全文获取类型
收费全文 | 993篇 |
免费 | 18篇 |
国内免费 | 7篇 |
专业分类
化学 | 544篇 |
晶体学 | 5篇 |
力学 | 33篇 |
数学 | 88篇 |
物理学 | 348篇 |
出版年
2021年 | 6篇 |
2020年 | 7篇 |
2019年 | 8篇 |
2018年 | 10篇 |
2017年 | 9篇 |
2016年 | 15篇 |
2015年 | 8篇 |
2014年 | 10篇 |
2013年 | 42篇 |
2012年 | 29篇 |
2011年 | 47篇 |
2010年 | 33篇 |
2009年 | 18篇 |
2008年 | 24篇 |
2007年 | 42篇 |
2006年 | 27篇 |
2005年 | 37篇 |
2004年 | 28篇 |
2003年 | 40篇 |
2002年 | 27篇 |
2001年 | 22篇 |
2000年 | 32篇 |
1999年 | 14篇 |
1997年 | 16篇 |
1996年 | 39篇 |
1995年 | 34篇 |
1994年 | 19篇 |
1993年 | 34篇 |
1992年 | 31篇 |
1991年 | 14篇 |
1990年 | 8篇 |
1989年 | 11篇 |
1988年 | 7篇 |
1987年 | 12篇 |
1986年 | 13篇 |
1985年 | 13篇 |
1984年 | 11篇 |
1983年 | 9篇 |
1982年 | 21篇 |
1981年 | 17篇 |
1979年 | 10篇 |
1978年 | 10篇 |
1977年 | 8篇 |
1976年 | 6篇 |
1975年 | 13篇 |
1974年 | 9篇 |
1973年 | 7篇 |
1972年 | 10篇 |
1969年 | 6篇 |
1966年 | 7篇 |
排序方式: 共有1018条查询结果,搜索用时 15 毫秒
61.
Jennifer T. Duong Mark J. Bailey Teresa E. Pick Patrick M. McBride Evelyn L. Rosen Raffaella Buonsanti Delia J. Milliron Brett A. Helms 《Journal of polymer science. Part A, Polymer chemistry》2012,50(18):3719-3727
Water‐dispersible, polymer‐wrapped nanocrystals are highly sought after for use in biology and chemistry, from nanomedicine to catalysis. The hydrophobicity of their native ligand shell, however, is a significant barrier to their aqueous transfer as single particles. Ligand exchange with hydrophilic small molecules or, alternatively, wrapping over native ligands with amphiphilic polymers is widely employed for aqueous transfer; however, purification can be quite cumbersome. We report here a general two‐step method whereby reactive stripping of native ligands is first carried out using trialkyloxonium salts to reveal a bare nanocrystal surface. This is followed by chemically directed immobilization of a hydrophilic polymer coating. Polyacrylic acids, with side‐chain grafts or functional end groups, were found to be extremely versatile in this regard. The resulting polymer‐wrapped nanocrystal dispersions retained much of the compact size of their bare nanocrystal precursors, highlighting the unique role of monomer side‐chain functionality to serve as effective, conformal ligation motifs. As such, they are well poised for applications where tailored chemical functionality at the nanocrystal's periphery or improved access to their surfaces is desirable. © 2012 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2012 相似文献
62.
A. Anghel T. L. Bailey G. Bison B. Blau L. J. Broussard S. M. Clayton C. Cude-Woods M. Daum A. Hawari N. Hild P. Huffman T. M. Ito K. Kirch E. Korobkina B. Lauss K. Leung E. M. Lutz M. Makela G. Medlin C. L. Morris R. W. Pattie D. Ries A. Saunders P. Schmidt-Wellenburg V. Talanov A. R. Young B. Wehring C. White M. Wohlmuther G. Zsigmond 《The European Physical Journal A - Hadrons and Nuclei》2018,54(9):148
63.
Harry Adams Neil A. Bailey David E. Fenton Choki Fukuhara Masatoshi Kanesato 《Supramolecular chemistry》2013,25(4):325-330
Abstract The synthesis and crystal structure of the diprotonated cryptand derived from the reaction of tren and 2,6-diacetyl pyridine is reported. The imino nitrogens of the Schiff base linkages are directed so that the dicarbimine functions are in trans, trans geometry relative to the pyridine C-N bond. This configuration has not previously been reported in related pyridine-derived Schiff base macrocycles. 相似文献
64.
A simple one-step synthesis of alkyl benzazol-2-carboxylates employing alkyl trialkoxyacetate is described. 相似文献
65.
Nicola A. Bailey Darran R. Cairns Gregory P. Crawford James N. Hay 《Liquid crystals》2013,40(12):1761-1765
A liquid crystal, BL038, which was observed not to crystallize, has a glass transition at 215 K and a nematic to isotropic transition at 380 K. Samples aged below the glass transition at various temperatures T a, exhibited an endotherm at the transition which developed with extent of ageing time, t a. We attribute this endotherm to the relaxation of the glass towards the equilibrium liquid. The progress of the relaxation process was measured using differential scanning calorimetry. On subsequent reheating, the aged glass showed an apparent shift in the glass transition to higher temperatures. The endotherm was used to define the extent of enthalpic relaxation and the maximum value observed was found to increase initially then decrease, with the extent of undercooling from the glass transition temperature, Δ T, passing through a maximum for a Δ T = 15 K. From the temperature dependence of the relaxation times, an apparent activation enthalpy for the relaxation process of 85 ± 10 kJ mol-1 was determined. The small value of the activation enthalpy compared with that found in the ageing of polymers reflects differences in the molecular species involved in relaxation processes. 相似文献
66.
B. W. Bailey J. M. Rankin R. Weinbloom 《International journal of environmental analytical chemistry》2013,93(1):3-9
The use of ternary complexes in the determination of anionic surfactants has been investigated and an analytical method using linear alkyl sulfonates as a test substance has been developed. The method involves the formation of the chloroform-extractable bisphenanthroline Cu(II)-linear alkyl sulfonate (LAS) complex and the subsequent equilibration of the extract with erythrosine to form the extractable bisphenanthroline Cu(II)-erythrosine complex. In the equilibration step erythrosine displaces LAS quantitatively, allowing the determination of the LAS originally present by measuring the absorbance of the extracted bisphenanthroline-Cu(II)-erythrosine complex. Results are reported of studies made to determine the optimum analytical conditions, the sensitivity, and the precision for the method described. 相似文献
67.
68.
69.
70.
Joshua Buse Randy W. Purves Ronald E. Verrall Ildiko Badea Haixia Zhang Christopher C. Mulligan Kerry M. Peru Jonathan Bailey John V. Headley Anas El‐Aneed 《Journal of mass spectrometry : JMS》2014,49(11):1171-1180
The safe use of lipid‐based drug delivery agents requires fast and sensitive qualitative and quantitative assessment of their cellular interactions. Many mass spectrometry (MS) based analytical platforms can achieve such task with varying capabilities. Therefore, four novel high‐throughput MS‐based quantitative methods were evaluated for the analysis of a small organic gene delivery agent: N,N‐bis(dimethylhexadecyl)‐1,3‐propane‐diammonium dibromide (G16‐3). Analysis utilized MS instruments that detect analytes using low‐resolution tandem MS (MS/MS) analysis (i.e. QTRAP or linear ion trap in this work) or high‐resolution MS analysis (i.e. time of flight (ToF) or Orbitrap). Our results indicate that the validated fast chromatography (FC)‐QTRAP‐MS/MS, FC‐ LTQ‐Orbitrap‐MS, desorption electrospray ionization‐collision‐induced dissociation (CID)‐MS/MS and matrix assisted laser desorption ionization‐ToF/ToF‐MS MS methods were superior in the area of method development and sample analysis time to a previously developed liquid chromatography (LC)‐CID‐MS/MS. To our knowledge, this is the first evaluation of the abilities of five MS‐based quantitative methods that target a single pharmaceutical analyte. Our findings indicate that, in comparison to conventional LC‐CID‐MS/MS, the new MS‐based methods resulted in a (1) substantial reduction in the analysis time, (2) reduction in the time required for method development and (3) production of either superior or comparable quantitative data. The four new high‐throughput MS methods, therefore, were faster, more efficient and less expensive than a conventional LC‐CID‐MS/MS for the quantification of the G16‐3 analyte within tissue culture. When applied to cellular lysate, no significant change in the concentration of G16‐3 gemini surfactant within PAM212 cells was observed between 5 and 53 h, suggesting the absence of any metabolism/excretion from PAM212 cells. Copyright © 2014 John Wiley & Sons, Ltd. 相似文献