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61.
In this study, the effect of Ru and Gd promoters on 15Co/\(\gamma\)-Al2O3 catalyst in the Fischer–Tropsch synthesis is investigated. The catalysts were synthesized by dry impregnation method and characterized by XRD, adsorption/desorption of nitrogen, TPR, TEM, ICP and XPS analyses. Activity and selectivity of the catalysts were examined in a fixed bed reactor at 210–230 °C with a H2/CO ratio of 2 and atmospheric pressure. The results showed that the Ru-promoted catalyst has the highest activity and methane selectivity which reduce the chain growth probability. The Gd-promoted catalyst was shown smaller particle size and higher dispersion of cobalt particles in compared with unpromoted catalyst. The smaller particles have more interaction and thus show the lower catalyst reducibility. The presence of Gd in the catalyst cause higher chain growth probability compared to the unpromoted one. The Ru–Gd-promoted catalysts were shown a synergic effect in the catalyst reducibility. Based on the screening of the catalysts in the atmospheric pressure; the unpromoted, 0.1Ru/15Co/Al2O3, and 0.1Ru1Gd/15Co/Al2O3 catalysts were selected to test at high pressure conditions, which the 0.1Ru1Gd/15Co catalyst showed the highest C5 + selectivity (75%) compared with the 0.1Ru/15Co/Al2O3 and the unpromoted one. 相似文献
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63.
Photocatalytic ring opening of α-epoxyketones by 2,4,6-triphenylpyrylium tetrafluoroborate in acetone resulted in the formation of 1,3-dioxolanes as major products through C–O bond cleavage and the formation of alcoholic by-products through C–C bond cleavage. The type and nature of the substituent affects the rate of ring opening. 相似文献
64.
AliReza Nowroozi Haidar Raissi Farzaneh Farzad 《Journal of Molecular Structure》2005,730(1-3):161-169
All the plausible conformations of β-aminoacrolein (AMAC) have been investigated by the Bekes-Lee-Yang-Parr (B3LYP) nonlocal density functional with extended 6-311++G** basis set for studying the stability order of conformers and the various possibilities of intramolecular hydrogen bonding formation. In general the ketoamine (KA) conformers of AMAC, by mean average, are more stable than the corresponding enolimine (EI) and ketoimine (KI) analogues and this stability is mainly due to the π-electron resonance in these conformers that established by NH2 functional group. The contribution of resonance to the stability of chelated KA conformers is about 75.6 kJ/mol, which is greater than that of the hydrogen bond energy (EHB=35.0 kJ/mol). The relative decreasing order of the various hydrogen bond energies was found to be: O–HNimine(strong)>Namine-HOketo (normal)>Nimine-HOhydroxyl (weak) > Nimine-HOketo (weak). Hydrogen bond energies for all systems were obtained from the method that we called related rotamers method (RRM). The topological properties of the electron density contributions for various type of intramolecular hydrogen bond have been analyzed in term of the Bader theory of atoms in molecules (AIM). The results of these calculations support the previous calculations, which obtained by the related rotamer methods. 相似文献
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66.
Suzuki–Miyaura coupling catalyzed by palladium nanoparticles biosynthesized using Glycyrrhiza glabra as reducing and stabilyzing agent 下载免费PDF全文
Hojat Veisi Mehdi Adib Rahman Karimi‐Nami Zahra Yasaei Mahnaz Tajik Talieh Sadat Mosavat Saba Hemmati 《应用有机金属化学》2018,32(3)
An unprecedented environmentally friendly method has been developed for the synthesis of palladium nanoparticles supported on Glycyrrhiza glabra. The synthesized nanoparticles were utilized in Suzuki–Miyaura reaction between different aryl halides and aryl bronic acid in aqueous media. This heterogeneous catalyst can be reused and recycled repeatedly more than five times with only slight loss of its initial catalytic efficiency. This reaction carrid out under atmospheric pressure with high efficiency, unique and simple work‐up procedure and excellent yields. 相似文献
67.
A simple and efficient synthesis of functionalized β‐chlorohydrins is described from the regio‐ and stereoselective reaction of α‐epoxyketones with AlCl3 in acetonitrile at room temperature. 相似文献
68.
Luo Shaohua Li Shaobo Yang Guanci Ouakad Hassen M. Karami Farzad 《Nonlinear dynamics》2020,101(1):293-309
Nonlinear Dynamics - This paper mainly investigates dynamical analysis and anti-oscillation-based adaptive control issues of the fractional-order (FO) arch microelectromechanical system (MEMS) with... 相似文献
69.
Sepideh Fereshteh Hourieh Kalhor Amin Sepehr Hamzeh Rahimi Mahdi Zafari Reza Ahangari Cohan Farzad Badmasti 《印度化学会志》2022,99(2):100319
BackgroundAcinetobacter baumannii is a highly antimicrobial resistant nosocomial pathogen. Resistance to currently used antibiotics has limited effective drugs against this bacterium. This study aimed to propose a rational inhibitor design against the LpxA protein of A. baumannii using a virtual screening method based on a similar structure of ligands.MethodsIn this study, we targeted LpxA protein, which is involved in the early stage of LPS biosynthesis. In the next step, we used Peptide920 and 1,2- Ethanediol as templates to find similar compounds using Drugbank and Zinc15 webservers, respectively. Subsequently, molecular dynamics (MD) simulations were carried out for LpxA protein and two complexes of ZINC895081 and Macrolactam-1 which represented the highest binding affinity and best conformation. Finally, ADMET properties, water solubility and drug-likeness of the desired compounds were evaluated using SwissADME and DruLiTo softwares.ResultsAccording to considered criteria, Drugbank suggested 5 compunds including Ilomastat, Macrolactam-1, Macrolactam-2, Macimorelin, and Oglufanide. On the other hand, Zinc15 webserver suggested 4 compunds including ZINC895048, ZINC895081, ZINC901061 and ZINC1531008. The result of the HDOCK server and Molegro virtual docker (MVD) showed that Macrolactam-1 and ZINC895081 (Citrate) had the highest docking score. In addition, MD simulations showed that ZINC895081 and Macrolactam-1 ligands have the stable binding to the LpxA protein. According to Lipinski's rule, these two compounds are non-carcinogenic, non-toxic and promising inhibitors against LpxA of A. baumannii.ConclusionIt seems that Macrolactam-1 and ZINC895081 (Citrate) are two valuable promising inhibitors against the LpxA protein of A. baumannii. Further in vitro and in vivo experiments are needed to confirm the capabilities of these proposed compounds against A. baumannii. 相似文献
70.
Cytidine triphosphate synthetase (CTPS) catalyzes the formation of cytidine triphosphate from glutamine, uridine-5'-triphosphate (UTP), and adenosine-5'-triphosphate. Inhibitors of CTPS are of interest because of their potential as therapeutic agents. One approach to potent enzyme inhibitors is to use analogues of high energy intermediates formed during the reaction. The CTPS reaction proceeds via the high energy intermediate UTP-4-phosphate (UTP-4-P). Four novel analogues of uridine-4-phosphate (U-4-P) and 3-deazauridine-4-phosphate (3-deazaU-4-P) were synthesized in which the labile phosphate ester oxygen was replaced with a methylene and difluoromethylene group. The methylene analogue of U-4-P, compound 1, was prepared by a reaction of the sodium salt of tert-butyl diethylphosphonoacetate with protected, 4-O-activated uridine followed by acetate deprotection and decarboxylation. It was found that this compound undergoes relatively facile dephosphonylation presumably via a metaphosphate intermediate. The difluoromethylene derivative, compound 2, was prepared by electrophilic fluorination of protected 1. This compound was stable and did not undergo dephosphonylation. Synthesis of the methylene analogue of 3-deazaU-4-P, compound 3, was achieved by ribosylation of protected 4-(phosphonomethyl)-2-hydroxypyridine. Electrophilic fluorination was also employed in the preparation of protected 4-(phosphonodifluoromethyl)-2-hydroxypyridine which was used as the key building block in the synthesis of difluoro derivative 4. These compounds represent the first examples of a nucleoside in which the base has been chemically modified with a methylene or difluormethylenephosphonate group. 相似文献