A Novel Synthesis of 5-Aryltropoxe Derivatives

The reaction of substituted arylboronic acids with 5-bromo-2-methoxytropone catalyzed by palladium(0) complex furnished 5-arylated tropone derivatives in good yield.     

Identification,Isolation, and Characterization of Unknown Degradation Products of Cefprozil Monohydrate by High-Performance Thin-Layer Chromatography

JPC – Journal of Planar Chromatography – Modern TLC - The present research work was aimed to determine the stability of cefprozil monohydrate (CEFZ) as per various stress degradation...     

A class of finite difference schemes for interface problems with an HOC approach

In this paper, we propose a new methodology for numerically solving elliptic and parabolic equations with discontinuous coefficients and singular source terms. This new scheme is obtained by clubbing a recently developed higher‐order compact methodology with special interface treatment for the points just next to the points of discontinuity. The overall order of accuracy of the scheme is at least second. We first formulate the scheme for one‐dimensional (1D) problems, and then extend it directly to two‐dimensional (2D) problems in polar coordinates. In the process, we also perform convergence and related analysis for both the cases. Finally, we show a new direction of implementing the methodology to 2D problems in cartesian coordinates. We then conduct numerous numerical studies on a number of problems, both for 1D and 2D cases, including the flow past circular cylinder governed by the incompressible Navier–Stokes equations. We compare our results with existing numerical and experimental results. In all the cases, our formulation is found to produce better results on coarser grids. For the circular cylinder problem, the scheme used is seen to capture all the flow characteristics including the famous von Kármán vortex street. Copyright © 2016 John Wiley & Sons, Ltd.     

Synthesis and Characterization of Related Compounds of Aripiprazole,an Antipsychotic Drug Substance

Three related compounds of aripiprazole were identified during the synthesis. These related compounds were synthesized and characterized by their respective spectral data.     

Thermal degradation kinetics and reaction models of 1,3,5-triamino-2,4,6-trinitrobenzene-based plastic-bonded explosives containing fluoropolymer matrices

In this article, thermal degradation behavior of 1,3,5-triamino-2,4,6-trinitrobenzene (TATB)-based plastic-bonded explosives (PBXs) bonded with a different fluoropolymer matrices namely indigenous poly(vinylidene fluoride-chlorotrifluoroethylene) (FKM), FK 800, fluoroplastic F-32L and fluororubber SKF 32 was investigated through non-isothermal thermogravimetric analysis (TG) technique under nitrogen atmosphere. It was observed that the mass loss of PBXs containing FKM and FK 800 matrices occurred in three steps. The mass loss of PBXs containing fluoroplastic F-32L and fluororubber SKF 32 occurred in two steps. Kinetics were investigated through non-isothermal TG at different heating rates for the first step of degradation by means of model-free Flynn–Wall–Ozawa (FWO) and Kissinger–Akahira–Sunose (KAS) methods. The activation energies calculated by applying FWO method are in good agreement and very close to those obtained by KAS method. The results revealed that the effect of the polymer matrices on the thermal degradation reaction of TATB was significantly observed especially different outcomes of kinetic parameters. The reaction models for degradation were also studied by Criado method. The reaction models are probably best described by the power law and diffusion models.