separation of DL-aromatic AAs and partially separation of some FMOC-labeled nonaromatic AAs have been achieved using a running buffer of 5 mM ammonium acetate, 100 mM boric acid, 3 mM ZnSO(4), and 6 mM L-Arg at pH 8.20. The aromatic amino acids in four brands of Laozao were measured in a range of 0.25-20 microg/mL for Typ, 1.00-120 microg/mL for Phe, and 2.50-200 microg/mL for Tyr, with linear regression coefficient all over 0.999. The LOD (S/N=3) was 0.15 microg/mL for Typ, 0.50 microg/mL for Phe, and 1.25 microg/mL for Tyr. The recovery of the method determined by spiking with the supernates of Laozao as background was 94.0-112.9%. The RSDs of migration time and peak area measured from six injections of tyrosine were 0.2 and 2.7%, respectively, for run-to-run, and 1.6 and 3.2%, respectively for day-to-day. Interestingly, there were only L-Trp, D-Tyr, and L-Tyr found in the assayed four brands of Laozao. They may serve as an index to recognize the brand of Laozao.     

Analysis of urinary metabolites for metabolomic study by pressurized CEC

A new approach for the metabolomic study of urinary samples using pressurized CEC (pCEC) with gradient elution is proposed as an alternative chromatographic separation tool with higher degree of resolution, selectivity, sensitivity, and efficiency. The pCEC separation of urinary samples was performed on a RP column packed with C(18), 5 microm particles with an ACN/water mobile phase containing TFA. The effects of the acid modifiers, applied voltage, mobile phase, and detection wavelength were systematically evaluated using eight spiked standards, as well as urine samples. A typical analytical trial of urine samples from Sprague Dawley (S.D.) rats exposed to high-energy diet was carried out following sample pretreatment. Significant differences in urinary metabolic profiles were observed between the high energy diet-induced obesity rats and the healthy control rats at the 6th wk postdose. Multivariate statistical analysis revealed the differential metabolites in response to the diet, which were partially validated with the putative standards. This work suggests that such a pCEC-based separation and analysis method may provide a new and cost-effective platform for metabolomic study uniquely positioned between the conventional chromatographic tools such as HPLC, and hyphenated analytical techniques such as LC-MS.