Cobalt complexes supported by salicylichydrazono derivative ligands and various coordination solvents

We report the synthesis and molecular solid-state structures of five novel Co^II and Co^III mononuclear complexes supported by the 2-salicyloylhydrazono-1,3-dithiolane (L1) and 2-salicyloylhydrazono-1,3-dithiane (L2) ligands. Moreover, one novel diamagnetic μ-oxo dinuclear Co^III complex [Co^III₂(HL)₄(μ-O)₂] supported by the ligand L1 was stabilized and characterized. Crystal structure of the supporting ligand L2 was also determined.     

Novel sulfur-containing rapamycin analogs prepared by precursor-directed biosynthesis

[reaction: see text] Two novel sulfur-containing analogs of the immunosuppressive natural product rapamycin (1) were obtained by feeding cultures of Streptomyces hygroscopicus with l-nipecotic acid (4) and either (S)-1,3-thiazane-4-carboxylic acid (5) or (S)-1,4-thiazane-3-carboxylic acid (6). The structures of the two new compounds, 20-thiarapamycin (2) and 15-deoxo-19-sulfoxylrapamycin (3), were determined by spectroscopic methods.     

Synthesis and Conformational Analysis of 2′-Deoxy-2′-(3-methoxybenzamido)adenosine,a rational-designed inhibitor of trypanosomal glyceraldehyde phosphate dehydrogenase (GAPDH)

A series of 2′-benzamido-2′-deoxyadenosine analogues were synthesized in an effort to find new lead structures for the treatment of sleeping sickness. The 2′-deoxy-2′-(3-methoxybenzamido)adenosine ( 1h ) was proved to be a selective inhibitor of the parasite glyceraldehyde 3-phosphate dehydrogenase which confirms the modeling studies. The solution-state conformation of 2′-(thiophene-2-carboxamido) analogue 1d demonstrates a 2′-endo conformation, an orientation of the thiophene ring under the ribose moiety, and the base part occupying a ‘syn’/‘anti’ equilibrium.     

Die Trennung von Hafnium und Zirkonium durch F?llung der Phosphate aus schwefelsaurer L?sung (Schwefels?uremethode)

Ohne Zusammenfassung     

Bayesian inference in surface physics

Bayesian data analysis provides a consistent method for the extraction of information from physics experiments. The approach provides a unified rationale for data analysis, which both justifies many of the commonly used analysis procedures and reveals some of the implicit underlying assumptions. This paper introduces the general ideas of the Bayesian probability theory with emphasis on the application to the evaluation of experimental data, namely the deconvolution of the apparatus function for improving the energy resolution, the reconstruction of depth profiles from Rutherford backscattering measurements, handling of discordant data sets and mixture modelling for background estimation of Auger data. PACS 82.80.Pv; 02.50Tt; 82.80Yc     

Semileptonic decays of d mesons in three-flavor lattice QCD

We present the first three-flavor lattice QCD calculations for D-->pilnu and D-->Klnu semileptonic decays. Simulations are carried out using ensembles of unquenched gauge fields generated by the MILC Collaboration. With an improved staggered action for light quarks, we are able to simulate at light quark masses down to 1/8 of the strange mass. Consequently, the systematic error from the chiral extrapolation is much smaller than in previous calculations with Wilson-type light quarks. Our results for the form factors at q(2)=0 are f(D-->pi)(+)(0)=0.64(3)(6) and f(D-->K)(+)(0)=0.73(3)(7), where the first error is statistical and the second is systematic, added in quadrature. Combining our results with experimental branching ratios, we obtain the Cabibbo-Kobayashi-Maskawa matrix elements |V(cd)|=0.239(10)(24)(20) and |V(cs)|=0.969(39)(94)(24), where the last errors are from experimental uncertainties.     

Deviation from Matthiessen rule in Mg-Cd and Cd-Mg

The interference term between electron-phonon and electron impurity scattering has been evaluated for $\text{Mg}$Cd and $\text{Cd}$Mg and found to be negative, in agreement with experiment. It is shown that measurements on single crystal should give valuable information.